Results 101 to 110 of about 8,324 (204)

Cell envelope polysaccharide modifications alter the surface properties and interactions of Mycobacterium abscessus with innate immune cells in a morphotype-dependent manner

mBio
Mycobacterium abscessus is one of the leading causes of pulmonary infections caused by non-tuberculous mycobacteria. The ability of M. abscessus to establish a chronic infection in the lung relies on a series of adaptive mutations impacting, in part ...
Elena Lian, Juan M. Belardinelli, Kavita De, Arun Prasad Pandurangan, Shiva K. Angala, Zuzana Palčeková, Anna E. Grzegorzewicz, Josephine M. Bryant, Tom L. Blundell, Julian Parkhill, R. Andres Floto, William H. Wheat, Mary Jackson   +12 more
doaj   +1 more source

A Small Multidrug Resistance-like Transporter Involved in the Arabinosylation of Arabinogalactan and Lipoarabinomannan in Mycobacteria*

, 2012
International audienceBackground: (Glyco)lipid translocation across the plasma membrane plays a pivotal role in the biogenesis of the mycobacterial cell envelope.
Noguera, Audrey, Nigou, Jérôme, Angala, Shiva Kumar, Gilleron, Martine, Dhouib, Rabeb, Korduláková, Jana, Larrouy-Maumus, Gerald, Mikušová, Katarína, Pham, Ha, Valentínová, Lucia, Puzo, Germain, Zuberogoitia, Sophie, Brennan, Patrick.J., Villela, Anne Drumond, Škovierová, Henrieta, Jackson, Mary   +15 more
core   +1 more source

A new strategy improving TB diagnosis: stratified urine LAM test based on lymphocyte counts

Frontiers in Cellular and Infection Microbiology
BackgroundTraditional lipoarabinomannan tests have limited sensitivity in HIV-negative individuals. Our aims were to compare chemiluminescence-based LAM (AIMLAM) and other diagnostic modalities in HIV-negative patients and to explore whether lymphocyte ...
Hongzhi Li, Hongzhi Li, Hongzhi Li, Xian Gao, Xian Gao, Xian Gao, Dandan Liu, Dandan Liu, Dandan Liu, Zhe Li, Zhe Li, Zhe Li, Jing Li, Jing Li, Jing Li   +14 more
doaj   +1 more source

Tuberculosis in antiretroviral treatment services in resource-limited settings: addressing the challenges of screening and diagnosis. [PDF]

, 2011
The high burden of tuberculosis (TB) among patients accessing antiretroviral treatment (ART) services in resource-limited settings is a major cause of morbidity and mortality and is associated with nosocomial transmission risk.
Lawn, Stephen D, Robin Wood, Wood, Robin, Stephen D. Lawn   +3 more
core   +1 more source

Editorial: Mycobacterial Glycolipids—Role in Immunomodulation and Targets for Vaccine Development

Frontiers in Immunology, 2020
Gunilla Källenius, Jérôme Nigou, Andrea Cooper, Margarida Correia-Neves, Margarida Correia-Neves, Margarida Correia-Neves   +5 more
doaj   +1 more source

NILAI DIAGNOSTIK RAPID ANTIGEN LIPOARABINOMANNAN URINE UNTUK MENDIAGNOSIS TUBERKULOSIS PARU AKTIF PADA PASIEN HIV [PDF]

Pendahuluan: Diagnosis tuberkulosis (TB) pada pasien HIV-positif masih sulit karena rendahnya hasil diagnostik tes berbasis sputum konvensional dan presentasi klinis yang atipikal. Tes lipoarabinomannan (LAM) urine menawarkan alternatif diagnostik yang
REVAN, ALIANTINO
core  

The First Total Synthesis of a Highly Branched Arabinofuranosyl Hexasaccharide Found at the Nonreducing Termini of Mycobacterial Arabinogalactan and Lipoarabinomannan

, 2016
The first total synthesis of the arabinofuranosyl hexasaccharide present at the nonreducing termini of mycobacterial arabinogalactan and lipoarabinomannan is reported.
Francis W. D'Souz (3029523), Todd L. Lowary (332228)   +1 more
core   +1 more source

Lipoarabinomannan-Responsive Polycytotoxic T Cells Are Associated with Protection in Human Tuberculosis

, 2016
RationaleThe development of host-targeted, prophylactic, and therapeutic interventions against tuberculosis requires a better understanding of the immune mechanisms that determine the outcome of infection with Mycobacterium tuberculosis.ObjectivesTo ...
Busch, Martin, Stenger, Steffen, Herzmann, Christian, Bloom, Barry R, Mayer, Daniel, Lange, Christoph, Höfer, Christoph, Muche, Rainer, Kallert, Stephanie, Zimmermann, Andreas, Modlin, Robert L, Zenk, Sebastian F   +11 more
core   +1 more source

Diagnostic Efficiency of the Blood-Based Cepheid 3-Gene Host Response Test and Urine-Based Lipoarabinomannan for Active Tuberculosis Case Detection at a General Hospital in China

Infection and Drug Resistance
Zhongkang Ji,1,* Sheng Bi,1,* Bin Lu,1,2 Lin Zheng,1 Xiuyuan Jin,1 Shujuan Huang,1 Liangxiu Jiang,1 Yuping Wang,1 Cheng Ding,1 Kaijin Xu1 1State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center ...
Ji Z, Bi S, Lu B, Zheng L, Jin X, Huang S, Jiang L, Wang Y, Ding C, Xu K   +9 more
doaj  

Identification of a novel mannose-capped lipoarabinomannan in Amycolatopsos sulphurea

, 2003
The genus Amycolatopsis is a member of the phylogenetic group nocardioform actinomycetes, which also includes the genus Mycobacterium. Members of this group have a characteristic cell envelope structure, dominated by various complex lipids and ...
Gibson, Kevin, Puzo, Germain, Constant, P, Besra, Gurdyal; id_orcid, Nigou, Jérôme, Constant, Patricia, Besra, Gurdyal, Puzo, G, Nigou, J, Gilleron, Martine, Gilleron, M   +10 more
core   +1 more source