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Evaluation of neutrophil gelatinase-associated lipocalin in normoalbuminuric normotensive type 1 diabetic adolescents

Journal of Pediatric Endocrinology and Metabolism, 2012
The aims of this study were to determine neutrophil gelatinase-associated lipocalin (NGAL) levels in normoalbuminuric and normotensive adolescents with type 1 diabetes and to assess the relationship between NGAL and clinical and laboratory variables.Forty-six adolescents with type 1 diabetes [male/ female (M/F) ratio, 24/22; median age, 14.5 years ...
DEMİR, KORCAN   +5 more
openaire   +3 more sources

Kidney injury molecule-1 and neutrophil gelatinase associated lipocalin in normoalbuminuric diabetic children

Journal of Pediatric Endocrinology and Metabolism, 2016
AbstractWe aimed at evaluating the urinary levels of kidney injury molecule-1 ( KIM-1) and neutrophil gelatinase associated lipocalin (NGAL), and the relationship between these markers and clinical and laboratory variables in normoalbuminuric children with type 1 diabetes (T1D).The study group consisted of 60 (F/M: 28/32) children with T1D with a ...
Ucakturk, Ahmet   +4 more
openaire   +3 more sources

Neutrophil gelatinase-associated lipocalin and Endothelin-1 as markers for the onset and severity of preeclampsia

Annals of Medical Laboratory Science, 2022
Background: The onset of preeclampsia (PE) may be early (EOPE), or late (LOPE). Preeclampsia may also be characterized by severe features (PS) or without severe features (PNS). This study aimed to predict the onset and severity of PE using biomarkers including neutrophil gelatinase-associated lipocalin (sNGAL) and endothelin-1 (ET-1). Method: This was
openaire   +1 more source

Fluorescent aptasensor based on G-quadruplex-assisted structural transformation for the detection of biomarker lipocalin 1

Biosensors and Bioelectronics, 2020
Diabetic retinopathy (DR) is the leading global cause of blindness in the working-age population. Early diagnosis and intervention can effectively reduce the risk for blindness. However, the current diagnostic methods in clinical practice remain constrained by nonquantitative examinations and individual ophthalmologists' experiences.
Shunxiang, Gao   +4 more
openaire   +2 more sources

Human Lipocalin-1 Association with3H-Testosterone and3H-Estradiol

Current Eye Research, 2009
Topical androgens and estrogens have been studied for use in treating ocular conditions such as dry eye. The aim of this study was to identify proteins from normal human tears that associated with exogenously added sex steroid hormones. One of the major proteins in ocular tears is lipocalin-1.
Jean M, Crow   +2 more
openaire   +2 more sources

Progelatinase B Forms from Human Neutrophils. Complex Formation of Monomer/Lipocalin with TIMP-1

Biological Chemistry Hoppe-Seyler, 1996
The three forms of neutrophil gelatinase B-monomer, homodimer and monomer/lipocalin complex-, were isolated from phorbolester stimulated neutrophil granulocytes by chromatography on gelatin-Sepharose and heparin-Ultrogel. On average, about 50% of the monomer/lipocalin complex was found to be complexed with TIMP-1. After activation with trypsin monomer,
H, Kolkenbrock   +4 more
openaire   +2 more sources

Neutrophil gelatinase-associated lipocalin, but not kidney injury marker-1, correlates with duration of delayed graft function

Transplant Immunology, 2014
<b><i>Background:</i></b> No specific early biomarker is available to measure kidney injury after kidney transplantation (KT). Both neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury marker 1 (KIM-1) increase after oxidative injury.
Eline Kristina van den Akker   +5 more
openaire   +2 more sources

Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Marker of Diabetic Nephropathy in Type 1 Diabetic Patients

Clinical Laboratory, 2018
Glomerular and tubulointerstitial damage plays a role in renal function failure in diabetic patients. While both serum and urine levels of neutrophil gelatinase-associated lipocalin (NGAL) show significantly increased levels in acute renal pathologies, the NGAL increase in active phase indicates a reversible condition in chronic cases.52 type 1 ...
Dirican, MELEHAT   +5 more
openaire   +4 more sources

Detection of low-abundance biomarker lipocalin 1 for diabetic retinopathy using optoelectrokinetic bead-based immunosensing

Biosensors and Bioelectronics, 2017
Early diagnosis of diabetic retinopathy (DR) is vital but challenging. DR is a common complication and a major cause of vision loss in patients with diabetes mellitus. Without appropriate medical intervention, visual impairment may become a great burden to our healthcare system. In clinical practice, the current diagnostic methods, such as fluorescence
Jhih-Cheng, Wang   +3 more
openaire   +2 more sources

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