Results 191 to 200 of about 3,299,584 (293)

Lipid Transport in Brown Adipocyte Thermogenesis. [PDF]

Front Physiol, 2021
Wade G, McGahee A, Ntambi JM, Simcox J.
europepmc   +1 more source

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source

A Fluorescence-Based Flippase Assay to Monitor Lipid Transport by Drs2-Cdc50. [PDF]

Bio Protoc
Van Der Linden IM, Herrera SA, Montigny C, Lenoir G, Pomorski TG, Uzun HD.   +5 more
europepmc   +1 more source

Lamp1 mediates lipid transport, but is dispensable for autophagy in Drosophila. [PDF]

Autophagy, 2022
Chaudhry N, Sica M, Surabhi S, Hernandez DS, Mesquita A, Selimovic A, Riaz A, Lescat L, Bai H, MacIntosh GC, Jenny A.   +10 more
europepmc   +1 more source

“Activation‐Resistance Elimination” Regulation by Lanthanide/Transition Metal Ion‐Coordinated Nanostructures Intensifies Cuproptosis and Tumor Immunotherapy

Advanced Materials, EarlyView.
The lanthanide/transition metal ion coordination nanoparticles, La‐Cu@Lap/IWR‐1, with optimized coordination, have been proven to achieve remarkable results in realizing comprehensive tumor cuproptosis through efficient cuproptosis activation and multidimensional resistance elimination, thereby synchronously realizing the synergistic antitumor effects ...
Junrong Wang, Mengqian Xu, Huaping Zhao, Yulin Xie, Guoqing Zhu, Haoze Li, Qianqian Sun, Yong Lei, Chunxia Li   +8 more
wiley   +1 more source

Increased expression of CD36 and CD163 in clear cell renal cell carcinoma suggests an association between lipid transport and an "M2-like" macrophage phenotype. [PDF]

Front Immunol
Bouraoui Y, Said R, Bruss C, Martowicz A, Wagner K, Weber F, Engelmann SU, Kaelble S, Höring M, Liebisch G, Mayr R, Siska PJ.   +11 more
europepmc   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

Tissue-specific SEC31A alternative splicing is regulated by RBM47 and controls lipid transport. [PDF]

RNA
Ostwaldt F, Plößner S, Dimos-Röhl B, Preussner M, Heyd F.   +4 more
europepmc   +1 more source

pH‐Responsive Synthetic Cells for Programmable In Situ Protein Synthesis and Release

Advanced Materials, EarlyView.
A synthetic cell is engineered to convert environmental acidification into nucleic acid signaling that activates protein synthesis. By coupling proton‐channel sensing, pH‐responsive DNA transduction, and toehold‐regulated translation, the platform enables acid‐triggered protein production within hydrogel‐embedded synthetic cells.
Sung‐Won Hwang, Yudan Li, Alexander A. Green, Allen P. Liu   +3 more
wiley   +1 more source

APOE-mediated lipid transport prevents C1q-related synaptic loss after spinal cord injury via attenuating macrophage lipid stress. [PDF]

J Neuroinflammation
Mulat Y, Ren Z, Nong C, Fu C, Huo Y, Zhao M, Dai Y, Chen C, Wang P, Wang R, Zhang H, Hu Y, Lai P, Guo R, Jiang D, Peng Y, Lin H.   +16 more
europepmc   +1 more source