Results 211 to 220 of about 41,885 (269)

Global Lipidome Workflow for Mycobacterium tuberculosis Using High‐Resolution Mass Spectrometry

Chemistry–Methods, Volume 6, Issue 4, April 2026.
Pre‐extraction cell homogenisation of Mycobacterium tuberculosis (Mtb) enhances lipid recovery by liquid chromatography‐mass spectrometry. Relative to unhomogenised cells, signals for typically triacylglycerol, cardiolipin and phosphatidylethanolamine increase, broadening lipidome coverage and providing a straightforward means to obtain more ...
Glenda Vasku, Nashied Peton, Evelyn Y.‐W. Huang, Madison R. Nuske, Chai Xin Yu, Xiaoxu Chen, Anna K. Coussens, Ivanhoe K. H. Leung   +7 more
wiley   +1 more source

Brain lipidomics for region-specific biomarker discovery in neurodegenerative diseases. [PDF]

Front Aging Neurosci
Jayaprakash J, Gizaw ST, Gowda D, Hinou H, Nishimura SI, Hui SP, B Gowda SG.   +6 more
europepmc   +1 more source

Optimised Sample Preparation for Metabolic Analysis of Cell Cultures Using DESI‐MS

Chemistry–Methods, Volume 6, Issue 4, April 2026.
Cell pellets are washed once with a 1:1 PBS/AA mixed solution for desalting and pipetted directly onto a reversed‐phase TLC slide as discrete spots and then analysed by desorption electrospray ionisation mass spectrometry imaging (DESI‐MSI). The same slide can be re‐measured for different mass ranges/acquisition modes, enabling comprehensive targeted ...
Wei Chen, Chiara Urban, Hakan Taskiran, Chenyue Dai, Kıvanç Görgülü, Julia Jellusova, Nicole Strittmatter   +6 more
wiley   +1 more source

Multiplexed LC-MS analysis reveals novel insights into grapevine defense mechanisms by expanding metabolome coverage. [PDF]

Metabolomics
Vásquez-Ocmín PG, Pérez A, Romeo-Oliván A, Puech-Pages V, Fournier S, Dumas B, Jacques A, Marti G.   +7 more
europepmc   +1 more source

Targeting Ferroptosis Pathways for Synaptic Protection in Sevoflurane‐Induced Cognitive Impairment: A Nanomedicine Approach

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
Sevoflurane exposure triggers iron‐dependent lipid peroxidation and ferroptosis, leading to synaptic damage and cognitive dysfunction. Targeted nanodelivery systems that cross the blood–brain barrier can precisely modulate ferroptotic pathways, reduce oxidative injury, and rescue synaptic integrity, offering a promising strategy for preventing ...
Bin Zhao, Changming Wang, Mingming Zhang
wiley   +1 more source

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1057-1069, April 2026.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka, Jiri Hricko, Lucie Rudl Kulhava, Michaela Paucova, Michaela Novakova, Veronika Hola, Stanislava Rakusanova, Oliver Fiehn, Vojtech Skop, Ivana Lankova, Iva Miskova, Terezie Pelikanova, Martin Haluzik   +12 more
wiley   +1 more source

Comparative Lipidomic Profiling of Camel and Cow Milk from a Shared Semi-Desert Pasture: Implications for Camel Adaptation to Arid Environments. [PDF]

Molecules
Zhu L, Tan X, Li Z, Gong Q, Duan G, Zang C, Chen Y, Li F.   +7 more
europepmc   +1 more source

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

Drug Testing and Analysis, Volume 18, Issue 4, Page 458-482, April 2026.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source