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Lipid peroxidation in erythrocytes
Chemistry and Physics of Lipids, 1987Erythrocytes might be expected to be highly susceptible to peroxidation. Their membranes are rich in polyunsaturated fatty acids; they are continuously exposed to high concentrations of oxygen; and they contain a powerful transition metal catalyst. In fact, autoxidation is held in check in vivo by extremely efficient protective antioxidant mechanisms ...
M R, Clemens, H D, Waller
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Measurement of Lipid Peroxidation
Free Radical Research, 1998Lipid peroxidation results in the formation of conjugated dienes, lipid hydroperoxides and degradation products such as alkanes, aldehydes and isoprostanes. The approach to the quantitative assessment of lipid peroxidation depends on whether the samples involve complex biological material obtained in vivo, or whether the samples involve relatively ...
K, Moore, L J, Roberts
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Critical Reviews in Oncology/Hematology, 1993
Lipid peroxidation, firstly described as a mechanism of lipid deterioration by chemists, is now considered as a major mechanism of elementary lesion in living cells, and in many cases the major cause for their death. In living animals, it was firstly described to increase after irradiation [23,32,252] and then in vitamin E deficiency [57,258,259].
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Lipid peroxidation, firstly described as a mechanism of lipid deterioration by chemists, is now considered as a major mechanism of elementary lesion in living cells, and in many cases the major cause for their death. In living animals, it was firstly described to increase after irradiation [23,32,252] and then in vitamin E deficiency [57,258,259].
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Lipid peroxidation in homocysteinaemia
Journal of Inherited Metabolic Disease, 1992Homocysteinaemia due to cystathione synthase deficiency (CSD: McKusick 236200) is a rare autosomal recessive inborn error of methionine metabolism. The most life-threatening complications caused by CSD are thromboembolism and vascular abnormalities.
H J, Blom +7 more
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Thiol-dependent lipid peroxidation
Biochemical and Biophysical Research Communications, 1982Abstract Initiation of lipid peroxidation in liposomes by cysteine, glutathione, or dithiothreitol required iron, and was not inhibited by superoxide dismutase. The absence of superoxide involvement in thiol autoxidation was confirmed by the inability of superoxide dismutase to inhibit thiol reduction of cytochrome c.
M, Tien, J R, Bucher, S D, Aust
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Lipid peroxidation in spermatozoa
Proceedings of the Royal Society of London. Series B. Biological Sciences, 1973Ram spermatozoa produce aerobically an organic peroxide which can be determined quantitatively by the thiobarbituric acid reaction. The reaction is more intense in spermatozoa that have been stored at 5°C. Cold shock and homogenization release from spermatozoa a substance, presumably a lipid, which provides the substrate for peroxidation.
R, Jones, T, Mann
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Mechanisms of lipid peroxidation
Journal of Free Radicals in Biology & Medicine, 1985This article provides an overview of how peroxidation of unsaturated lipids takes place and how it can be measured. Several different aspects of free-radical-mediated lipid peroxidation are discussed, including: the catalytic role of chelated iron and other redox metal ions; induction by reducing agents such as superoxide, ascorbate, and xenobiotic ...
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Transferrin-dependent lipid peroxidation
Advances in Free Radical Biology & Medicine, 1986The potential for iron bound to transferrin to be released and promote the peroxidation of phospholipid liposomes was investigated using ADP as a low molecular weight chelator and superoxide generated by the xanthine/xanthine oxidase system as the reducing agent.
M, Saito, L A, Morehouse, S D, Aust
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Paraquat and Lipid Peroxidation
Archives of Internal Medicine, 1982To the Editor. —In the AugustArchives(1981;141:1169-1171), Yasaka et al reported an increase in lipid peroxidation (as measured by serum malondialdehyde levels) after ingestion of paraquat, a bipyridinium compound widely used as a herbicide. The authors suggested that the serum malondialdehyde may have originated from passage of the blood through the ...
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Inhibition of lipid peroxidation
Biological Trace Element Research, 1997Lipid peroxy radicals (ROO.) were detected by electron spin resonance (ESR) at low temperature after formation by addition of H2O2 into a suspension of mice lymphocytes. If lymphocytes were treated with selenomethionine (Se-Met) prior to addition of H2O2, ROO. formation was inhibited in a fashion that was dependent on Se-Met concentration. Formation of
E, Sun +5 more
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