Results 131 to 140 of about 65,728 (277)
Biomarkers and subtypes of deranged lipid metabolism in non-alcoholic fatty liver disease. [PDF]
Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous and complex disease that is imprecisely diagnosed by liver biopsy. NAFLD covers a spectrum that ranges from simple steatosis, nonalcoholic steatohepatitis (NASH) with varying degrees of fibrosis,
Alonso, Cristina+3 more
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Ribosomes are regulated by evolutionarily conserved ubiquitination/deubiquitination events. We uncover the role of the deubiquitinase OTUD6 in regulating global protein translation through deubiquitination of the RPS7/eS7 subunit on the free 40 S ...
Sammy Villa+8 more
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Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: a bridge to lipidomics [PDF]
Xianlin Han, Richard W. Gross
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On the future of “omics”: lipidomics
AbstractSummaryFollowing in the wake of the genomic and proteomic revolutions new fields of “omics” research are emerging. The metabolome provides the natural complement to the genome and proteome, however, the extreme physicochemical diversity of the metabolome leads to a subdivision of metabolites into compounds soluble in aqueous solutions or those ...
Yuqin Wang+3 more
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Application of Lipidomics in the Researches of Food Quality
Lipidomics, as a metabolomics approach centered on lipids, aims to comprehensively analyze lipids within biological systems. In recent years, mass spectrometry (MS)-based lipidomics analysis techniques have been widely utilized to address qualitative and
Haolei HAN+5 more
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Characterization and direct quantitation of cerebroside molecular species from lipid extracts by shotgun lipidomics [PDF]
Xianlin Han, Hua Cheng
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Colorectal cancer (CRC) is the second leading cause of cancer-related deaths. Understanding its pathophysiology is essential for developing efficient strategies to treat this disease. Lipidome, the sum of total lipids, related enzymes, receptors and signaling pathways, plays crucial roles in multiple cellular processes, such as metabolism, energy ...
Yongsheng Li+4 more
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Identification of a Widespread Palmitoylethanolamide Contamination in Standard Laboratory Glassware. [PDF]
Introduction: Fatty acid ethanolamides (FAEs) are a family of lipid mediators that participate in a host of biological functions. Procedures for the quantitative analysis of FAEs include organic solvent extraction from biological matrices (e.g., blood ...
Angelini, Roberto+3 more
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