Results 211 to 220 of about 29,733,047 (249)

Effects of Sacubitril/Valsartan versus Irbesartan on Urine Tubular Biomarkers in Chronic Kidney Disease: Findings from the UK HARP-III Trial.

open access: yesAm J Nephrol
Goonasekera MA   +17 more
europepmc   +1 more source

α1-Microglobulin: a yellow-brown lipocalin

open access: yesBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2000
alpha(1)-Microglobulin, also called protein HC, is a lipocalin with immunosuppressive properties. The protein has been found in a number of vertebrate species including frogs and fish. This review summarizes the present knowledge of its structure, biosynthesis, tissue distribution and immunoregulatory properties.
B, Akerström   +4 more
openaire   +3 more sources

Determination of the T cell epitopes of the lipocalin allergen, Rat n 1

open access: yesClinical & Experimental Allergy, 2004
SummaryBackground Laboratory animal allergy (LAA) is an important cause of occupational sensitization and asthma. Rats are a frequent cause of LAA and the major rat allergen, Rat n 1, is a member of the lipocalin protein family, which includes several other animal allergens such as the cow allergen, Bos d 2. To date, Bos d 2 is the only mammalian
Jeal, H   +5 more
openaire   +4 more sources

Evaluation of neutrophil gelatinase-associated lipocalin in normoalbuminuric normotensive type 1 diabetic adolescents

open access: yesJournal of Pediatric Endocrinology and Metabolism, 2012
The aims of this study were to determine neutrophil gelatinase-associated lipocalin (NGAL) levels in normoalbuminuric and normotensive adolescents with type 1 diabetes and to assess the relationship between NGAL and clinical and laboratory variables.Forty-six adolescents with type 1 diabetes [male/ female (M/F) ratio, 24/22; median age, 14.5 years ...
DEMİR, KORCAN   +5 more
openaire   +4 more sources
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Lipocalin-1: a potential marker for noninvasive aneuploidy screening

Fertility and Sterility, 2011
This study has identified the first protein, lipocalin-1, in the secretome of human blastocysts that is associated with chromosome aneuploidy. The development of a noninvasive technique to determine an embryo's developmental competence, including chromosomal constitution, by analysis of spent IVF culture medium will be a powerful tool for embryo ...
Susanna, McReynolds   +5 more
openaire   +2 more sources

The lipocalin α1-microglobulin binds heme in different species

Archives of Biochemistry and Biophysics, 2004
The lipocalin alpha(1)-microglobulin (alpha(1)m), found in plasma and tissues of various vertebrates, is brown, forms complexes with other proteins and has immunomodulatory effects in vitro, but the physiological function is not yet established. Human alpha(1)m was recently shown to bind heme and, after cleavage of a C-terminal tetrapeptide, initiate ...
Jörgen, Larsson   +2 more
openaire   +2 more sources

An intriguing member of the lipocalin protein family: α1-microglobulin

Trends in Biochemical Sciences, 1990
The plasma protein alpha 1-microglobulin is a member of the lipocalin protein superfamily. In the last few years, the work on alpha 1-microglobulin has given unexpected and promising new results. Of particular interest are its molecular association with immunoglobulin A and with proteinase inhibitors, and its interactions with the immune system.
B, Akerström, L, Lögdberg
openaire   +2 more sources

Expression, characterization and ligand specificity of lipocalin-1 interacting membrane receptor (LIMR)

Molecular Membrane Biology, 2013
Human lipocalin-1 interacting membrane receptor (LIMR) was the first lipocalin receptor to be identified, as a specific receptor for lipocalin-1 (Lcn1). Subsequently LIMR has been reported to interact with other ligands as well, notably with the bovine lipocalin β-lactoglobulin (BLG) and with the unrelated secretoglobin uteroglobin (UG).
Renske W, Hesselink, John B C, Findlay
openaire   +2 more sources

Human Lipocalin-1 Association with3H-Testosterone and3H-Estradiol

Current Eye Research, 2009
Topical androgens and estrogens have been studied for use in treating ocular conditions such as dry eye. The aim of this study was to identify proteins from normal human tears that associated with exogenously added sex steroid hormones. One of the major proteins in ocular tears is lipocalin-1.
Jean M, Crow   +2 more
openaire   +2 more sources

Kidney injury molecule-1 and neutrophil gelatinase associated lipocalin in normoalbuminuric diabetic children

Journal of Pediatric Endocrinology and Metabolism, 2016
AbstractWe aimed at evaluating the urinary levels of kidney injury molecule-1 ( KIM-1) and neutrophil gelatinase associated lipocalin (NGAL), and the relationship between these markers and clinical and laboratory variables in normoalbuminuric children with type 1 diabetes (T1D).The study group consisted of 60 (F/M: 28/32) children with T1D with a ...
Ucakturk, Ahmet   +4 more
openaire   +3 more sources

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