Results 21 to 30 of about 611,612 (297)
Incorporation of cytochrome oxidase into cardiolipin bilayers and induction of nonlamellar phases. [PDF]
, 1990 Cytochrome oxidase from beef heart has been lipid-substituted with beef heart cardiolipin. The lipid phase behavior and protein aggregation state of the reconstituted complexes have been studied with 31P NMR, freeze-fracture electron microscopy, and ...
Knowles, P., Marsh, D., Powell, G.
core +2 more sources
Achiral dye/surfactant heteroaggregates for chiral sensing of phosphocholines [PDF]
, 2015 An investigation, based on absorption and circular dichroism spectroscopy, was carried out on assemblies formed in water upon the interaction of heteroaggregates, composed of dyes (Congo Red or Evans Blue) and cetyltrimethylammonium bromide (CTAB), with ...
Altieri, Barbara +4 more
core +1 more source
Journal of Lipid Research, 2006 We have identified a series of potent cholesteryl ester transfer protein (CETP) inhibitors, one member of which, torcetrapib, is undergoing phase 3 clinical trials.
Ronald W. Clark +3 more
doaj +1 more source
μ-calpain binds to lipid bilayers via the exposed hydrophobic surface of its Ca2+-activated conformation [PDF]
, 2006 μ- and m-calpain are cysteine proteases requiring micro- and millimolar Ca2+ concentrations for their activation in vitro. Among other mechanisms, interaction of calpains with membrane phospholipids has been proposed to facilitate their activation by ...
Fernández-Montalván, Amaury +5 more
core +2 more sources
Frontiers in Behavioral Neuroscience, 2018 Vitamin E, the most important lipophilic radical scavenging antioxidant in vivo, has a pivotal role in brain. In an earlier study, we observed that adult mice with a defect in the gene encoding plasma phospholipid transfer protein (PLTP) display a ...
Catherine M. Desrumaux +25 more
doaj +1 more source
Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex
eLife, 2020 Coordinated assembly and disassembly of integrin-mediated focal adhesions (FAs) is essential for cell migration. Many studies have shown that FA disassembly requires Ca2+ influx, however our understanding of this process remains incomplete. Here, we show
Ryan S D'Souza +9 more
doaj +1 more source
Quantitative Models of Lipid Transfer and Membrane Contact Formation
Contact, 2022 Lipid transfer proteins (LTPs) transfer lipids between different organelles, and thus play key roles in lipid homeostasis and organelle dynamics. The lipid transfer often occurs at the membrane contact sites (MCS) where two membranes are held within 10 ...
Yongli Zhang +3 more
doaj +1 more source
Ligand and membrane-binding behavior of the phosphatidylinositol transfer proteins PITPα and β [PDF]
, 2016 Phosphatidylinositol transfer proteins (PITPs) are believed to be lipid transfer proteins due to their ability to transfer either PI or PC between membrane compartments in vitro.
Atkinson, J +3 more
core +1 more source
Recent Advances in Membrane Shaping for Plant Autophagosome Biogenesis
Frontiers in Plant Science, 2020 Autophagy is an intracellular degradation process, which is highly conserved in eukaryotes. During this process, unwanted cytosolic constituents are sequestered and delivered into the vacuole/lysosome by a double-membrane organelle known as an ...
Cheuk-Ling Wun +2 more
doaj +1 more source
Coming together to define membrane contact sites. [PDF]
, 2019 Close proximities between organelles have been described for decades. However, only recently a specific field dealing with organelle communication at membrane contact sites has gained wide acceptance, attracting scientists from multiple areas of cell ...
De Matteis, Maria Antonietta +14 more
core +7 more sources