Results 71 to 80 of about 1,447,518 (357)

Fatty acid composition and technological quality of the lipids produced by the microalga Scenedesmus dimorphus 1237 as a function of culturing conditions [PDF]

, 2016
Scendesmus dimorphus is an oleaginous eukaryotic microalga, able to produce and accumulate lipids up to a weight fraction of 49%. Aim of the present work is investigating the production of lipids by S.
Bravi, Marco, Cicci, Agnese
core   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee, Graeme S. V. McDowell, Darryl C. De Vivo, Daniel Friedman, Samuel F. Berkovic, Maria Spanou, Argirios Dinopoulos, Katheryn Grand, Pedro A. Sanchez‐Lara, Michelle Allen‐Sharpley, Jodi Warman‐Chardon, Alexander Solyom, Thierry Levade, Edward H. Schuchman, Steffany A. L. Bennett, David A. Dyment, Toni S. Pearson   +16 more
wiley   +1 more source

Dependence on dietary cholesterol for n-3 polyunsaturated fatty acid-induced changes in plasma cholesterol in the Syrian hamster.

Journal of Lipid Research, 1992
Male Syrian hamsters consumed diets containing incremental increases in dietary n-3 fatty acids from fish oil with either low (0.015% w/w) or moderate (0.1% w/w) dietary cholesterol content.
ME Surette, J Whelan, GP Lu, KS Broughton, JE Kinsella   +4 more
doaj  

Effect of long-term Mediterranean versus low-fat diet on neutrophil count, and type 2 diabetes mellitus remission in patients with coronary heart disease: results from the CORDIOPREV study

Nutrition & Diabetes
Background Recent evidence links diet and physical activity with type 2 diabetes mellitus (T2DM) remission, but emerging findings suggest that immune system dysregulation may play a crucial role.
Hatim Boughanem, Francisco M. Gutierrez-Mariscal, Antonio Pablo Arenas-de Larriva, José D. Torres-Peña, Juan L. Romero-Cabrera, Oriol Alberto Rangel-Zuñiga, Helena García-Fernández, Alicia Podadera-Herreros, Fernando Rodríguez-Cantalejo, Oliver Soehnlein, Manuel Macias-Gonzalez, Francisco J. Tinahones, Elena M. Yubero Serrano, Pablo Perez-Martinez, Javier Delgado-Lista, José López-Miranda   +15 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Sex-specific differences in intestinal microbiota associated with cardiovascular diseases

Biology of Sex Differences
Background Cardiovascular diseases (CVD), including coronary heart disease (CHD), display a higher prevalence in men than women. This study aims to evaluate the variations in the intestinal microbiota between men and women afflicted with CHD and ...
Helena Garcia-Fernandez, Antonio P. Arenas-de Larriva, Javier Lopez-Moreno, Francisco M. Gutierrez-Mariscal, Juan L. Romero-Cabrera, Helena Molina-Abril, Jose D. Torres-Peña, Diego Rodriguez-Cano, Maria M. Malagon, Jose M. Ordovas, Javier Delgado-Lista, Pablo Perez-Martinez, Jose Lopez-Miranda, Antonio Camargo   +13 more
doaj   +1 more source

13C metabolic flux analysis on roles of malate transporter in lipid accumulation of Mucor circinelloides

Microbial Cell Factories, 2019
Background Mitochondrial and cytoplasmic malate transporter proteins are responsible for transmembrane transport of malate, thereby linking malate metabolism in various subcellular regions of the cell.
Lu Wang, Huaiyuan Zhang, Yao Zhang, Yuanda Song   +3 more
doaj   +1 more source

1-h Glucose During Oral Glucose Tolerance Test Predicts Hyperglycemia Relapse-Free Survival in Obese Black Patients With Hyperglycemic Crises

Frontiers in Endocrinology, 2022
ObjectiveApproximately 50% of obese Black patients with unprovoked diabetic ketoacidosis (DKA) or severe hyperglycemia (SH) at new-onset diabetes achieve near-normoglycemia remission with intensive insulin treatment.
Ram Jagannathan, Darko Stefanovski, Dawn D. Smiley, Omolade Oladejo, Lucia F. Cotten, Guillermo Umpierrez, Priyathama Vellanki   +6 more
doaj   +1 more source