Results 71 to 80 of about 1,147,179 (336)

The differential protein and lipid compositions of noncaveolar lipid microdomains and caveolae [PDF]

Cell Research, 2009
Morphologically, caveolae and lipid rafts are two different membrane structures. They are often reported to share similar lipid and protein compositions, and are considered to be two subtypes of membrane lipid microdomains. By modifying sucrose density gradient flotation centrifugation, which is used to isolate lipid microdomains, we were able to ...
Yao, Yao, Shangyu, Hong, Hu, Zhou, Taichang, Yuan, Rong, Zeng, Kan, Liao   +5 more
openaire   +2 more sources

Multivalent ligands of CD22 for targeting of B cells [PDF]

, 2009
Multivalent ligands of CD22 for active targeting of B cells. Mary O’Reilly, Wei Hsu Chen, Gladys Completo, Ying Zeng, Satoshi Futakawa and Cory Rillahan and James C.
James C. Paulson
core   +1 more source

Membrane fluidity matters: Hyperthermia from the aspects of lipids and membranes [PDF]

, 2013
Hyperthermia is a promising treatment modality for cancer in combination both with radio- and chemotherapy. In spite of its great therapeutic potential, the underlying molecular mechanisms still remain to be clarified.
Ahyayauch H, Anderson RL, Angelucci C, Balboa MA, Balint Csoboz, Balogh G, Balogh G, Balogi Z, Balogi Z, Balsinde J, Batko J, Benkö S, Brameshuber M, Burcin Gungor, Cadenas C, Calderwood SK, Calderwood SK, Carracedo A, Chau LY, Chung J, Corda D, Crul T, Erzsebet Kusz, Escribá P V, Funaki N, Gabai VL, Gabor E. Balogh, Giocondi M-C, Gombos I, Gordana Bogdanovics, Grassme H, Griner EM, Heilbrunn LV, Hirabayashi T, Horváth I, Horváth I, Horváth I, Horváth I, Hønger T, Hønger T, Ibolya Horvath, Imre Gombos, Juhász K, Jurivich DA, Kiang JG, Kirkegaard T, Klose C, Koklic T, Lajos Haracska, Laszlo Vigh, Mace TA, Maria Peter, Menendez JA, Miller RC, Mukherjee S, Nagy E, Nakamoto H, Nomura DK, Noonan EJ, Olivera-Couto A, Ostberg JR, Pallepati P, Patra SK, Peer AJ, Péter M, Redman CA, Samples BL, Segui B, Sherbet G V, Shigapova N, Shimizu T, Simons K, Sok M, Takahashi A, Tang X, Taraboletti G, Tim Crul, Tsvetkova NM, Török Z, Török Z, Török Z, Vigh L, Vigh L, Vigh L, Vigh L, Vigh L, Vigh L, Vigh L, Wakelam MJ, Wymann MP, Yatvin MB, Yukihara M, Zeisig R, Zhang F, Zsolt Torok   +94 more
core   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Comparative lipidomics in clinical isolates of Candida albicans reveal crosstalk between mitochondria, cell wall integrity and azole resistance. [PDF]

PLoS ONE, 2012
Prolonged usage of antifungal azoles which target enzymes involved in lipid biosynthesis invariably leads to the development of multi-drug resistance (MDR) in Candida albicans.
Ashutosh Singh, Vipin Yadav, Rajendra Prasad   +2 more
doaj   +1 more source

α1-nAchR-Mediated Signaling Through Lipid Raft Is Required for Nicotine-Induced NLRP3 Inflammasome Activation and Nicotine-Accelerated Atherosclerosis

Frontiers in Cell and Developmental Biology, 2021
BackgroundNicotine exerts direct effects on multiple cell types in the cardiovascular system by associating with its high-affinity nicotinic acetylcholine receptors (nAchRs).
Fengqi Duan, Cheng Zeng, Sijun Liu, Jianfeng Gong, Jia Hu, Hongyu Li, Hongmei Tan, Hongmei Tan, Hongmei Tan   +8 more
doaj   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Glycosphingolipid GM3 is localized in both exoplasmic and cytoplasmic leaflets of Plasmodium falciparum malaria parasite plasma membrane

Scientific Reports, 2021
Lipid rafts, sterol-rich and sphingolipid-rich microdomains on the plasma membrane are important in processes like cell signaling, adhesion, and protein and lipid transport.
Shiomi Koudatsu, Tatsunori Masatani, Rikako Konishi, Masahito Asada, Hassan Hakimi, Yuna Kurokawa, Kanna Tomioku, Osamu Kaneko, Akikazu Fujita   +8 more
doaj   +1 more source

Membrane-Sculpting BAR Domains Generate Stable Lipid Microdomains

Cell Reports, 2013
Bin-Amphiphysin-Rvs (BAR) domain proteins are central regulators of many cellular processes involving membrane dynamics. BAR domains sculpt phosphoinositide-rich membranes to generate membrane protrusions or invaginations. Here, we report that, in addition to regulating membrane geometry, BAR domains can generate extremely stable lipid microdomains by "
Zhao, Hongxia, Michelot, Alphée, Koskela, Essi V, Tkach, Vadym, Stamou, Dimitrios, Drubin, David G, Lappalainen, Pekka   +6 more
openaire   +6 more sources