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Structural basis of lipid transfer by a bridge-like lipid-transfer protein

Nature
Bridge-like lipid-transport proteins (BLTPs) are an evolutionarily conserved family of proteins that localize to membrane-contact sites and are thought to mediate the bulk transfer of lipids from a donor membrane, typically the endoplasmic reticulum, to an acceptor membrane, such as that of the cell or an organelle1.
Yunsik Kang   +6 more
openaire   +2 more sources

Lipid exchange and transfer between biological lipid-protein structures

Progress in Lipid Research, 1978
Abstract The dynamic state of membrane and lipoprotein lipids is all the more impressive when the complexity of lipoprotein and membrane structure is considered. For as long as such a ubiquitous and easily demonstrable process has been studied, the mechanism(s) of lipid exchange is still unknown. Is a direct contact between lipoproteins and membranes
openaire   +2 more sources

Phospholipid transfer protein in lipid metabolism

Current Opinion in Lipidology, 2000
Phospholipid transfer protein (PLTP) is one of the main modulators of plasma HDL size and composition. The publications discussed in the present review have substantially increased our knowledge on the physiological importance of PLTP-mediated phospholipid transfer, especially between triglyceride-rich lipoproteins and HDL. Furthermore, novel data have
J, Huuskonen, C, Ehnholm
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Lipid Synthesis and Transfer

1990
The high interest of the studies of plant lipids is justified by their various roles in plant growth and development: i/ lipids play important structural roles since they are major constituents of cell membranes ; ii/ lipids can control, in some extent, the activity of membrane-bound enzymes ; iii/ various membrane proteins are esterified at their N ...
Jean-Claude Kader, Pascal Laurent
openaire   +1 more source

Reducible cationic lipids for gene transfer

Biochemical Journal, 2001
One of the main challenges of gene therapy remains the increase of gene delivery into eukaryotic cells. We tested whether intracellular DNA release, an essential step for gene transfer, could be facilitated by using reducible cationic DNA-delivery vectors. For this purpose, plasmid DNA was complexed with cationic lipids bearing a disulphide bond.
B, Wetzer   +6 more
openaire   +2 more sources

Cationic lipids used in gene transfer

Advanced Drug Delivery Reviews, 1997
Gene transfer could represent an important advance in the treatment of both genetic and acquired diseases. Cationic lipid-mediated gene transfer have advantages over viral gene transfer because they are non-immunogenic, they are easy to produce and they are not oncogenic. The major limitation of cationic lipid-mediated gene transfer is its inefficiency.
openaire   +2 more sources

Energy transfer in black lipid membranes

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1972
This paper reports on energy transfer between three pairs of pigments which were incorporated into black lipid membranes: 1. 1. Chlorophyll b and chlorophyll a. 2. 2. p-bis[2-(4-Methyl-5-phenyloxazoyl)]benzene (dimethyl-POPOP) and chlorophyll a. 3. 3. 1,6-Diphenyl-1,3,5-hexatriene (DPH) and chlorophyll b.
openaire   +2 more sources

Regulation of phospholipid distribution in the lipid bilayer by flippases and scramblases

Nature Reviews Molecular Cell Biology, 2023
Shigekatzu Nagata
exaly  

Lipid nanoparticles for mRNA delivery

Nature Reviews Materials, 2021
Xucheng Hou   +2 more
exaly  

Lipid biomarkers: molecular tools for illuminating the history of microbial life

Nature Reviews Microbiology, 2021
Roger Everett Summons   +2 more
exaly  

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