Results 61 to 70 of about 19,214 (276)

Histochemical and immunohistochemical analysis of ruptured atherosclerotic abdominal aortic aneurysm wall [PDF]

open access: yes, 2010
Background/Aim. The main complication of the atherosclerotic abdominal aortic aneurism (AAA) is her rupture that begins with lesion in intima and rupture.
Aleksić Aleksandar   +12 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

INFLUENŢA EXTRACTULUI DE AMINOACIZI ŞI OLIGOPEPTIDE DE ORIGINE CIANOBACTERIANĂ DIN BIOMASA SPIRULINA (ARTHROSPIRA) PLATENSIS ASUPRA CREŞTERII ŞI LIPIDOGENEZEI TULPINII STREPTOMYCES FRADIAE CNMN-Ac-11

open access: yesStudia Universitatis Moldaviae: Stiinte reale si ale naturii, 2017
A fost studiată capacitatea tulpinii Streptomyces fradiae CNMN-Ac-11, izolată din solurile Părții Centrale a Republicii Moldova, de a acumula biomasă și sinteza lipidelor în dependență de compoziția mediului nutritiv.
USM ADMIN
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Molecular simulations of lipid bilayers in interactions with gold nanoparticles [PDF]

open access: yes, 2016
Gold nanoparticles are interesting candidates for medical applications like markers in imaging methods and targeted drug delivery, especially to cancer cells.
Pfeiffer, Tobias
core  

Erzeugung und Charakterisierung zielgerichteter liposomaler Trägersysteme für die Tumortherapie [PDF]

open access: yes, 2005
Das Ziel der vorliegenden Arbeit war es, drei neue liposomale Systeme für die zielgerichtete Tumortherapie zu entwickeln. Dafür wurden liposomale Oberflächen mit Zielsteuerungsmotiven, die mittels der Phage-Display-Technologie erzeugt wurden, modifiziert.
Hölig, Peter   +1 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Hyperhomocysteinemia - an additional risk factor of thrombosis in systemic lupus erythematosus and antiphospholipid syndrome

open access: yesНаучно-практическая ревматология, 2003
Objective. To assess homocystein (HC) level in systemic lupus erythematosus (SLE) with antiphospholipid syndrome (APS) and its relation to thrombosis development and blood lipide spectrum disturbances. Material and methods. 32 pts (12 male and 20 female)
I. E. Shirokova, T M Reshelnyak
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Oksidacijski stres i lipidna peroksidacija – od molekularnih mehanizama do klinike

open access: yesLiječnički vjesnik
Pojam oksidacijski stres podrazumijeva procese stvaranja suviška reaktivnih kisikovih tvari (ROS) u odnosu na mogućnosti nadzora ROS-a od strane stanica i organizma putem antioksidansa.
Suzana Borović Šunjić   +8 more
doaj   +1 more source

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