Results 21 to 30 of about 23,923 (256)
Molecules, 2023 Nobiletin (NOB) is a naturally occurring compound, commonly found in citrus peel, that shows hepatoprotective and lipid-reducing effects. However, the lipid biomarkers and the potential improvement mechanisms have not been adequately explored. Therefore,
Zunli Ke +6 more
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Frontiers in Immunology, 2022 Systemic lupus erythematosus (SLE) is a complex autoimmune disease with heterogeneous clinical manifestations and the pathogenesis of SLE is still unclear.
Xiaolan Huang +17 more
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Myocardial Lipidomics. Developments in myocardial nuclear lipidomics [PDF]
Frontiers in Bioscience, 2007 The development of electrospray ionization mass spectrometry has been critical for the analyses of lipidomes from subcellular organelles. The myocardial nuclear lipidome likely has a key role in the molecular regulation of gene expression. In fact, recent studies have suggested that specific phospholipid classes bind and regulate specific transcription
Carolyn J, Albert +4 more
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Frontiers in Cellular and Infection Microbiology, 2020 Malassezia yeasts are lipid dependent and part of the human and animal skin microbiome. However, they are also associated with a variety of dermatological conditions and even cause systemic infections.
Adriana Marcela Celis Ramírez +13 more
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Lipidomics unveils the complexity of the lipidome in metabolic diseases [PDF]
Clinical and Translational Medicine, 2018 AbstractDysregulation of lipid metabolism is responsible for pathologies of human diseases including metabolic diseases. Recent advances in lipidomics analysis allow for the targeted and untargeted identification of lipid species and for their quantification in normal and diseased conditions.
Todd A. Lydic, Young‐Hwa Goo
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Frontiers in Bioengineering and Biotechnology, 2018 Macroalgae are a natural source of clinically relevant molecules such as polyunsaturated and monounsaturated fatty acids. The Antarctic environment, due to its cold climate, leads to high production of these bioactive molecules.
Bruna Silveira Pacheco +12 more
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The EMBO Journal, 2005 The cellular lipidome comprises over 1000 different lipids. Most lipids look similar having a polar head and hydrophobic tails. Still, cells recognize lipids with exquisite specificity. The functionality of lipids is determined by their local concentration, which varies between organelles, between the two leaflets of the lipid bilayer and even within ...
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Journal of Lipid Research, 2012 Dysregulation of ceramide synthesis has been associated with metabolic disorders such as atherosclerosis and diabetes. We examined the changes in lipid homeostasis and gene expression in Huh7 hepatocytes when the synthesis of ceramide is perturbed by ...
Wanida Ruangsiriluk +5 more
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Microbiology Spectrum, 2014 ABSTRACTLipidomics is a distinct subspecialty of metabolomics concerned with hydrophobic molecules that organize into membranes. Most of the lipid classes present inMycobacterium tuberculosisare found only inActinobacteriaand show extreme structural diversity. This article highlights the conceptual basis and the practical challenges associated with the
Layre, Emilie +3 more
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The Lipidome Fingerprint of Longevity [PDF]
Molecules, 2020 Lipids were determinants in the appearance and evolution of life. Recent studies disclose the existence of a link between lipids and animal longevity. Findings from both comparative studies and genetics and nutritional interventions in invertebrates, vertebrates, and exceptionally long-lived animal species—humans included—demonstrate that both the cell
Mariona Jové +7 more
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