Results 21 to 30 of about 11,446 (217)

Diagnostic and prognostic performance of urinary neutrophil gelatinase‐associated lipocalin in patients with cirrhosis and acute kidney injury

open access: yesHepatology, EarlyView., 2022
Diagnostic and prognostic ability of urinary NGAL in patients with cirrhosis and AKI. Abstract Background and Aims Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI.
Carmine Gambino   +14 more
wiley   +1 more source

Ex vivo and in vivo regulation of lipocalin-2, a novel adipokine, by insulin [PDF]

open access: yes, 2009
OBJECTIVE - Lipocalin-2, a novel adipokine, has been shown to be elevated in obese, insulin-resistant, and diabetic Subjects. We therefore sought to study the ex vivo and in vivo effects of insulin on lipocalin-2 levels in humans. RESEARCH DESIGN AND
Randeva, Harpal S.   +6 more
core   +1 more source

Immune responses to inhalant mammalian allergens

open access: yesFrontiers in Immunology, 2014
In Europe and the USA at least one person in four is exposed every day to inhalant allergens of mammalian origin, a considerable number is regularly exposed for professional reasons and almost everyone is occasionally exposed to inhalant allergens from ...
François eHentges   +3 more
doaj   +1 more source

Dimerization of lipocalin allergens [PDF]

open access: yesScientific Reports, 2015
AbstractLipocalins are one of the most important groups of inhalant animal allergens. The analysis of structural features of these proteins is important to get insights into their allergenicity. We have determined two different dimeric crystal structures for bovine dander lipocalin Bos d 2, which was earlier described as a monomeric allergen.
Miettinen Ilja   +5 more
openaire   +3 more sources

Neutrophil gelatinase-associated lipocalin: its response to hypoxia and association with acute mountain sickness. [PDF]

open access: yes, 2013
Acute Mountain Sickness (AMS) is a common clinical challenge at high altitude (HA). A point-of-care biochemical marker for AMS could have widespread utility.
O'Hara, J   +11 more
core   +1 more source

β-Lactoglobulin and Glycodelin: Two Sides of the Same Coin?

open access: yesFrontiers in Physiology, 2021
The two lipocalins, β-lactoglobulin (βLg) and glycodelin (Gd), are possibly the most closely related members of the large and widely distributed lipocalin family, yet their functions appear to be substantially different.
Lindsay Sawyer
doaj   +1 more source

Endonuclease activity in lipocalins [PDF]

open access: yesBiochemical Journal, 2000
Several lipocalins contain conserved amino acid sequences similar to the phosphodiester bond cleavage domain of sugar non-specific magnesium-dependent nucleases of the Serratia marcescens type. His-89 and Glu-127 of the S. marcescens endonuclease are believed to have a role in the active catalytic site by the attack of a water molecule at the ...
T N, Yusifov   +3 more
openaire   +2 more sources

The diversity of lipocalin receptors

open access: yesBiochimie, 2022
Lipocalins are important carriers of preferentially hydrophobic molecules, but they can also bind other ligands, like highly polar siderophores or intact proteins. Consequently, they are involved in a variety of physiological processes in many species.
Bernhard Redl, Matthias Habeler
openaire   +2 more sources

Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages

open access: yesFrontiers in Immunology, 2022
Metabolic disorders (i.e., hyperglycemia, hyperlipidemia, and hyperinsulinemia) cause increased secretion of inflammatory cytokines/chemokines, leading to gradual loss of cardiac resident macrophage population and increased accumulation of inflammatory ...
Qianqian Li   +12 more
doaj   +1 more source

Lipocalin-2 and neutrophil activation in pancreatic cancer cachexia [PDF]

open access: yes, 2023
BackgroundCancer cachexia is a multifactorial syndrome characterized by body weight loss and systemic inflammation. The characterization of the inflammatory response in patients with cachexia is still limited.
Ulf P. Neumann   +9 more
core   +2 more sources

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