Inhibition of the key metabolic pathways, glycolysis and lipogenesis, of oral cancer by bitter melon extract [PDF]
, 2019 Subhayan Sur +6 more
openalex +1 more source
Genome-Wide Association Study Identifies Novel Loci Associated With Concentrations of Four Plasma Phospholipid Fatty Acids in the De Novo Lipogenesis Pathway [PDF]
, 2013 Jason Wu +27 more
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International Journal of Cancer, EarlyView.What's New? Higher pre‐diagnostic body mass index has been associated with higher risk of mortality in individuals with colorectal cancer; however, the mechanism remains unclear. This prospective analysis of incident colorectal cancer cases within the European Prospective Investigation into Cancer and Nutrition cohort study addressed potential collider
Thu Thi Pham +25 more
wiley +1 more source
COFACTOR REQUIREMENTS FOR LIPOGENESIS
Journal of Biological Chemistry, 1953 Samuel Gurin, Jessie Van Baalen
openaire +3 more sources
International Journal of Cancer, EarlyView.Abstract Hepatocellular carcinoma (HCC) represents the predominant form of primary liver cancer and is frequently identified at a late stage, necessitating systemic therapy. However, resistance to first‐line tyrosine kinase inhibitor therapies, such as sorafenib and lenvatinib, remains a significant clinical challenge.
Longtao Zhao +6 more
wiley +1 more source
Genetic variants underlying precancerous conditions of hepatocellular carcinoma
International Journal of Cancer, EarlyView.Abstract Hepatocellular carcinoma (HCC) is the most common form of liver cancer, accounting for 80% of cases worldwide. While chronic hepatitis B and C infections remain primary risk factors, emerging evidence highlights the increasing contributions of metabolic dysfunction‐associated steatotic liver disease (MASLD) and alcohol‐associated liver disease
Jonathan Jaime G. Guerrero +7 more
wiley +1 more source
Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer
International Journal of Cancer, EarlyView.Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley +1 more source
Both Hepatic Lipogenesis and Beta-Oxidation are Altered in Offspring of Mothers Fed a High-Fat Diet in the First Two Generations (F1 and F2) [PDF]
, 2015 Wilian Rodrigues Lannes +5 more
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Early matrine intervention of gut microbiota for type 2 diabetes prevention
iMetaOmics, EarlyView.How matrine influences gut microbiota imbalance to prevent the progression of diabetes remains unclear. We conduct experiments using mice to simulate the stages of diabetes development and matrine intervention. Combined with amplicon sequencing, we find that the gut microbiota of diabetic mice continuously changes with the progression of the disease ...
Zhexue Sun +4 more
wiley +1 more source
RF32 | PSUN44 CARF Regulates Non-Alcoholic Fatty Liver Diseases (NAFLD) by Controlling ER Stress and Lipogenesis in Hepatic Cells. [PDF]
, 2022 Theodore C. Friedman +8 more
openalex +1 more source