Results 31 to 40 of about 34,809 (298)

Silencing of enzymes involved in ceramide biosynthesis causes distinct global alterations of lipid homeostasis and gene expression[S]

open access: yesJournal of Lipid Research, 2012
Dysregulation of ceramide synthesis has been associated with metabolic disorders such as atherosclerosis and diabetes. We examined the changes in lipid homeostasis and gene expression in Huh7 hepatocytes when the synthesis of ceramide is perturbed by ...
Wanida Ruangsiriluk   +5 more
doaj   +1 more source

Cellular lipidomics [PDF]

open access: yesThe EMBO Journal, 2005
The cellular lipidome comprises over 1000 different lipids. Most lipids look similar having a polar head and hydrophobic tails. Still, cells recognize lipids with exquisite specificity. The functionality of lipids is determined by their local concentration, which varies between organelles, between the two leaflets of the lipid bilayer and even within ...
openaire   +3 more sources

High-Throughput Screening of Lipidomic Adaptations in Cultured Cells [PDF]

open access: yes, 2019
High-throughput screening of biologically active substances in cell cultures remains challenging despite great progress in contemporary lipidomic techniques.
dB&C FR-RMSC FR   +10 more
core   +3 more sources

Lipidomic analyses, breast- and formula-feeding, and growth in infants. [PDF]

open access: yes, 2014
OBJECTIVE: To evaluate lipidomic differences between breast- and formula-fed infants. STUDY DESIGN: We utilized high-resolution mass-spectrometry methods to analyze 3.2 mm dried blood spot samples collected at ages 3 months (n = 241) and 12 months (n ...
Acerini, Carlo L.   +5 more
core   +3 more sources

Effects of Yeast Product Addition and Fermentation Temperature on Lipid Composition, Taste and Mouthfeel Characteristics of Pinot Noir Wine

open access: yesHorticulturae, 2022
Lipids have important impacts on wine sensory. By targeting the lipid sources in wine, mainly from grape tissues and yeast cell walls, it was possible to alter the wine lipid profile thus potentially changing the final product quality.
Quynh Phan   +3 more
doaj   +1 more source

Profile of Phosphatidylserine Modifications under Nitroxidative Stress Conditions Using a Liquid Chromatography-Mass Spectrometry Based Approach

open access: yesMolecules, 2018
Nitrated lipids have been detected in vitro and in vivo, usually associated with a protective effect. While nitrated fatty acids have been widely studied, few studies reported the nitration and nitroxidation of the phospholipid classes ...
Bruna Neves   +4 more
doaj   +1 more source

Distribution of lipids in the grain of wheat (cv Hereward) determined by lipidomic analysis of milling and pearling fractions [PDF]

open access: yes, 2015
Lipidomic analyses of milling and pearling fractions from wheat grain were carried out to determine differences in composition which could relate to the spatial distribution of lipids in the grain.
Penson, Simon   +21 more
core   +1 more source

Adiponectin Isoforms Differentially Affect Gene Expression and the Lipidome of Primary Human Hepatocytes

open access: yesMetabolites, 2014
Adiponectin (APN) exerts multiple beneficial effects in obesity and protects from liver injury. Different APN isoforms circulate in serum, and here, the effect of low molecular weight (LMW) and higher molecular weight (HMW) APN on primary human ...
Josef Wanninger   +9 more
doaj   +1 more source

Lipidomic, Transcriptomic, and BSA-660K Single Nucleotide Polymorphisms Profiling Reveal Characteristics of the Cuticular Wax in Wheat

open access: yesFrontiers in Plant Science, 2021
Plant epidermal wax helps protect plants from adverse environmental conditions, maintains the function of tissues and organs, and ensures normal plant development.
Jun Zheng   +7 more
doaj   +1 more source

Understanding the Lipidome at the Systems Level with lipidomeR [PDF]

open access: yes, 2020
Abstract Lipidomics is one of the fastest-growing areas of molecular profiling in medicine. While increasing amounts of lipidomics data are generated, tools for analyzing and interpreting these data are not equally widely available. We present the lipidomeR -- a tool specifically designed for systematic interpretation of large lipidome ...
Suvitaival, Tommi   +1 more
openaire   +1 more source

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