Results 31 to 40 of about 31,402 (296)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Techniques conventionelles et innovantes, et solvants alternatifs pour l’extraction des lipides de micro-organismes

Oilseeds and fats, crops and lipids, 2013
Cette revue propose un panorama complet des connaissances actuelles sur les microorganismes sources de lipides utilisés comme biocarburant. Elle fournit les éléments nécessaires à la compréhension de la culture des microorganismes ...
Abert Vian Maryline, Dejoye Tanzi Céline, Chemat Farid   +2 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Influence des protéines et des lipides chez le diabétique de type 1: un outil pour la pratique : travail de Bachelor [PDF]

, 2016
Introduction : Actuellement, la méthode du calcul des hydrates de carbone pratiquée à travers l’insulinothérapie est la méthode de référence dans la prise en charge du diabète de type 1 (DT1) pour déterminer la dose d’insuline prandiale.
Aebi, Anouk, Ansermet, Olivia, Kehl Dubois, Corinne   +2 more
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

LIPIDES DES PLANTES Symposium « Lipides des plantes et oxylipines » : compte rendu et mise en place d’un réseau lipides des plantes

Oléagineux, Corps gras, Lipides, 2001
Un colloque sur les lipides de plantes et les oxylipines s’est tenu à Strasbourg les 10 et 11 juillet 2001, dans le cadre des Journées de la Société Française de Physiologie Végétale. Plus de 85 chercheurs ont participé à ce colloque et 45 communications
Arondel Vincent, Miquel Martine, Blee Elizabeth   +2 more
doaj   +1 more source

Changes in proximate composition and oil characteristics during flaxseed development

Grasas y Aceites, 2014
Atmospheric Pressure Photoionization-Mass Spectrometry (APPI-MS) and High Performance Liquid Chromatography (HPLC) are the two analytical methods that were used to characterize Triacylglycerols (TAGs) during flaxseed development.
W. Herchi, S. Bahashwan, H. Trabelsi, S. Boukhchina, H. Kallel, S. Rochut, C. Pepe   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Quelques éléments marquants de la 107ème réunion annuelle de l’AOCS (Salt Lake City, 1–4 mai 2016)

Oilseeds and fats, crops and lipids, 2016
La 107ème réunion annuelle de l’AOCS s’est tenue à Salt Lake City (USA) du 1 au 4 mai 2016. Comme à son habitude, ce congrès a balayé l’ensemble des domaines de la recherche concernant de près ou de loin les lipides avec pas
Bogaert Laurine, Deyrieux Charlotte, Subileau Maeva, Durand Erwann, Fine Frédéric   +4 more
doaj   +1 more source