Results 181 to 190 of about 41,885 (269)

Scalp Microbiome Alterations in Androgenetic Alopecia: Patterns and Emerging Mechanistic Insights

International Journal of Dermatology, EarlyView.
Summary of the microbiome‐lipid‐microinflammation axis in androgenetic alopecia (AGA). Altered sebaceous gland activity, shifts in microbial abundance on the scalp and hair follicle, and follicular microinflammation interact bidirectionally, each reinforcing the others.
Aditya K. Gupta, Elizabeth M. Teasell, Amanda Liddy, Vasiliki Economopoulos   +3 more
wiley   +1 more source

Untargeted Metabolomic and Lipidomic Profiles of Gingival Crevicular Fluid in the Context of Periodontitis

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim(s) This cross‐sectional clinical study aimed to explore the untargeted metabolomic and lipidomic profiles in gingival crevicular fluid (GCF) obtained from healthy individuals and patients with periodontitis. Materials and Methods GCF was collected from 17 periodontally healthy and 19 periodontitis patients.
Caroline H. Henderzahs, Chiaki Yamada, Alexandr Morozov, Thelmalane Yalartai, Vanchit John, Hawra AlQallaf, Alexandru Movila   +6 more
wiley   +1 more source

A Phase I Study of Hydroxychloroquine and Suba-Itraconazole in Men with Biochemical Relapse of Prostate Cancer (HITMAN-PC): Dose Escalation Results. [PDF]

Cancer Res Commun
Talmor B, Marastoni S, Lau B, Yam AO, Yeung N, Lin HM, Li ZJ, Woo H, Pranavan G, Stricker PD, Horvath LG, Koritzinsky M, Wouters BG, Crumbaker M, Joshua AM.   +14 more
europepmc   +1 more source

Multi‐omics profiling of chronic immune‐mediated skin diseases: SKINERGY protocol and strategic evaluation

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The SKINERGY study will investigate six immune‐mediated inflammatory skin diseases through a nationwide collaboration across all Dutch university medical centres. Involving 720 patients and 120 healthy volunteers, it is aimed at generating a high‐quality dataset to identify biomarkers that enable personalized treatment strategies and improved disease ...
N. G. Koster, J. M. P. A. van den Reek, E. M. G. J. de Jong, S. van Beugen, A. I. M. van Laarhoven, I. Haeck, M. de Bruin‐Weller, M. L. Schuttelaar, B. Horvath, A. Gostyński, A. Knulst, M. H. Vermeer, L. Nguyen, L. Gerbens, P. Spuls, M. A. Middelkamp‐Hup, V. Exadaktylos, T. Niemeyer‐van der Kolk, A. R. Schrader, A. M. Sluijmers, J. Versteeg, B. W. M. Arents, I. van Ee, J. L. A. G. van der Zon, M. de Leeuw, T. de Leeuw, P. van den Broek, C. Berkhof, D. Vellinga, S. Weidinger, S. Dubrac, Y. Li, M. van Steensel, M. Marchetti‐Deschmann, M. Maurer, H. van der Zee, J. Damman, D. J. Hijnen, F. Wijk, M. M. B. Seyger, H. Röckmann, D. M. W. Balak, M. B. A. van Doorn, R. Rissmann, The Next Generation ImmunoDermatology (NGID) consortium, Rob Vreeken, Eva Cuypers, Boudewijn Lelieveldt, Abdoel El Ghalbzouri, Hanna Niehues, Ellen van den Bogaard, Tom Ederveen, Els van der Pool, Nanda Olde, Debra Trampe, Ellen Stijl‐’t Hart, Lisanne Wezendonk, Johan Westerhuis, Huma Shehwana, Joerg Schreiber, Jeremy Bost, Mie Bech Lukassen, Jimmy Bakker, Juliette Simons, Fauve van den Berge, Colin Spence, Elise Beljaards, Anastasiia Myronenko, Mariona Oliver   +68 more
wiley   +1 more source

High cholesterol absorption efficiency enhances proatherogenic properties of low‐density lipoprotein particles

Journal of Internal Medicine, EarlyView.
Abstract Background and Aims High cholesterol absorption efficiency is determined by genetic variation in small intestinal sterol transporters and affects one‐third of individuals. Their risk for atherosclerotic cardiovascular disease (ASCVD) is increased compared with low cholesterol absorbers, despite similar serum lipid concentrations.
Katariina Öörni, Lauri Äikäs, Maija Ruuth, Feven Tigistu‐Sahle, Reijo Käkelä, Ingmar Wester, Helena Gylling, Piia Simonen   +7 more
wiley   +1 more source

Adiposome Lipidomic Shifts Following Bariatric Surgery in Association With Weight Loss and Cardiometabolic Benefit.

J Clin Endocrinol Metab
Metwally E, Burton L, Mirza I, Morsy MH, Scichilone G, Mostafa A, Shimotake Y, Lighter M, Bianco FM, Hassan C, Masrur MA, Layden BT, Mahmoud AM.   +12 more
europepmc   +1 more source

Plasma lipidomic profiling reveals the potential protective role of lipids in cerebral small vessel disease. [PDF]

Lipids Health Dis
Wu C, Gao LY, Sun W, Zhao BK, Ma YH, Song HQ, Alzheimer’s Disease Neuroimaging Initiative.   +6 more
europepmc   +1 more source

Kidney triglyceride accumulation in the fasted mouse is dependent upon serum free fatty acids [PDF]

, 2017
Abumrad, Nada A., al, et, Cifarelli, Vincenza   +2 more
core   +2 more sources

Immune endotypes in tuberculosis: Keys to decoding disease complexity

Journal of Internal Medicine, EarlyView.
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor, Julia Guthrie, Lina Davies Forsman, Andrew R. Di Nardo, Susanna Brighenti   +4 more
wiley   +1 more source

Lipidomic and Metagenomic Profiling of Chinese Female Emerging Adults With Oily Scalp. [PDF]

J Cosmet Dermatol
Yang F, Xiang B, Xia D, Wu Y, Chang X, Sun P, Zhang M, Zhang Y.   +7 more
europepmc   +1 more source