New Marker of Colon Cancer Risk Associated with Heme Intake: 1,4-Dihydroxynonane Mercapturic Acid [PDF]
Background: Red meat consumption is associated with an increased risk of colon cancer. Animal studies show that heme, found in red meat, promotes preneoplastic lesions in the colon, probably due to the oxidative properties of this compound.
G. Gottardi +21 more
core +1 more source
Effect of ultraviolet-B radiation on biomass production, lipid peroxidation, reactive oxygen species, and antioxidants in Withania somnifera [PDF]
The present study was aimed at understanding the effects of long term supplemental UV-B (3.6 kJ m-2 d-1) on biomass production, accumulation of reactive oxygen species, lipid peroxidation, and enzymatic antioxidants in leaves and roots of Withania ...
S. Takshak, S. B. Agrawal
core +1 more source
The role of nitric oxide and lipid peroxidation in patients with Plasmodium vivax malaria
In this study, we investigated the role of nitric oxide metabolism and lipid peroxidation in patients with P. vivax malaria. The levels of nitrite and nitrate were analyzed using a procedure based on the Griess reaction and malondialdehyde levels which ...
Polat G. +5 more
doaj +1 more source
Site-specific peroxidation modulates lipid bilayer mechanics [PDF]
Peroxidation of plasma membranes, characterized by oxidative attack of lipidic carbon–carbon double bonds in unsaturated fatty acids, has been identified as an important biochemical event in multiple pathological conditions, including neurodegenerative ...
Chng, Choon-Peng +3 more
core +1 more source
Nitric oxide and lipid peroxidation [PDF]
Nitric oxide can both promote and inhibit lipid peroxidation. By itself, nitric oxide acts as a potent inhibitor of the lipid peroxidation chain reaction by scavenging propagatory lipid peroxyl radicals.
Kalyanaraman, B, Hogg, Neil
core +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Lipid peroxidation is essential for α-synuclein-induced cell death. [PDF]
Parkinson's disease is the second most common neurodegenerative disease and its pathogenesis is closely associated with oxidative stress. Deposition of aggregated α-synuclein (α-Syn) occurs in familial and sporadic forms of Parkinson's disease.
Klenerman, D +5 more
core
Assay of the antioxidant capacity of foods using an iron(II)-catalysed lipid peroxidation model for greater nutritional relevance [PDF]
The formation of free radicals by the iron-catalysed Fenton reaction is a major cause of oxidative damage in the body. Here a common assay of antioxidant capacity, inhibition of the β-carotene-linoleic acid model of lipid peroxidation, has been modified ...
Molan, Peter C. +3 more
core +1 more source
Mechanisms and active substances of targeting lipid peroxidation in ferroptosis regulation
Ferroptosis is a novel form of cell death driven by iron-dependent lipid peroxidation and it is implicated in various diseases, such as liver disease, acute kidney injury, cardiovascular disease, neurodegenerative disease and cancer. Lipid-based reactive
Hui Chen, Lingli Chen, Wenjun Wang
doaj +1 more source
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source

