Results 11 to 20 of about 661,416 (267)

Efficient One-Pot Synthesis of Novel Caffeic Acid Derivatives as Potential Antimalarials

open access: yesJournal of Parasitology Research, 2023
New protocol for the preparation of the novel caffeic acid derivatives using the Wittig reaction has been applied to follow the principles of green chemistry.
Katarzyna Sidoryk   +8 more
doaj   +1 more source

PTH induces bone loss via microbial-dependent expansion of intestinal TNF+ T cells and Th17 cells

open access: yesNature Communications, 2020
T cells are involved in the bone loss induced by parathyroid hormone (PTH), but their origin is unknown. Here, the authors show that the intestinal microbiota is required for PTH to induce bone loss and describes mechanisms for microbiota-mediated gut ...
Mingcan Yu   +7 more
doaj   +1 more source

Metabolomics analysis of type 2 diabetes remission identifies 12 metabolites with predictive capacity: a CORDIOPREV clinical trial study

open access: yesBMC Medicine, 2022
Background Type 2 diabetes mellitus (T2DM) is one of the most widely spread diseases, affecting around 90% of the patients with diabetes. Metabolomics has proven useful in diabetes research discovering new biomarkers to assist in therapeutical studies ...
Marina Mora-Ortiz   +12 more
doaj   +1 more source

Cholesterol oxidized products in foods: potential health hazards and the role of antioxidants in prevention

open access: yesGrasas y Aceites, 2004
Cholesterol is a molecule with a double bond in its structure, and therefore it is susceptible to oxidation leading to the formation of oxysterols. These oxidation products are found in many commonly consumed foods and are formed during their manufacture
Alfonso Valenzuela   +2 more
doaj   +1 more source

Role of Snf-β in lipid accumulation in the high lipid‐producing fungus Mucor circinelloides WJ11

open access: yesMicrobial Cell Factories, 2021
Background Mucor circinelloides WJ11 is a high-lipid producing strain and an excellent producer of γ-linolenic acid (GLA) which is crucial for human health.
Shaista Nosheen   +10 more
doaj   +1 more source

Carboxylesterases in lipid metabolism: from mouse to human

open access: yesProtein & Cell, 2017
Mammalian carboxylesterases hydrolyze a wide range of xenobiotic and endogenous compounds, including lipid esters. Physiological functions of carboxylesterases in lipid metabolism and energy homeostasis in vivo have been demonstrated by genetic ...
Jihong Lian   +2 more
doaj   +1 more source

HDL cholesterol efflux normalised to apoA-I is associated with future development of type 2 diabetes: from the CORDIOPREV trial

open access: yesScientific Reports, 2017
This prospective study evaluated whether baseline cholesterol efflux is associated with future development of type 2 diabetes (T2DM) in cardiovascular patients.
Ruth Blanco-Rojo   +11 more
doaj   +1 more source

Lipids and lipid metabolism in the eye [PDF]

open access: yesJournal of Lipid Research, 2009
The vertebrate eye is a complex sensory organ consisting of multiple, distinct tissues, each having its own unique biochemical composition, structure, and physiological function. Key among these are the retina, lens, and cornea, working in concert to bring photons of light into the eye, focus them correctly on the retina, and convert their energy into ...
openaire   +4 more sources

Paraoxonase1-192 polymorphism modulates the effects of regular and acute exercise on paraoxonase1 activity

open access: yesJournal of Lipid Research, 2002
Regular exercise practise is a protective factor against coronary heart disease and enhances antioxidant systems, whereas acute exercise appears to be a major source of increased oxidative stress.
Marta Tomás   +8 more
doaj   +1 more source

Mucor circinelloides: a model organism for oleaginous fungi and its potential applications in bioactive lipid production

open access: yesMicrobial Cell Factories, 2022
Microbial oils have gained massive attention because of their significant role in industrial applications. Currently plants and animals are the chief sources of medically and nutritionally important fatty acids. However, the ever-increasing global demand
Abu Bakr Ahmad Fazili   +8 more
doaj   +1 more source

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