Results 171 to 180 of about 88,630 (306)

Understanding Size Distributions during Lipid Nanoparticle Manufacturing through Mechanistic Modeling. [PDF]

ACS Omega
Mukherjee S, Shin S, Devos C, Udepurkar A, Sagmeister P, Trout BL, Myerson AS, Braatz RD.   +7 more
europepmc   +1 more source

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

Advanced Science, EarlyView.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou, Qiming Zhai, Zhihao Yao, Qing Li, Yan Yang, Si Wang, Chao Huang, Liangjing Xin, Tao Chen, Jinlin Song   +9 more
wiley   +1 more source

Effect of Short-Anchored PEGylated Lipids on Lipid Nanoparticle Characterization Profiles, Stability, and Efficacy. [PDF]

Biomedicines
Souleyrette CER, West PC, Kirkpatrick SS, Arnold JD, Buckley MR, Freeman MB, Grandas OH, Grimsley LB, McNally MM, Mountain DJH.   +9 more
europepmc   +1 more source

Lipid nanoparticle of tobramycin

, 2015
A1 Solicitud de patente con informe sobre el estado de la ...
Gainza Lafuente, Eusebio, Villullas Rincón, Silvia, Ibarrola Moreno, Oihane, Gainza Lucea, Garazi, Herrán Martínez, Enara, Aguirre Anda, José Javier, Pozo, Ángel del, Pedraz Muñoz, José Luis, Esquisabel Alegría, Amaia, Moreno-Sastre, María, Pastor Navarro, Marta, Viñas Ciordia, Miguel, Vinuesa Aumedes, María Teresa, Bachiller, Daniel   +13 more
openaire   +1 more source

Oral Motion‐Powered Smart Dental Implant Abutment for In Situ Antibacterial and Cell Adhesion Through Piezoelectric Effect

Advanced Science, EarlyView.
We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi, Xiaoyu Han, Yanhui Lu, Yuan Chai, Baiyan Xiao, Shuo Liu, Boon Chin Heng, Tingting Wu, Tingjun Li, Qiaomei Ren, Ting Song, Le Chen, Dong Han, Yaru Guo, Xuliang Deng, Xuehui Zhang   +15 more
wiley   +1 more source

Recent Developments in Lipid Nanoparticle-Mediated Delivery of Biotherapeutics and Gene Therapy Across the Blood-Brain Barrier. [PDF]

BioDrugs
Iqbal U, Hwang RW, Costain WJ.
europepmc   +1 more source

Hepatoma‐Derived Growth Factor Coordinates STAT3 Pathway and Exosome‐Mediated Intrahepatic Crosstalk to Control Hepatic Steatosis and MASLD

Advanced Science, EarlyView.
Hepatic HDGF as a key mediator in coordinating hepatic steatosis and intrahepatic crosstalk in MASLD. Activation of HDGF facilitates its interaction with both STAT3 and S6K1, driving the S6K1‐dependent STAT3 phosphorylation and subsequently enhancing hepatic lipogenesis.
Jian Wen, Dong Ding, Zengpeng Zheng, Xufeng Chen, Wenjing Li, Jiaxin Shen, Zhiwei Huang, Peng Tan, Junjie Bai, Xia Fang, Baofang Xing, Puyuan Hu, Linghao Xu, Haokai Yu, Yixi Wang, Zongzhe Jiang, Yang Long, Tiejun Zhou, Mingxin Ye, Yu Jiang, Aoyuan Cui, Hong Li, Qiurong Ding, Yong Xu, Yu Li, Weitong Su, Feng Shen, Chenlin Gao, Wenguang Fu   +28 more
wiley   +1 more source

Molecular dynamics simulations of heat transfer in gold nanoparticle-lipid bilayer systems

, 2017
Nanoparticle-membrane interactions play a key role in many important applications such as drug delivery, nanomedicine, biosensors, electronic devices, imaging, diagnostics and cosmetics. Evidently, theoretical and experimental studies of nanoparticle and
Potdar, Dipti
core  

A novel auto-fluorescent porphyrin-lipid nanoparticle strategy for CTNNB1 gene silencing in hepatocellular carcinoma. [PDF]

Front Oncol
To JC, Apilan A, Pasini E, Mo Y, Chen J, Bakrania A, Bu J, Pan A, Adeyi O, Vogel A, Zheng G, Bhat M.   +11 more
europepmc   +1 more source

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source