Results 11 to 20 of about 593,917 (313)

Perspectives of lipid metabolism reprogramming in head and neck squamous cell carcinoma: An overview

Frontiers in Oncology, 2022
Recent studies showed that lipid metabolism reprogramming contributes to tumorigenicity and malignancy by interfering energy production, membrane formation, and signal transduction in cancers. HNSCCs are highly reliant on aerobic glycolysis and glutamine
Xiangwan Miao, Xiangwan Miao, Xiangwan Miao, Beilei Wang, Beilei Wang, Beilei Wang, Kaili Chen, Kaili Chen, Kaili Chen, Rui Ding, Rui Ding, Rui Ding, Jichang Wu, Jichang Wu, Jichang Wu, Yi Pan, Yi Pan, Yi Pan, Peilin Ji, Peilin Ji, Peilin Ji, Bin Ye, Bin Ye, Bin Ye, Mingliang Xiang, Mingliang Xiang, Mingliang Xiang   +26 more
doaj   +1 more source

CDP-Diacylglycerol Synthases (CDS): Gateway to Phosphatidylinositol and Cardiolipin Synthesis

Frontiers in Cell and Developmental Biology, 2020
Cytidine diphosphate diacylglycerol (CDP-DAG) is a key intermediate in the synthesis of phosphatidylinositol (PI) and cardiolipin (CL). Both PI and CL have highly specialized roles in cells.
Nicholas J. Blunsom, Shamshad Cockcroft
doaj   +1 more source

Shelf-life of Moroccan prickly pear (Opuntia ficus-indica) and argan (Argania spinosa) oils: a comparative study

Grasas y Aceites, 2021
Cactus seed oil is gaining considerable popularity in the cosmetic industry. To estimate cactus seed oil’ industrial as well as domestic ease of use, we investigated the oxidative stability of Moroccan cactus seed oil under accelerated aging conditions ...
S. Gharby, D. Guillaume, I. Nounah, H. Harhar, A. Hajib, B. Matthäus, Z. Charrouf   +6 more
doaj   +1 more source

New Driver for Lipid Synthesis [PDF]

Cell, 2011
Cholesterol regulates activation of sterol regulatory element-binding protein (SREBP) through a classic feedback loop. Walker et al. (2011) extend the regulatory inputs governing SREBP activity to include an independent loop modulated by phosphatidylcholine (PC) and cellular methylation capacity.
Houten, Sander M., Argmann, Carmen A.
openaire   +2 more sources

Activity Evaluation of Alcohol Extract of Ginseng-Clove in Inhibiting Lipid Synthesis of Mortierella alpina

Shipin gongye ke-ji, 2022
The inhibitory of lipid synthesis by the alcohol extract of ginseng-clove was explored and its mechanism was preliminarily studied. A lipid screening model of Mortierella alpina (MA) which is rich in fatty acids was established, and 2,3,5 ...
Weifeng NI, Daqing ZHAO, Yiyu NI, Zhulin BAI, Siming WANG   +4 more
doaj   +1 more source

Knocking out central metabolism genes to identify new targets and alternating substrates to improve lipid synthesis in Y. lipolytica

Frontiers in Bioengineering and Biotechnology, 2023
Introduction: Systematic gene knockout studies may offer us novel insights on cell metabolism and physiology. Specifically, the lipid accumulation mechanism at the molecular or cellular level is yet to be determined in the oleaginous yeast Y.
Jiang Zhu, Yang Gu, Yang Gu, Yijing Yan, Jingbo Ma, Jingbo Ma, Xiaoman Sun, Peng Xu, Peng Xu, Peng Xu   +9 more
doaj   +1 more source

Active components to regulate lipid synthesis and inflammatory cascade in cultivated human SZ95 sebocytes [PDF]

, 2009
The aim of this work was to search for new active compounds which regulate lipid synthesis in vitro in SZ95 sebocytes. More than 200 extracts and fractions derived from plants, microorganisms, Bothrops moojeni snake venom as well as peptides were ...
Schagen, Silke Karin
core   +1 more source

Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects [PDF]

, 2004
Background/Aims: Ursodeoxycholic acid ( UDCA) decreases biliary secretion of cholesterol and is therefore used for the dissolution of cholesterol gallstones.
Thiessen, K., Parhofer, K. G., Fischer, S., Sauter, G. H., Jungst, D., Jungst, C.   +5 more
core   +1 more source

Investigating the Effects of Statins on Cellular Lipid Metabolism Using a Yeast Expression System [PDF]

, 2009
In humans, defects in lipid metabolism are associated with a number of severe diseases such as atherosclerosis, obesity and type II diabetes. Hypercholesterolemia is a primary risk factor for coronary artery disease, the major cause of premature deaths
Zimnicka, Magdalena, Joanna Kaminska, Burzynska, Beata, Kania Magdalena, Wysocka-Kapcinska, Monika, Beata Burzynska, Witold Danikiewicz, Danikiewicz Witold, Plochocka, Danuta, Leszczynska, Agata, Leszczynska Agata, Zimnicka Magdalena, Danikiewicz, Witold, Wysocka-Kapcinska Monika, Magdalena Kania, Kiliszek Marek, Marek Kiliszek, Kaminska Joanna, Agata Leszczynska, Danuta Plochocka, Magdalena Zimnicka, Kaminska, Joanna, Plochocka Danuta, Szkopinska, Anna, Anna Szkopinska, Kania, Magdalena, Kiliszek, Marek, Szkopinska Anna, Monika Wysocka-Kapcinska, Burzynska Beata   +29 more
core   +1 more source

Antigen-presentation of non-peptidic antigens lipid trafficking and loading [PDF]

, 2010
T cells recognize a broad variety of antigens, including peptides, lipids and non-peptidic phosphorylated metabolites. Clarification of the rules rendering non-peptidic molecules immunogenic is essential to understand and to influence the reactions of ...
Cavallari, Marco F.
core   +1 more source