Results 101 to 110 of about 69,365 (334)

Proving lipid rafts exist: membrane domains in the prokaryote Borrelia burgdorferi have the same properties as eukaryotic lipid rafts.

open access: yesPLoS Pathogens, 2013
Lipid rafts in eukaryotic cells are sphingolipid and cholesterol-rich, ordered membrane regions that have been postulated to play roles in many membrane functions, including infection.
Timothy J LaRocca   +6 more
doaj   +1 more source

Membrane lipid raft organization during cotton fiber development

open access: yesJournal of Cotton Research, 2020
Background Cotton fiber is a single-celled seed trichome that originates from the ovule epidermis. It is an excellent model for studying cell elongation.
Fan XU   +6 more
doaj   +1 more source

Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells [PDF]

open access: yes, 2018
Canine respiratory coronavirus (CRCoV), identified in 2003, is a member of the Coronaviridae family. The virus is a betacoronavirus and a close relative of human coronavirus OC43 and bovine coronavirus.
A Milewska   +75 more
core   +8 more sources

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

open access: yesAdvanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto   +11 more
wiley   +1 more source

Microcavity supported lipid membranes: versatile platforms for building asymmetric lipid bilayers and for protein recognition [PDF]

open access: yes, 2019
Microcavity supported lipid bilayers (MSLB) are contact-free membranes suspended across aqueousfilled pores that maintain the lipid bilayer in a highly fluidic state and free from frictional interactions with substrate.
Berselli, Guilherme   +4 more
core   +1 more source

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

open access: yesAdvanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan   +6 more
wiley   +1 more source

Lipid raft idea is floated [PDF]

open access: yesThe Journal of Cell Biology, 2006
![][1] Lipids pause in the Golgi before being sorted to distinct destinations. VAN MEER The introduction of a fluorescent lipid probe, specifically fluorescent ceramide, in the mid-1980s ([Lipsky and Pagano, 1983][2]; [Lipsky and Pagano, 1985][3]) gave Gerrit van Meer and Kai ...
openaire   +2 more sources

Synthetic Lethal Therapy Based on Dimorphism for Systemic Infection of Drug‐Resistant Candida albicans

open access: yesAdvanced Science, EarlyView.
To tackle the alarming mortality rate linked to Candida albicans infections, a synthetic lethal strategy precisely aimed at the two distinct forms of this fungus: yeast and hyphae is formulated. Ultimately, through the innovative use of macrophage membranes for drug delivery, the effectiveness of this strategy is substantially boosted while ...
Yang Gao   +12 more
wiley   +1 more source

Atomistic simulations of a multicomponent asymmetric lipid bilayer

open access: yes, 2012
The cell membrane is inherently asymmetric and heterogeneous in its composition, a feature that is crucial for its function. Using atomistic molecular dynamics simulations, the physical properties of a 3-component asymmetric mixed lipid bilayer system ...
Polley, Anirban   +2 more
core   +1 more source

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