Results 71 to 80 of about 34,012 (255)
Animal Models and Experimental Medicine, EarlyView.The study employed a four‐tiered strategy: (1) UHPLC‐FTMS profiling of Citrus aurantium honey to characterize its chemical composition; (2) network pharmacology analysis integrating target prediction, protein–protein interaction networks, and KEGG pathway enrichment to identify the Thor1/Nprl2‐TORC1 axis as a key mechanistic pathway; (3) in vitro ...
Wenqi Wan +6 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Haematologica, 2010 Background Expression of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and is decreased by hepcidin. We previously showed that ferroportin is present in specific cell surface domains suggestive of lipid ...
Anne Auriac +2 more
doaj +1 more source
Molecules, 2020 10-Gingerol is a major phenolic lipid found in the rhizomes of ginger (Zingiber officinale). Being amphiphilic in nature, phenolic lipids have the ability to incorporate into cell membranes and modulate membrane properties.
Meran Keshawa Ediriweera +3 more
doaj +1 more source
The Many Faces of Lipid Rafts [PDF]
Biophysical Journal, 2014 Recent experimental observations in raft-forming lipid bilayers demonstrated a phase behavior unsuspected just a few years ago (1,2). Mixtures of Chol (cholesterol) with disordered (unsaturated) and ordered (saturated) phospholipids change their phase behavior from apparently uniform phases to modulated phases to complete phase separation by small ...
openaire +2 more sources
Lipid raft idea is floated [PDF]
The Journal of Cell Biology, 2006 ![][1] Lipids pause in the Golgi before being sorted to distinct destinations. VAN MEER The introduction of a fluorescent lipid probe, specifically fluorescent ceramide, in the mid-1980s ([Lipsky and Pagano, 1983][2]; [Lipsky and Pagano, 1985][3]) gave Gerrit van Meer and Kai ...
openaire +2 more sources
Asia-Pacific Journal of Chemical Engineering, EarlyView.ABSTRACT The global trend toward sustainable and intensified bioprocesses is driving innovation in the design and scalable synthesis of liposomal nanocarriers, a cornerstone of modern drug delivery. For decades, these nanosystems have relied exclusively on polyethylene glycol (PEG) for their sustained circulation in vivo, but they are currently ...
Chandra Has
wiley +1 more source
BMEMat, EarlyView.A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie +12 more
wiley +1 more source
Carbon Innovation, EarlyView.ABSTRACT Antimicrobial peptides (AMPs) are promising alternatives to antibiotics but require precise and costly sequence control for efficacy. Synthetic polymers composed of acrylate and acrylamide offer a simpler and more time‐efficient antibacterial strategy compared to AMPs.
Jooyoung Roh +2 more
wiley +1 more source