Results 231 to 240 of about 41,885 (269)

Identification of Blood Pressure‐Associated Metabolites by Integrating Metabolomic and Genetic Analysis

MedComm, Volume 7, Issue 4, April 2026.
This study identified 10 potential causality between metabolites and blood pressure and found potential genetic regulators of two metabolites. Multiomics integration revealed that a genetic variant near the omega‐3 metabolism genes (FADS1/FADS2) may influence blood pressure regulation by modulating prostaglandin E3 levels.
Yuanjiao Liu, Chunxiao Cheng, Xiong‐Fei Pan, Wei Shao, Dan Zhou, Yimin Zhu   +5 more
wiley   +1 more source

Dietary glucuronolactone alleviates hepatic lipid accumulation via the enterohepatic axis in laying hens. [PDF]

J Anim Sci Biotechnol
Shen Y, Chen J, Xiao Y, Shi S.
europepmc   +1 more source

Enhancing Lipidomics With High‐Resolution Ion Mobility‐Mass Spectrometry

PROTEOMICS, Volume 26, Issue 4, Page 7-22, April 2026.
ABSTRACT Lipids, indispensable yet structurally intricate biomolecules, serve as critical regulators of cellular function and disease progression. Conventional lipidomics, constrained by limited resolution for isomeric and low‐abundance species, has been transformed by ion mobility‐mass spectrometry (IM‐MS).
Gaoyuan Lu, Shuling Xu, Penghsuan Huang, Lingjun Li   +3 more
wiley   +1 more source

Lipidomic Profiling of Dechorionated Fertilized Eggs and Egg Chorion in Three Tropical Marine Fish Species: Insights into Reproductive Physiology and Nutrition. [PDF]

Biology (Basel)
Liu YH, Guo HY, Liu BS, Zhu TF, Xian L, Zhang N, Zhu KC, Zhang JS, Zhang DC.   +8 more
europepmc   +1 more source

The crystal structure of human transport and Golgi organization 2 homolog (TANGO2) suggests a cysteine N‐terminal nucleophile (Ntn) hydrolase

Acta Crystallographica Section D, Volume 82, Issue 4, Page 383-396, April 2026.
This study reports the first crystal structure of human TANGO2, mutations of which are responsible for TANGO2 deficiency disorder. The crystallographic analysis demonstrates that interactions between heme and TANGO2 are nonspecific, helping to address ongoing questions about the role of TANGO2 as a heme‐trafficking protein.Recently, there has been ...
Dayong Zhou, Lirong Chen, John Rose, Bi-Cheng Wang   +3 more
wiley   +1 more source

A Cluster of Three snoRNAs Including Jouvence Required in the Gut Determines Lifespan and Confers Neuroprotection Through Metabolic Parameters

Aging Cell, Volume 25, Issue 4, April 2026.
The disruption of a cluster of three snoRNAs in the epithelium of the gut deregulates the lipid and sterol (including the cholesterol) homeostasis. At the whole‐organism level, this chronic deregulation, all along life, decreases lifespan and leads to neurodegenerative lesions in old flies.
Sara Al Issa, Théo Gauvrit, Patricia Daira, Nathalie Bernoud‐Hubac, Jean‐René Martin   +4 more
wiley   +1 more source

In Vitro Modeling of Age‐Associated Lipid Mediator's Impact on Vascular Biology Following Platelet Concentrate Transfusion

Aging Cell, Volume 25, Issue 4, April 2026.
Age‐associated LPA affects adverse reactions and alters platelet and endothelial biology following platelet concentrate transfusion. Age‐associated LPC, S1P could be involved in adverse reactions, in platelet and endothelium biology following a PC transfusion.
Amelie Prier, Mailys Portier, Chloe Heranney, Nancy Kouadio, Charles‐Antoine Arthaud, Marie‐Ange Eyraud, Marco Heestermans, Justine Bertrand‐Michel, Hind Hamzeh‐Cognasse, Fabrice Cognasse, Anne‐Claire Duchez   +10 more
wiley   +1 more source

Integrated lipidomic and transcriptomic analysis of intramuscular fat deposition in yellow-feathered broilers. [PDF]

Poult Sci
Li Z, Malyar RM, Sun H, Ding W, Li Y, Lu L, Shi F.   +6 more
europepmc   +1 more source

Long-chain polyunsaturated fatty acid lipid and oxylipin alterations in postoperative delirium after cardiac surgery. [PDF]

J Lipid Res
Wiredu K, Gowda P, Rhee J, Mueller A, Simon C, Kelly Graves O, Qu JZ, Spite M, McKay TB, Akeju O.   +9 more
europepmc   +1 more source