Results 41 to 50 of about 42,427 (286)

The role of human cytochrome P450 2E1 in liver inflammation and fibrosis. [PDF]

, 2017
Cytochrome P450 2E1 (CYP2E1) plays an important role in alcohol and toxin metabolism by catalyzing the conversion of substrates into more polar metabolites and producing reactive oxygen species.
Brenner, David A, Davidson, Nicholas O, Dennis, Edward A, Hu, Ronglin, Karin, Gabriel, Kisseleva, Tatiana, Koyama, Yukinori, Liang, Shuang, Ma, Hsiao-Yen, Quehenberger, Oswald, Sun, Mengxi, Xu, Jun   +11 more
core   +1 more source

Adiponectin Isoforms Differentially Affect Gene Expression and the Lipidome of Primary Human Hepatocytes

Metabolites, 2014
Adiponectin (APN) exerts multiple beneficial effects in obesity and protects from liver injury. Different APN isoforms circulate in serum, and here, the effect of low molecular weight (LMW) and higher molecular weight (HMW) APN on primary human ...
Josef Wanninger, Gerhard Liebisch, Kristina Eisinger, Markus Neumeier, Charalampos Aslanidis, Lisa Voggenreiter, Rebekka Pohl, Thomas S. Weiss, Sabrina Krautbauer, Christa Buechler   +9 more
doaj   +1 more source

Lipidomic, Transcriptomic, and BSA-660K Single Nucleotide Polymorphisms Profiling Reveal Characteristics of the Cuticular Wax in Wheat

Frontiers in Plant Science, 2021
Plant epidermal wax helps protect plants from adverse environmental conditions, maintains the function of tissues and organs, and ensures normal plant development.
Jun Zheng, Jun Zheng, Chenkang Yang, Xingwei Zheng, Suxian Yan, Fei Qu, Jiajia Zhao, Yanxi Pei   +7 more
doaj   +1 more source

A Metabolomic Profiling of Intra-Uterine Growth Restriction in Placenta and Cord Blood Points to an Impairment of Lipid and Energetic Metabolism

Biomedicines, 2022
(1) Background: Intrauterine growth restriction (IUGR) involves metabolic changes that may be responsible for an increased risk of metabolic and cardiovascular diseases in adulthood.
Juan Manuel Chao de la Barca, Floris Chabrun, Tiphaine Lefebvre, Ombeline Roche, Noémie Huetz, Odile Blanchet, Guillaume Legendre, Gilles Simard, Pascal Reynier, Géraldine Gascoin   +9 more
doaj   +1 more source

Open field study of some Zea mays hybrids, lipid compounds and fumonisins accumulation [PDF]

, 2015
Lipid molecules are increasingly recognized as signals exchanged by organisms interacting in pathogenic and/or symbiotic ways. Some classes of lipids actively determine the fate of the interactions.
Battilani, Paola, Cirlini, Martin, Dall’Asta, Chiara, Fanelli, Corrado, Galaverna, Gianni, Giorni, Paola, Ludovici, Matteo, Reverberi, Massimo, Scala, Valeria   +8 more
core   +2 more sources

Cyclocarya paliurus Leaves Tea Improves Dyslipidemia in Diabetic Mice: A Lipidomics-Based Network Pharmacology Study

Frontiers in Pharmacology, 2018
Hyperlipidemia and hepatic steatosis afflict over 75% of patients with type 2 diabetes, causing diabetic dyslipidemia. Cyclocarya paliurus (CP) leaf is a herbal tea which has long been consumed by the Chinese population, particularly people suffering ...
Lixiang Zhai, Zi-wan Ning, Tao Huang, Bo Wen, Bo Wen, Cheng-hui Liao, Cheng-yuan Lin, Ling Zhao, Hai-tao Xiao, Zhao-xiang Bian, Zhao-xiang Bian   +10 more
doaj   +1 more source

The patatin-like phospholipase PfPNPLA2 is involved in the mitochondrial degradation of phosphatidylglycerol during Plasmodium falciparum blood stage development

Frontiers in Cellular and Infection Microbiology, 2023
Plasmodium falciparum is an Apicomplexa responsible for human malaria, a major disease causing more than ½ million deaths every year, against which there is no fully efficient vaccine.
Serena Shunmugam, Nyamekye Quansah, Ansgar Flammersfeld, Md Muzahidul Islam, Juliane Sassmannshausen, Sandra Bennink, Yoshiki Yamaryo-Botté, Gabriele Pradel, Cyrille Y. Botté   +8 more
doaj   +1 more source

Aerobic growth of Rhodococcus aetherivorans BCP1 using selected naphthenic acids as the sole carbon and energy sources [PDF]

, 2018
Naphthenic acids (NAs) are an important group of toxic organic compounds naturally occurring in hydrocarbon deposits. This work shows that Rhodococcus aetherivorans BCP1 cells not only utilize a mixture of eight different NAs (8XNAs) for growth but they ...
Cappelletti M., Crognale S., Demeter M. A., Fedi S., Ferreri C., Milazzo G., Petruccioli M., Piacenza E., Presentato A., Sansone A., Steinbuchel A., Turner R. J., Zannoni D.   +12 more
core   +2 more sources

Influence of the sebaceous gland density on the stratum corneum lipidome [PDF]

, 2018
The skin surface lipids (SSL) result from the blending of sebaceous and epidermal lipids, which derive from the sebaceous gland (SG) secretion and the permeability barrier of the stratum corneum (SC), respectively.
Camera, Emanuela, Kozul, Nina, Ludovici, Matteo, Materazzi, Stefano, Picardo, Mauro, Risoluti, Roberta   +5 more
core   +1 more source

Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages. [PDF]

, 2018
Activation of liver X receptors (LXRs) with synthetic agonists promotes reverse cholesterol transport and protects against atherosclerosis in mouse models.
Bahadorani, John, Edillor, Chantle R, Glass, Christopher K, Grossman, Tamar R, Henke, Adam, McDonald, Jeffrey G, Muse, Evan D, Ozeki, Katherine A, Roland, Jason T, Seidman, Jason S, Spann, Nathanael J, Tao, Jenhan, Thompson, Bonne M, Tremblay, Matthew S, Troutman, Ty D, Tsimikas, Sotirios, Yu, Shan   +16 more
core   +1 more source