Results 31 to 40 of about 42,427 (286)
Journal of Lipid Research, 2012 Dysregulation of ceramide synthesis has been associated with metabolic disorders such as atherosclerosis and diabetes. We examined the changes in lipid homeostasis and gene expression in Huh7 hepatocytes when the synthesis of ceramide is perturbed by ...
Wanida Ruangsiriluk +5 more
doaj +1 more source
Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression [PDF]
, 2018 The complete mechanism accounting for the progression from simple steatosis to steatohepatitis in nonalcoholic fatty liver disease (NAFLD) has not been elucidated.
Avolio, Carlo +11 more
core +2 more sources
Metabolic Modulation Predicts Heart Failure Tests Performance [PDF]
, 2019 The metabolic changes that accompany changes in Cardiopulmonary testing (CPET) and heart failure biomarkers (HFbio) are not well known. We undertook metabolomic and lipidomic phenotyping of a cohort of heart failure (HF) patients and utilized Multiple ...
Abbate, Antonio +11 more
core +3 more sources
Microbiology Spectrum, 2014 ABSTRACTLipidomics is a distinct subspecialty of metabolomics concerned with hydrophobic molecules that organize into membranes. Most of the lipid classes present inMycobacterium tuberculosisare found only inActinobacteriaand show extreme structural diversity. This article highlights the conceptual basis and the practical challenges associated with the
Layre, Emilie +3 more
openaire +2 more sources
Applying metabolomics to cardiometabolic intervention studies and trials: past experiences and a roadmap for the future [PDF]
, 2016 Metabolomics and lipidomics are emerging methods for detailed phenotyping of small molecules in samples. It is hoped that such data will: (i) enhance baseline prediction of patient response to pharmacotherapies (beneficial or adverse); (ii) reveal ...
Preiss, David +3 more
core +2 more sources
Lipid droplets and lipotoxicity during autophagy. [PDF]
, 2017 Lipid droplets (LDs) are neutral lipid storage organelles that provide a rapidly accessible source of fatty acids (FAs) for energy during periods of nutrient deprivation.
Nguyen, Truc, Olzmann, James
core +2 more sources
Horticulturae, 2022 Lipids have important impacts on wine sensory. By targeting the lipid sources in wine, mainly from grape tissues and yeast cell walls, it was possible to alter the wine lipid profile thus potentially changing the final product quality.
Quynh Phan +3 more
doaj +1 more source
Immunometabolism is a key factor for the persistent spontaneous elite control of HIV-1 infection [PDF]
, 2019 Approximately 25% of elite controllers (ECs) lose their virological control by mechanisms that are only partially known. Recently, immunovirological and proteomic factors have been associated to the loss of spontaneous control. Our aim was to perform a
Alba, Verónica +12 more
core +2 more sources
Molecules, 2018 Nitrated lipids have been detected in vitro and in vivo, usually associated with a protective effect. While nitrated fatty acids have been widely studied, few studies reported the nitration and nitroxidation of the phospholipid classes ...
Bruna Neves +4 more
doaj +1 more source
Development of an R script for simple lipidomic and metabolomic data analysis [PDF]
, 2020 Background: Metabolomic and lipidomic studies generate vast quantities of data that are often analysed in a closed software environment with little to no access to the underlying algorithms.
Alshammari, Suad +4 more
core +1 more source