Results 181 to 190 of about 3,299,584 (293)

Leicester Transport Department, Humberstone Gate, 1970

, 1970
View of the roofs of the Leicester Transport Department ...
Calow, Dennis;
core  

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source

Kaempferol inhibits <i>Chlamydia psittaci</i> proliferation by blocking lipid transport and RB-EB differentiation. [PDF]

Front Microbiol
Lin Y, Jiang Y, Zhang S, Zhang Z, Liu S, Lin J, Chen X, Zhang Y, Yu Y, Wei W, OuYang X, Huang X, Song Y, Jiao J.   +13 more
europepmc   +1 more source

Regulation of cellular cholesterol distribution via non-vesicular lipid transport at ER-Golgi contact sites. [PDF]

Nat Commun, 2023
Naito T, Yang H, Koh DHZ, Mahajan D, Lu L, Saheki Y.   +5 more
europepmc   +1 more source

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

Advanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol, Bochuan Hu, Eduard O. Bobylev, Martina Farber, Petrus C. M. Laan, Thomas J. F. Kock, Bauke Fontein, Johanna Erbani, Oscar Escalona‐Rayo, Seline S. Roose, Tom Keijer, Gabriel Forn‐Cuní, B. Ewa Snaar‐Jagalska, Leila Akkari, Joost N. H. Reek, Alexander Kros, Dennis Aschmann   +16 more
wiley   +1 more source

Lipid Transport by Candida albicans Dnf2 Is Required for Hyphal Growth and Virulence. [PDF]

Infect Immun, 2022
Jain BK, Wagner AS, Reynolds TB, Graham TR.   +3 more
europepmc   +1 more source

A Critical Call for Mechanistic Investigations of Metal‐Bacteria Interactions

Advanced Materials, EarlyView.
It is well established that the antibacterial properties of metals have tremendous importance for bioengineering applications. What is not as appreciated, however, is the reproducibility crisis in this field's vast literature. In this perspective, we highlight this reproducibility problem, discuss its sources, and suggest solutions towards focused ...
J. Rackwitz, A. Bandyopadhyay, S. Belkin, S. Bose, N. Eliaz, J. L. Gilbert, T. C. Lowe, F. Mücklich, R. J. Turner, C. C. Tasan   +9 more
wiley   +1 more source

glorund functions in the <i>Drosophila</i> intestine to regulate triglyceride storage and the expression of lipid transport protein genes. [PDF]

MicroPubl Biol
Voskoboynikov R, DiAngelo JR.
europepmc   +1 more source

Ceramide-1-phosphate transfer protein enhances lipid transport by disrupting hydrophobic lipid-membrane contacts. [PDF]

PLoS Comput Biol, 2023
Rogers JR, Geissler PL.
europepmc   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source