Results 31 to 40 of about 75,080 (297)

The Important Role of Lipid Raft-Mediated Attachment in the Infection of Cultured Cells by Coronavirus Infectious Bronchitis Virus Beaudette Strain. [PDF]

open access: yesPLoS ONE, 2017
Lipid raft is an important element for the cellular entry of some viruses, including coronavirus infectious bronchitis virus (IBV). However, the exact role of lipid rafts in the cellular membrane during the entry of IBV into host cells is still unknown ...
Huichen Guo   +10 more
doaj   +1 more source

Lipid Rafts and Pseudotyping [PDF]

open access: yesJournal of Virology, 2001
ABSTRACTSpecific interactions between envelope and core proteins govern the membrane assembly of most enveloped viruses. Despite this, mixed infections lead to pseudotyping, the association of the viral cores of one virus with the envelopes of another. How does this occur?
W F, Pickl   +2 more
openaire   +2 more sources

Hematopoiesis is regulated by cholesterol efflux pathways and lipid rafts: connections with cardiovascular diseases

open access: yesJournal of Lipid Research, 2020
Lipid rafts are highly ordered regions of the plasma membrane that are enriched in cholesterol and sphingolipids and play important roles in many cells.
Pooranee K. Morgan   +3 more
doaj   +1 more source

Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation [PDF]

open access: yes, 2016
Mitochondria-associated membranes (MAMs) are subdomains of the endoplasmic reticulum (ER) that interact with mitochondria. This membrane scrambling between ER and mitochondria appears to play a critical role in the earliest steps of autophagy.
Faggioni, Alberto   +9 more
core   +2 more sources

10-Gingerol Targets Lipid Rafts Associated PI3K/Akt Signaling in Radio-Resistant Triple Negative Breast Cancer Cells

open access: yesMolecules, 2020
10-Gingerol is a major phenolic lipid found in the rhizomes of ginger (Zingiber officinale). Being amphiphilic in nature, phenolic lipids have the ability to incorporate into cell membranes and modulate membrane properties.
Meran Keshawa Ediriweera   +3 more
doaj   +1 more source

Lipid Raft Microdomains [PDF]

open access: yesThe Journal of Experimental Medicine, 2002
Spatiotemporal aspects of filovirus entry and release are poorly understood. Lipid rafts act as functional platforms for multiple cellular signaling and trafficking processes. Here, we report the compartmentalization of Ebola and Marburg viral proteins within lipid rafts during viral assembly and budding.
Sina Bavari   +9 more
openaire   +1 more source

Genotype-induced changes in biophysical properties of frontal cortex lipid raft from APP/PS1 transgenic mice

open access: yesFrontiers in Physiology, 2012
Alterations in the lipid composition of lipid rafts have been demonstrated both in human brain and transgenic mouse models, and it has been postulated that aberrant lipid composition in lipid rafts is partly responsible for neuronal degeneration.
Mario L Diaz   +2 more
doaj   +1 more source

The trafficking and targeting of P2X receptors [PDF]

open access: yes, 2013
The functional expression of P2X receptors at the plasma membrane is dependent on their trafficking along secretory and endocytic pathways. There are seven P2X receptor subunits, and these differ in their subcellular distributions because they have very ...
Murrell-Lagnado, Ruth D   +1 more
core   +3 more sources

Lateral phase separation in mixtures of lipids and cholesterol [PDF]

open access: yes, 2004
In an effort to understand "rafts" in biological membranes, we propose phenomenological models for saturated and unsaturated lipid mixtures, and lipid-cholesterol mixtures.
Bloom M.   +16 more
core   +2 more sources

Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization,secondary mediators, and Rac [PDF]

open access: yes, 2010
The C-type lectin-like receptor 2 (CLEC-2)activates platelets through Src and Syk tyrosine kinases via a single cytoplasmic YxxL motif known as a hem immunoreceptor tyrosine-based activation motif (hemITAM).Here, we demonstrate using sucrose gradient ...
Alice Y. Pollitt   +44 more
core   +1 more source

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