Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen+9 more
wiley +1 more source
NAAA-regulated lipid signaling in monocytes controls the induction of hyperalgesic priming in mice. [PDF]
Fotio Y+12 more
europepmc +1 more source
Apoptotic Cells Induce Migration of Phagocytes via Caspase-3-Mediated Release of a Lipid Attraction Signal [PDF]
Kirsten Lauber+15 more
openalex +1 more source
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar+6 more
wiley +1 more source
Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis. [PDF]
Sarkar S+24 more
europepmc +1 more source
A genome engineering resource to uncover principles of cellular organization and tissue architecture by lipid signaling. [PDF]
Trivedi D+8 more
europepmc +1 more source
Activating Signal Cointegrator 2 Required for Liver Lipid Metabolism Mediated by Liver X Receptors in Mice [PDF]
Seung‐Whan Kim+11 more
openalex +1 more source
Laser‐Induced Graphene from Waste Almond Shells
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova+9 more
wiley +1 more source
Targeted Expression of the Class II Phosphoinositide 3-Kinase in Drosophila melanogaster Reveals Lipid Kinase-Dependent Effects on Patterning and Interactions with Receptor Signaling Pathways [PDF]
Lindsay K. MacDougall+4 more
openalex +1 more source
Metal Nanoclusters for Cancer Imaging and Treatment
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu+5 more
wiley +1 more source