Results 21 to 30 of about 1,965,967 (342)
Update of the CHARMM all-atom additive force field for lipids: validation on six lipid types.
Journal of Physical Chemistry B, 2010 A significant modification to the additive all-atom CHARMM lipid force field (FF) is developed and applied to phospholipid bilayers with both choline and ethanolamine containing head groups and with both saturated and unsaturated aliphatic chains ...
Jeffery B. Klauda +8 more
semanticscholar +1 more source
Lipid and Lipidation in Membrane Fusion
The Journal of Membrane Biology, 2022 Membrane fusion plays a lead role in the transport of vesicles, neurotransmission, mitochondrial dynamics, and viral infection. There are fusion proteins that catalyze and regulate the fusion. Interestingly, various types of fusion proteins are present in nature and they possess diverse mechanisms of action.
Avijit Sardar +4 more
openaire +2 more sources
BMC Medicine, 2022 Background Type 2 diabetes mellitus (T2DM) is one of the most widely spread diseases, affecting around 90% of the patients with diabetes. Metabolomics has proven useful in diabetes research discovering new biomarkers to assist in therapeutical studies ...
Marina Mora-Ortiz +12 more
doaj +1 more source
Obesity, Bioactive Lipids, and Adipose Tissue Inflammation in Insulin Resistance
Nutrients, 2020 Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes. The exact mechanism by which adipose tissue induces insulin resistance is still unclear.
Iwona Kojta +2 more
semanticscholar +1 more source
Role of Snf-β in lipid accumulation in the high lipid‐producing fungus Mucor circinelloides WJ11
Microbial Cell Factories, 2021 Background Mucor circinelloides WJ11 is a high-lipid producing strain and an excellent producer of γ-linolenic acid (GLA) which is crucial for human health.
Shaista Nosheen +10 more
doaj +1 more source
Grasas y Aceites, 2004 Cholesterol is a molecule with a double bond in its structure, and therefore it is susceptible to oxidation leading to the formation of oxysterols. These oxidation products are found in many commonly consumed foods and are formed during their manufacture
Alfonso Valenzuela +2 more
doaj +1 more source
PTH induces bone loss via microbial-dependent expansion of intestinal TNF+ T cells and Th17 cells
Nature Communications, 2020 T cells are involved in the bone loss induced by parathyroid hormone (PTH), but their origin is unknown. Here, the authors show that the intestinal microbiota is required for PTH to induce bone loss and describes mechanisms for microbiota-mediated gut ...
Mingcan Yu +7 more
doaj +1 more source
Efficient One-Pot Synthesis of Novel Caffeic Acid Derivatives as Potential Antimalarials
Journal of Parasitology Research, 2023 New protocol for the preparation of the novel caffeic acid derivatives using the Wittig reaction has been applied to follow the principles of green chemistry.
Katarzyna Sidoryk +8 more
doaj +1 more source
Lipids and lipid metabolism in the eye [PDF]
Journal of Lipid Research, 2009 The vertebrate eye is a complex sensory organ consisting of multiple, distinct tissues, each having its own unique biochemical composition, structure, and physiological function. Key among these are the retina, lens, and cornea, working in concert to bring photons of light into the eye, focus them correctly on the retina, and convert their energy into ...
openaire +6 more sources
Carboxylesterases in lipid metabolism: from mouse to human
Protein & Cell, 2017 Mammalian carboxylesterases hydrolyze a wide range of xenobiotic and endogenous compounds, including lipid esters. Physiological functions of carboxylesterases in lipid metabolism and energy homeostasis in vivo have been demonstrated by genetic ...
Jihong Lian +2 more
doaj +1 more source