Results 51 to 60 of about 1,407,330 (363)
FEBS Open Bio, EarlyView.SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel +13 more
wiley +1 more source
A Lipid-Structured Model of Atherosclerotic Plaque Macrophages with Lipid-Dependent Kinetics [PDF]
arXiv, 2022 Atherosclerotic plaques are fatty growths in artery walls that cause heart attacks and strokes. Plaque formation is orchestrated by macrophages that are recruited to the artery wall to consume and remove blood-derived lipids, such as low-density lipoprotein (LDL).
arxiv
Lipid peroxidation in eclampsia
Journal of Obstetrics and Gynaecology, 1997 In order to investigate the extent of lipid peroxidation in hypertensive disorders of pregnancy, a case-control study was designed. Eight eclamptic women were matched with women with severe pre-eclampsia (n = 8) and healthy pregnant controls (n = 8).
G J Hofmeyr +2 more
openaire +3 more sources
FEBS Open Bio, EarlyView.The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli +15 more
wiley +1 more source
Selective electrochemical generation of hydrogen peroxide from water oxidation [PDF]
J. Phys. Chem. Lett., 2015, 6, 4224-4228, 2015 Water is a life-giving source, fundamental to human existence, yet, over a billion people lack access to clean drinking water. Present techniques for water treatment such as piped, treated water rely on time and resource intensive centralized solutions.
arxiv +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objectives An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation in Parkinson's disease and to evaluate the biomarker potential of methylation‐based ...
Ingeborg Haugesag Lie +4 more
wiley +1 more source
Regulation of lipid peroxidation and ferroptosis in diverse species
Genes & Development, 2018 This review by Conrad et al. reviews the functions and regulation of lipid peroxidation, ferroptosis, and the antioxidant network in diverse species, including humans, other mammals and vertebrates, plants, invertebrates, yeast, bacteria, and archaea ...
M. Conrad +6 more
semanticscholar +1 more source
Light‐Triggered Protease‐Mediated Release of Actin‐Bound Cargo from Synthetic Cells
Advanced Biology, EarlyView.TEV Prtoease‐mediated Releasable Actin‐binding Protein (TRAP) is a protein‐based platform consisting of a cargo tightly bound to reconstituted actin networks in synthetic cells which can be proteolyticly released from the bound actin, followed by its secretion through membrane translocation mediated by a cell‐penetrating peptide.
Mousumi Akter +3 more
wiley +1 more source
Increased unsaturated lipids underlie lipid peroxidation in synucleinopathy brain
Acta Neuropathologica Communications, 2022 Lipid peroxidation is a process of oxidative degradation of cellular lipids that is increasingly recognized as an important factor in the pathogenesis of neurodegenerative diseases.
YuHong Fu +8 more
doaj +1 more source
Iron toxicity, lipid peroxidation and ferroptosis after intracerebral haemorrhage
Stroke and vascular neurology, 2019 Intracerebral haemorrhage (ICH) is a devastating type of stroke with high mortality and morbidity. However, we have few options for ICH therapy and limited knowledge about post-ICH neuronal death and related mechanisms.
Jie-ru Wan, Honglei Ren, Jian Wang
semanticscholar +1 more source