Results 1 to 10 of about 24,383 (256)

Characterizing the breast cancer lipidome and its interaction with the tissue microbiota [PDF]

Communications Biology, 2021
Giallourou, Urbaniak et al. investigated the lipidome and microbiome of breast tissues adjacent to breast tumors and control, healthy breast tissue, by examining both bacterial colonization and lipid metabolism.
Natasa Giallourou, Camilla Urbaniak, Scarlett Puebla-Barragan, Panagiotis A. Vorkas, Jonathan R. Swann, Gregor Reid   +5 more
doaj   +2 more sources

Uncovering the complex genetic architecture of human plasma lipidome using machine learning methods

Scientific Reports, 2023
Genetic architecture of plasma lipidome provides insights into regulation of lipid metabolism and related diseases. We applied an unsupervised machine learning method, PGMRA, to discover phenotype-genotype many-to-many relations between genotype and ...
Miikael Lehtimäki, Binisha H. Mishra, Coral Del-Val, Leo-Pekka Lyytikäinen, Mika Kähönen, C. Robert Cloninger, Olli T. Raitakari, Reijo Laaksonen, Igor Zwir, Terho Lehtimäki, Pashupati P. Mishra   +10 more
doaj   +1 more source

Single-cell lipidomics enabled by dual-polarity ionization and ion mobility-mass spectrometry imaging

Nature Communications, 2023
Single-cell (SC) analysis provides unique insight into individual cell dynamics and cell-to-cell heterogeneity. Here, we utilize trapped ion mobility separation coupled with dual-polarity ionization mass spectrometry imaging (MSI) to enable high ...
Hua Zhang, Yuan Liu, Lauren Fields, Xudong Shi, Penghsuan Huang, Haiyan Lu, Andrew J. Schneider, Xindi Tang, Luigi Puglielli, Nathan V. Welham, Lingjun Li   +10 more
doaj   +1 more source

Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl-, and phosphoglycerol dipeptide lipid families

Journal of Lipid Research, 2023
Porphyromonas gingivalis, like other members of the phylum Bacteroidetes (synonym Bacteroidota), synthesizes several classes of dihydroceramides and peptidolipids.
Brian A. Kleiboeker, Cheryl Frankfater, Mary E. Davey, Fong-Fu Hsu   +3 more
doaj   +1 more source

Mitochondrial DNA affects metabolome, lipidome, and proteome in a sex specific manner in old heterogenous rats [PDF]

Innov Aging
Hoang Van Nguyen, Chloe L. Fender, Manuel Garcia-Jaramillo, A. I. Nagib, Norman G. Hord, Steven N. Austad, Arlan Richardson, Michael B. Stout   +7 more
europepmc   +2 more sources

Changes in the lipidome of water buffalo milk during intramammary infection by non-aureus Staphylococci

Scientific Reports, 2022
This study aimed to determine the lipidome of water buffalo milk with intramammary infection (IMI) by non-aureus staphylococci (NAS), also defined as coagulase-negative staphylococci, using an untargeted lipidomic approach.
Fabrizio Ceciliani, Matteo Audano, Maria Filippa Addis, Nico Mitro, Cristina Lecchi, Morteza H. Ghaffari, Mariangela Albertini, Esterina De Carlo, Domenico Vecchio, Gabriele Di Vuolo, Giovanna Cappelli, Francesco Tangorra, Renata Piccinini, Valerio Bronzo, Donatella Caruso   +14 more
doaj   +1 more source

The LUX Score: A Metric for Lipidome Homology. [PDF]

PLoS Computational Biology, 2015
A lipidome is the set of lipids in a given organism, cell or cell compartment and this set reflects the organism's synthetic pathways and interactions with its environment.
Chakravarthy Marella, Andrew E Torda, Dominik Schwudke   +2 more
doaj   +1 more source

Impacts of Formula Supplemented with Milk Fat Globule Membrane on the Neurolipidome of Brain Regions of Piglets

Metabolites, 2022
The milk fat globule membrane (MFGM) appears to play an important role in infant neurocognitive development; however, its mechanism(s) of action remains unclear.
Karl Fraser, Leigh Ryan, Ryan N. Dilger, Kelly Dunstan, Kelly Armstrong, Jason Peters, Hedley Stirrat, Neill Haggerty, Alastair K. H. MacGibbon, James Dekker, Wayne Young, Nicole C. Roy   +11 more
doaj   +1 more source

Comparative transcriptome and lipidome reveal that a low K+ signal effectively alleviates the effect induced by Ca2+ deficiency in cotton fibers

Journal of Integrative Agriculture, 2023
Calcium (Ca2+) plays an important role in determining plant growth and development because it maintains cell wall and membrane integrity. Therefore, understanding the role of Ca2+ in carbon and lipid metabolism could provide insights into the dynamic ...
Kai GUO, Wei GAO, Tao-rui ZHANG, Zu-ying WANG, Xiao-ting SUN, Peng YANG, Lu LONG, Xue-ying LIU, Wen-wen WANG, Zhong-hua TENG, Da-jun LIU, De-xin LIU, Li-li TU, Zheng-sheng ZHANG   +13 more
doaj   +1 more source

Comprehensive Metabolic Profiling of Inflammation Indicated Key Roles of Glycerophospholipid and Arginine Metabolism in Coronary Artery Disease

Frontiers in Immunology, 2022
BackgroundSystemic immune inflammation is a key mediator in the progression of coronary artery disease (CAD), concerning various metabolic and lipid changes. In this study, the relationship between the inflammatory index and metabolic profile in patients
Qian Zhu, Qian Zhu, Yonglin Wu, Jinxia Mai, Gongjie Guo, Gongjie Guo, Jinxiu Meng, Xianhong Fang, Xiaoping Chen, Chen Liu, Shilong Zhong, Shilong Zhong, Shilong Zhong, Shilong Zhong   +13 more
doaj   +1 more source