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Crystal Structure of the ORP8 Lipid Transport ORD Domain: Model of Lipid Transport [PDF]

open access: yesCells, 2023
ORPs are lipid-transport proteins belonging to the oxysterol-binding protein family. They facilitate the transfer of lipids between different intracellular membranes, such as the ER and plasma membrane.
Andrea Eisenreichova   +6 more
doaj   +5 more sources

Quantitative Imaging of Lipid Transport in Mammalian Cells [PDF]

open access: yesNature
Eukaryotic cells produce over 1,000 different lipid species that tune organelle membrane properties, control signalling and store energy1,2. How lipid species are selectively sorted between organelles to maintain specific membrane identities is largely ...
Katelyn C Cook   +2 more
exaly   +4 more sources

Pharmacological interventions for lipid transport disorders [PDF]

open access: yesFrontiers in Neuroscience, 2023
The recent discovery that defects in inter-organelle lipid transport are at the heart of several neurological and neurodegenerative disorders raises the challenge of identifying therapeutic strategies to correct lipid transport defects.
Aaron M. Neiman
doaj   +2 more sources

QingGan LiDan capsules improved alcoholic liver injury by regulating liver lipid transport and oxidative stress in mice [PDF]

open access: yesFrontiers in Pharmacology
BackgroundThe QingGan LiDan capsule (QGLD) consists of five traditional Chinese herbs, which have been used for hepatobiliary diseases such as jaundice.
Zhiwen Fu   +19 more
doaj   +2 more sources

Lipid Transport Across Bacterial Membranes [PDF]

open access: yesAnnual Review of Cell and Developmental Biology, 2022
Damian C Ekiert   +2 more
exaly   +2 more sources

An Updated Perspective on the Dual-Track Model of Enterocyte Fat Metabolism

open access: yesJournal of Lipid Research, 2022
The small intestinal epithelium has classically been envisioned as a conduit for nutrient absorption, but appreciation is growing for a larger and more dynamic role for enterocytes in lipid metabolism.
Joshua R. Cook   +2 more
doaj   +1 more source

Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands

open access: yesJournal of Lipid Research, 2021
Present in the small intestine, cellular retinol binding protein 2 (CRBP2) plays an important role in the uptake, transport, and metabolism of dietary retinoids.
Josie A. Silvaroli   +6 more
doaj   +1 more source

Expression of genes related to lipid transport in meat-type ducks divergent for low or high residual feed intake [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2020
Objective This study examined the effects of divergence in residual feed intake (RFI) on expression profiles of key genes related to lipid transport in the liver and duodenal epithelium and their associations with feed efficiency traits in meat-type ...
Sihua Jin   +6 more
doaj   +1 more source

P-Type ATPase Apt1 of the Fungal Pathogen Cryptococcus neoformans Is a Lipid Flippase of Broad Substrate Specificity

open access: yesJournal of Fungi, 2021
Lipid flippases of the P4-ATPase family are ATP-driven transporters that translocate lipids from the exoplasmic to the cytosolic leaflet of biological membranes.
Lyubomir Dimitrov Stanchev   +9 more
doaj   +1 more source

Osh6 Revisited: Control of PS Transport by the Concerted Actions of PI4P and Sac1 Phosphatase

open access: yesFrontiers in Molecular Biosciences, 2021
Osh6, a member of the oxysterol-binding protein–related protein (ORP) family, is a lipid transport protein that is involved in the transport of phosphatidylserine (PS) between the endoplasmic reticulum (ER) and the plasma membrane (PM).
Andrea Eisenreichova   +3 more
doaj   +1 more source

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