Medicinal research reviews (Print), 2020 The world's population aging progression renders age‐related neurodegenerative diseases to be one of the biggest unsolved problems of modern society.
Plamena R. Angelova +2 more
semanticscholar +1 more source
The Journal of Clinical Investigation, 2022 CD8+ T cell longevity regulated by metabolic activity plays important roles in cancer immunotherapy. Although in vitro–polarized, transferred IL-9–secreting CD8+ Tc9 (cytotoxic T lymphocyte subset 9) cells exert greater persistence and antitumor efficacy
Liuling Xiao +10 more
doaj +1 more source
New Marker of Colon Cancer Risk Associated with Heme Intake: 1,4-Dihydroxynonane Mercapturic Acid [PDF]
, 2006 Background: Red meat consumption is associated with an increased risk of colon cancer. Animal studies show that heme, found in red meat, promotes preneoplastic lesions in the colon, probably due to the oxidative properties of this compound.
Bingham, Sheila A. +8 more
core +3 more sources
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation
Cell Death and Differentiation, 2020 Protein aggregation and abnormal lipid homeostasis are both implicated in neurodegeneration through unknown mechanisms. Here we demonstrate that aggregate-membrane interaction is critical to induce a form of cell death called ferroptosis.
Plamena R. Angelova +18 more
semanticscholar +1 more source
A simple method to assess the oxidative susceptibility of low density lipoproteins [PDF]
, 2001 BACKGROUND: Oxidative modification of low density lipoproteins (LDL) is recognized as one of the major processes involved in atherogenesis. The in vitro standardized measurement of LDL oxidative susceptibility could thus be of clinical significance.
A Lavy +19 more
core +4 more sources
Lipid Peroxidation in Oral Cancer [PDF]
Basrah Journal of Surgery, 2003 In this study, 20 patients with oral cancer (confirmed by histopathological examination) and 21 control subjects were included, to evaluate the degree of lipid peroxidation (LP) in oral cancer.
Ghaydaa H. Badri
doaj +1 more source
Delayed treatment with nimesulide reduces measures of oxidative stress following global ischemic brain injury in gerbils [PDF]
, 2003 Metabolism of arachidonic acid by cyclooxygenase is one of the primary sources of reactive oxygen species in the ischemic brain. Neuronal overexpression of cyclooxygenase-2 has recently been shown to contribute to neurodegeneration following ischemic ...
Alvarez, Dalia +3 more
core +1 more source
Lipid peroxidation is a nonparenchymal cell event with reperfusion after prolonged liver ischemia [PDF]
, 1990 A proposed mechanism for irreversible ischemic liver damage has been peroxidation of membrane phospholipids by free radicals. However, the hepatocyte is laden with enzymes which are antioxidants and, therefore, ought to be relatively resistant to ...
Makowka, L +3 more
core +1 more source
The role of nitric oxide and lipid peroxidation in patients with Plasmodium vivax malaria
Parasite, 2002 In this study, we investigated the role of nitric oxide metabolism and lipid peroxidation in patients with P. vivax malaria. The levels of nitrite and nitrate were analyzed using a procedure based on the Griess reaction and malondialdehyde levels which ...
Polat G. +5 more
doaj +1 more source
Phlorotannin Extracts from Fucales Characterized by HPLC-DAD-ESI-MSn: Approaches to Hyaluronidase Inhibitory Capacity and Antioxidant Properties [PDF]
, 2019 Purified phlorotannin extracts from four brown seaweeds (Cystoseira nodicaulis (Withering) M. Roberts, Cystoseira tamariscifolia (Hudson) Papenfuss, Cystoseira usneoides (Linnaeus) M.
Andrade, Paula +6 more
core +1 more source