Results 131 to 140 of about 65,728 (277)

Biomarkers and subtypes of deranged lipid metabolism in non-alcoholic fatty liver disease. [PDF]

open access: yes, 2019
Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous and complex disease that is imprecisely diagnosed by liver biopsy. NAFLD covers a spectrum that ranges from simple steatosis, nonalcoholic steatohepatitis (NASH) with varying degrees of fibrosis,
Alonso, Cristina   +3 more
core  

OTUD6 deubiquitination of RPS7/eS7 on the free 40 S ribosome regulates global protein translation and stress

open access: yesNature Communications
Ribosomes are regulated by evolutionarily conserved ubiquitination/deubiquitination events. We uncover the role of the deubiquitinase OTUD6 in regulating global protein translation through deubiquitination of the RPS7/eS7 subunit on the free 40 S ...
Sammy Villa   +8 more
doaj   +1 more source

On the future of “omics”: lipidomics

open access: yesJournal of Inherited Metabolic Disease, 2011
AbstractSummaryFollowing in the wake of the genomic and proteomic revolutions new fields of “omics” research are emerging. The metabolome provides the natural complement to the genome and proteome, however, the extreme physicochemical diversity of the metabolome leads to a subdivision of metabolites into compounds soluble in aqueous solutions or those ...
Yuqin Wang   +3 more
openaire   +5 more sources

Application of Lipidomics in the Researches of Food Quality

open access: yesShipin gongye ke-ji
Lipidomics, as a metabolomics approach centered on lipids, aims to comprehensively analyze lipids within biological systems. In recent years, mass spectrometry (MS)-based lipidomics analysis techniques have been widely utilized to address qualitative and
Haolei HAN   +5 more
doaj   +1 more source

Lipidome in colorectal cancer

open access: yesOncotarget, 2016
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths. Understanding its pathophysiology is essential for developing efficient strategies to treat this disease. Lipidome, the sum of total lipids, related enzymes, receptors and signaling pathways, plays crucial roles in multiple cellular processes, such as metabolism, energy ...
Yongsheng Li   +4 more
openaire   +5 more sources

Identification of a Widespread Palmitoylethanolamide Contamination in Standard Laboratory Glassware. [PDF]

open access: yes, 2017
Introduction: Fatty acid ethanolamides (FAEs) are a family of lipid mediators that participate in a host of biological functions. Procedures for the quantitative analysis of FAEs include organic solvent extraction from biological matrices (e.g., blood ...
Angelini, Roberto   +3 more
core  

Lipidomics [PDF]

open access: yesAnalytical Chemistry, 2014
Richard W, Gross, Michal, Holčapek
openaire   +2 more sources

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