Preparation of fatty acid solutions for investigating lipid signaling, metabolism, and lipid droplets. [PDF]
Zhang S+7 more
europepmc +1 more source
Osmotic stress activates distinct lipid and MAPK signalling pathways in plants [PDF]
Teun Munnik, H.J.G. Meijer
openalex +1 more source
Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer+10 more
wiley +1 more source
Functional regulation of macrophages by Ces1d-mediated lipid signaling in immunometabolism. [PDF]
Shao LJ+12 more
europepmc +1 more source
Epidermal Growth Factor Modulates Palmitic Acid-Induced Inflammatory and Lipid Signaling Pathways in SZ95 Sebocytes. [PDF]
Törőcsik D+8 more
europepmc +1 more source
Eco‐friendly nanowave‐textured implants produced via femtosecond laser fabrication enhance bone regeneration by orchestrating a precise mechanotransduction cascade. This nanotopography directs mesenchymal stem cell alignment and cytoskeletal organization, triggering changes in nuclear shape and chromatin acetylation that prime cells for osteogenesis ...
Bosu Jeong+15 more
wiley +1 more source
Proliferating or Differentiating Stimuli Act on Different Lipid-dependent Signaling Pathways in Nuclei of Human Leukemia Cells [PDF]
Luca M. Neri+6 more
openalex +1 more source
Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh+3 more
wiley +1 more source
Malonyl-CoA Signaling, Lipid Partitioning, and Glucolipotoxicity [PDF]
Marc Prentki+3 more
openalex +1 more source