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Current Opinion in Endocrinology, Diabetes & Obesity, 2021
Purpose of review Multiple studies have shown a strong association between lipids and diabetes. These are usually described through the effects of cholesterol content of lipid particles and in particular low-density lipoprotein.
Eun Ji, Kim +2 more
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Purpose of review Multiple studies have shown a strong association between lipids and diabetes. These are usually described through the effects of cholesterol content of lipid particles and in particular low-density lipoprotein.
Eun Ji, Kim +2 more
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Prostaglandins & Other Lipid Mediators, 2005
Lipidomics the systematic decoding of lipid-based information in biosystems is comprised of identification and profiling of lipids and lipid-derived mediators. As practiced today, lipidomics can be subdivided into architecture/membrane-lipidomics and mediator-lipidomics. The mapping of structural components and their relation to cell activation as well
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Lipidomics the systematic decoding of lipid-based information in biosystems is comprised of identification and profiling of lipids and lipid-derived mediators. As practiced today, lipidomics can be subdivided into architecture/membrane-lipidomics and mediator-lipidomics. The mapping of structural components and their relation to cell activation as well
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Profiling the Mammalian Lipidome by Quantitative Shotgun Lipidomics
2023The emerging field of lipidomics presents the systems biology approach to identify and quantify the full lipid repertoire of cells, tissues, and organisms. The importance of the lipidome is demonstrated by a number of biological studies on dysregulation of lipid metabolism in human diseases such as cancer, diabetes, and neurodegenerative diseases ...
Mads Møller, Foged +2 more
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Metabolomics, Lipidomics, and Immunometabolism
2021Metabolomics, lipidomics, and the study of cellular metabolism are gaining increasing interest particularly in the field of immunology, since the activation and effector functions of immune cells are profoundly controlled by changes in cellular metabolic asset.
Carbone F. +8 more
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Shotgun lipidomics: multidimensional MS analysis of cellular lipidomes
Expert Review of Proteomics, 2005Shotgun lipidomics, comprised of intrasource separation, multidimensional mass spectrometry and computer-assisted array analysis, is an emerging powerful technique in lipidomics. Through effective intrasource separation of predetermined groups of lipid classes based on their intrinsic electrical propensities, analyses of lipids from crude extracts of ...
Xianlin, Han, Richard W, Gross
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Lipidomics of Alzheimer’s Disease
Bioanalysis, 2014Alzheimer's disease (AD) is a progressive brain disease that leads to an irreversible loss of neurons and cognition. It is the most common cause of dementia and can be considered as a major public health problem. At the histological level, AD is characterized by senile plaques and neurofibrillary tangles.
Touboul, David, Gaudin, Mathieu
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2007
Lipids are recognized as key participants in the regulation and control of cellular function, having important roles in signal transduction processes. The diversity in lipid chemical structure presents a challenge for establishing practical methods to generate and manage high volumes of complex data that translate into a snapshot of cellular lipid ...
Eoin, Fahy +8 more
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Lipids are recognized as key participants in the regulation and control of cellular function, having important roles in signal transduction processes. The diversity in lipid chemical structure presents a challenge for establishing practical methods to generate and manage high volumes of complex data that translate into a snapshot of cellular lipid ...
Eoin, Fahy +8 more
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Quantitative Profiling of Lysosomal Lipidome by Shotgun Lipidomics
2017Recent studies have illuminated novel roles of lysosomes that go far beyond simple catabolism and function in the coordination of cellular metabolism and signaling. Promising therapeutic strategies emerge from knowledge in the molecular mechanisms and physiological roles of lipid metabolism in lysosomes.
Mesut Bilgin +3 more
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