Results 81 to 90 of about 639,057 (242)

Role of lipid rafts and GM1 in the segregation and processing of prion protein.

PLoS ONE, 2014
The prion protein (PrPC) is highly expressed within the nervous system. Similar to other GPI-anchored proteins, PrPC is found in lipid rafts, membrane domains enriched in cholesterol and sphingolipids.
Laura Botto, Diana Cunati, Silvia Coco, Silvia Sesana, Alessandra Bulbarelli, Emiliano Biasini, Laura Colombo, Alessandro Negro, Roberto Chiesa, Massimo Masserini, Paola Palestini   +10 more
doaj   +1 more source

Anesthetics interacting with lipid rafts

European Journal of Pharmaceutical Sciences, 2013
The exact mechanism by which anesthetics induce cell membrane-mediated modifications is still an open question. Although the fluidization effect of the anesthetic molecules on the cellular membrane is widely recognized, it is not known if anesthetics show any preference for specific membrane domains, namely the lipid rafts.
Cátia, Bandeiras, Ana Paula, Serro, Konstantin, Luzyanin, Anabela, Fernandes, Benilde, Saramago   +4 more
openaire   +2 more sources

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

Advanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu, Ruijuan Zhang, Yixin Duan, Shuqi Huo, Xiang Zhang, Yibin Xing, Lingjing Ma, Tiran Jiang, Xingyu Chen, Qingmin Sun   +9 more
wiley   +1 more source

Genotype-induced changes in biophysical properties of frontal cortex lipid raft from APP/PS1 transgenic mice

Frontiers in Physiology, 2012
Alterations in the lipid composition of lipid rafts have been demonstrated both in human brain and transgenic mouse models, and it has been postulated that aberrant lipid composition in lipid rafts is partly responsible for neuronal degeneration.
Mario L Diaz, Noemi eFabelo, Raquel eMarin   +2 more
doaj   +1 more source

A sensitive S-Trap-based approach to the analysis of T cell lipid raft proteome

Journal of Lipid Research, 2020
The analysis of T cell lipid raft proteome is challenging due to the highly dynamic nature of rafts and the hydrophobic character of raft-resident proteins.
Cerina Chhuon, Shao-Yu Zhang, Vincent Jung, Daniel Lewandowski, Joanna Lipecka, André Pawlak, Dil Sahali, Mario Ollero, Ida Chiara Guerrera   +8 more
doaj   +1 more source

Association between Tetrodotoxin Resistant Channels and Lipid Rafts Regulates Sensory Neuron Excitability [PDF]

, 2012
PubMed ID: 22870192This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Baker, MD, Alessandro Pristerà (146521), Kenji Okuse (146542), Pristera, A, Mark D Baker, Mark D. Baker (146531), Okuse, K, Kenji Okuse, Alessandro Pristerà   +8 more
core   +2 more sources

Molecular roles of Myo1c function in lipid raft exocytosis. [PDF]

, 2020
Lipid rafts are highly dynamic membrane subdomains enriched in specific protein and lipid components that create specialized 'organizing' platforms essential for an array of important cellular functions.

core   +2 more sources

Ciliary Membrane Lipid Homeostasis in Health and Disease

Advanced Science, EarlyView.
This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...
Zhenzhou Huang, Yuan‐yuan Liu, Hanqi Sun, Peiwei Liu   +3 more
wiley   +1 more source

Toluidine Blue for the Determination of Binding of Anionic Polysaccharides to Lipid Raft Domains by Absorption Spectroscopy

Membranes
The complexes of negatively charged polysaccharides with lipid vesicles have been shown to have applications in medicine, bioremediation, water purification, and construction of nano-biosensors.
Sandra Gębczyńska, Julia Gdowska, Agata Mikos, Iga Gawrońska, Teresa Janas, Aleksander Czogalla, Tadeusz Janas   +6 more
doaj   +1 more source

Lipid raft idea is floated [PDF]

The Journal of Cell Biology, 2006
![][1] Lipids pause in the Golgi before being sorted to distinct destinations. VAN MEER The introduction of a fluorescent lipid probe, specifically fluorescent ceramide, in the mid-1980s ([Lipsky and Pagano, 1983][2]; [Lipsky and Pagano, 1985][3]) gave Gerrit van Meer and Kai ...
openaire   +2 more sources