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Tirzepatide for Lipodystrophy

Abstract Background Lipodystrophy encompasses a group of rare disorders associated with severe metabolic disease. These disorders are defined by abnormal fat distribution, with near-total (generalized lipodystrophy, GL) or partial (partial lipodystrophy, PL; i.e. familial partial lipodystrophy, FPLD)
Rasimcan Meral   +11 more
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Lipodystrophy: A case report of partial lipodystrophy of the face

British Journal of Oral Surgery, 1977
Lipodystrophy is a disorder of the subcutaneous adipose tissue. It can occur in two forms--partial and total. Gorlin and Goldman (1970) suggested that facial lipodystrophy can only occur bilaterally, and should it occur unilaterally, then it is hemifacial atrophy. A case is reported to illustrate that partial lipodystrophy can occur unilaterally.
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LIPODYSTROPHY

Journal of the American Medical Association, 1932
Atrophy of the subcutaneous tissues producing depressed areas on the skin as a result of insulin injections was first reported in 1926 by Barborka. 1 He noted two instances of such atrophy and recommended massage of the tissue after insulin therapy and a variation of the site of injection.
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LIPODYSTROPHY

American Journal of Diseases of Children, 1940
Lipodystrophia progressiva is a condition in which, characteristically, there is a loss of the subcutaneous fat of the face, neck, thorax, arms and abdomen without assignable cause or gross symptoms of ill health.1The loss of fat is symmetric and slowly progressive to the stage of almost complete disappearance in the affected areas.2An essential ...
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Lipodystrophy

The Indian Journal of Pediatrics, 1965
S D, Singh   +2 more
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Mesenteric Lipodystrophy

Annals of Internal Medicine, 1974
R E, Kipfer, C G, Moertel, D C, Dahlin
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[Lipodystrophies].

La Revue de medecine interne, 2014
Human lipodystrophies represent a group of diseases characterized by altered body fat amount and/or repartition. Most forms of lipodystrophies are associated with metabolic alterations such as insulin resistance, diabetes and dyslipemia, leading to diabetic complications, increased cardiovascular risk or liver steatosis.
L, Fardet, C, Vigouroux, J, Capeau
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Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy

Diabetes, 2023
Caleigh Mandel-Brehm   +2 more
exaly  

Lipodystrophies

Plastic and Reconstructive Surgery, 1966
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[Lipodystrophies].

Klinische Padiatrie, 2002
The lipodystrophy syndromes are rare disorders characterized by the loss of adipose tissue. The loss of fat tissue can have genetic, immune, or infectious/drug-associated causes. With the extent of fat loss metabolic complications, such as insulin resistance, diabetes mellitus, hypertriglyceridemia, and fatty liver increase in severity. Lipodystrophies
Pamela, Fischer-Posovszky   +2 more
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