Results 51 to 60 of about 19,214 (276)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Swiss Medical Weekly, 2014 PRINCIPLES: As a result of the relatively low sensitivity of coronary risk charts, such as the Swiss coronary risk calculator (Arbeitsgruppe Lipide und Atherosklerose, AGLA), for detecting subjects with future myocardial infarction, the performance of ...
Michel Romanens +4 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Semiautomatic Method for the Separation and Determination of Total Triiodthyronine and Thyroxine in Serum [PDF]
, 1972 A semiautomatic procedure is presented for the separate determination of total T3 and T4 in serum in approximately 10 hrs simultaneously in 25 samples.
Horn, K. +2 more
core +3 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Dislipidemiile în asociere cu alți factori de risc în pancreatita cronică
Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2019 Studiul a fost unul prospectiv și a inclus 30 de pacienți cu pancreatită cronică (PC), tratați în secţia de gastroenterologie a SCM ,,Sf. Arh. Mihail”, la care s-a evaluat statusul lipidic în raport cu alți factori de risc.
Rodica Bugai +5 more
doaj
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Einfluß von Okklusionseffekten auf die Epikutantestung mit Natriumlaurylsulfat [PDF]
, 2005 In der Bestimmung der Hautempfindlichkeit bei Epikutantestungen mit dem anionischen Detergens Natriumlaurylsulfat (NLS) werden verschiedene nicht-invasive hautphysiologische Meßverfahren eingesetzt.
Friebe, Katharina +1 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source