Results 21 to 30 of about 36,315 (164)

Dimerization of lipocalin allergens [PDF]

Scientific Reports, 2015
AbstractLipocalins are one of the most important groups of inhalant animal allergens. The analysis of structural features of these proteins is important to get insights into their allergenicity. We have determined two different dimeric crystal structures for bovine dander lipocalin Bos d 2, which was earlier described as a monomeric allergen.
Miettinen Ilja, Jänis Janne, Rouvinen Juha, Rytkönen-Nissinen Marja Anneli, Niemi Merja, Virtanen Tuomas   +5 more
openaire   +3 more sources

Features of coronary pathology and its relationship with myocardial fibrosis markers in patients with resistant hypertension

Российский кардиологический журнал, 2023
Aim. To evaluate the severity of coronary atherosclerosis and its association with biochemical markers of fibrosis in patients with coronary artery disease (CAD) and resistant hypertension (RHT).Material and methods.
V. A. Lichikaki, V. F. Mordovin, A. Yu. Falkovskaya, I. V. Zyubanova, M. A. Manukyan, E. I. Solonskaya, A. A. Vtorushina, S. A. Khunkhinova, I. A. Skomkina   +8 more
doaj   +1 more source

Endonuclease activity in lipocalins [PDF]

Biochemical Journal, 2000
Several lipocalins contain conserved amino acid sequences similar to the phosphodiester bond cleavage domain of sugar non-specific magnesium-dependent nucleases of the Serratia marcescens type. His-89 and Glu-127 of the S. marcescens endonuclease are believed to have a role in the active catalytic site by the attack of a water molecule at the ...
T N, Yusifov, A R, Abduragimov, O K, Gasymov, B J, Glasgow   +3 more
openaire   +2 more sources

Schwann cell-derived Apolipoprotein D controls the dynamics of post-injury myelin recognition and degradation

Frontiers in Cellular Neuroscience, 2014
Management of lipids, particularly signaling lipids that control neuroinflammation, is crucial for the regeneration capability of a damaged nervous system.
Nadia eGarcía-Mateo, Maria Dolores Ganfornina, Olimpio eMontero, Miguel A Gijón, Robert eMurphy, Diego eSanchez   +5 more
doaj   +1 more source

Mammalian derived lipocalin and secretoglobin respiratory allergens strongly bind ligands with potentially immune modulating properties

Frontiers in Allergy, 2022
Allergens from furry animals frequently cause sensitization and respiratory allergic diseases. Most relevant mammalian respiratory allergens belong either to the protein family of lipocalins or secretoglobins.
Bente Janssen-Weets, Bente Janssen-Weets, Frédéric Kerff, Kyra Swiontek, Stéphanie Kler, Rebecca Czolk, Rebecca Czolk, Dominique Revets, Annette Kuehn, Carsten Bindslev-Jensen, Markus Ollert, Markus Ollert, Christiane Hilger   +12 more
doaj   +1 more source

Lipocalins – a family portrait

Journal of Plant Physiology, 2006
Lipocalins are a widely distributed group of proteins whose common feature is the presence of six-or eight-stranded beta-barrel in their tertiary structure and highly conservative motifs short conserved region, (SCR) in their amino acid sequences. The presence of three SCRs is typical for kernel lipocalins, while outlier lipocalins have only one or two
Grzyb, Joanna, Latowski, Dariusz, Strzałka, Kazimierz   +2 more
openaire   +3 more sources

Lipocalin-2 and Cerebral Stroke

Frontiers in Molecular Neuroscience, 2022
Stroke is a common and devastating disease with an escalating prevalence worldwide. The known secondary injuries after stroke include cell death, neuroinflammation, blood-brain barrier disruption, oxidative stress, iron dysregulation, and neurovascular unit dysfunction.
Chao Luo, Shuai Zhou, Shuai Zhou, Shi Yin, Lipeng Jian, Pengren Luo, Jigeng Dong, Erheng Liu   +7 more
openaire   +3 more sources

Biological Functions of RBP4 and Its Relevance for Human Diseases

Frontiers in Physiology, 2021
Retinol binding protein 4 (RBP4) is a member of the lipocalin family and the major transport protein of the hydrophobic molecule retinol, also known as vitamin A, in the circulation.
Julia S. Steinhoff, Achim Lass, Achim Lass, Michael Schupp   +3 more
doaj   +1 more source

Levels of apolipoprotein M are not associated with the risk of coronary heart disease in two independent case-control studies

Journal of Lipid Research, 2008
Apolipoprotein M (apoM), a 25 kDa plasma protein belonging to the lipocalin protein family, is predominantly associated with HDL. Studies in mice have suggested apoM to be important for the formation of pre-β-HDL and to increase cholesterol efflux from ...
Josefin Ahnström, Olof Axler, Matti Jauhiainen, Veikko Salomaa, Aki S. Havulinna, Christian Ehnholm, Ruth Frikke-Schmidt, Anne Tybjærg-Hansen, Björn Dahlbäck   +8 more
doaj   +1 more source

Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7

Frontiers in Allergy, 2023
IntroductionPet lipocalins are respiratory allergens with a central hydrophobic ligand-binding cavity called a calyx. Molecules carried in the calyx by allergens are suggested to influence allergenicity, but little is known about the native ligands ...
Jungki Min, Alexander C. Y. Foo, Scott A. Gabel, Lalith Perera, Eugene F. DeRose, Anna Pomés, Lars C. Pedersen, Geoffrey A. Mueller   +7 more
doaj   +1 more source