Results 151 to 160 of about 77,919 (340)

Reprogramming SREBP1‐dependent lipogenesis and inflammation in high‐risk breast with licochalcone A: A novel path to cancer prevention

International Journal of Cancer, EarlyView.
What's New? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan, Elizabeth T. Bartom, Carolina H. Chung, Xingyu Guo, Kyli Berkley, Seyyedmohsen Hosseinibarkooie, Zahra Assadi, Shao Huan Samuel Weng, Raymond Moellering, Oukseub Lee, Ruohui Chen, Wonhwa Cho, Sriram Chandrasekaran, Susan E. Clare, Seema A. Khan   +14 more
wiley   +1 more source

Functional relationship of thyroid hormone-induced lipogenesis, lipolysis, and thermogenesis in the rat. [PDF]

, 1991
Jack H. Oppenheimer, Harold L. Schwartz, James T. Lane, Mick Thompson   +3 more
openalex   +1 more source

Early matrine intervention of gut microbiota for type 2 diabetes prevention

iMetaOmics, EarlyView.
How matrine influences gut microbiota imbalance to prevent the progression of diabetes remains unclear. We conduct experiments using mice to simulate the stages of diabetes development and matrine intervention. Combined with amplicon sequencing, we find that the gut microbiota of diabetic mice continuously changes with the progression of the disease ...
Zhexue Sun, Hujie Lyu, Hailang Xu, Xianjin Qin, Wei Li   +4 more
wiley   +1 more source

The expression of genes involved in jejunal lipogenesis and lipoprotein synthesis is altered in morbidly obese subjects with insulin resistance [PDF]

, 2015
Carolina Gutiérrez‐Repiso, Francisca Rodríguez‐Pacheco, Juan Antonio García-Arnés, Sergio Valdés, Montserrat Gonzalo, Federico Soriguer, Francisco J. Moreno‐Ruiz, Alberto Rodríguez‐Cañete, Jose L. Gallego‐Perales, Guillermo Alcaín‐Martínez, Luis Vázquez‐Pedreño, Soledad López, Sara García‐Serrano, Lourdes Garrido‐Sánchez, Eduardo Garcı́a-Fuentes   +14 more
openalex   +1 more source

COFACTOR REQUIREMENTS FOR LIPOGENESIS

Journal of Biological Chemistry, 1953
J, VAN BAALEN, S, GURIN
openaire   +2 more sources

Host‐driven hepatic conversion of gut microbiota‐derived putrescine to spermidine mediates mannose's protective effects against hepatic steatosis in zebrafish

iMeta, EarlyView.
Evidence for liver metabolism of gut‐derived microbial compounds into beneficial secondary metabolites has been lacking. Here, we demonstrate that Cetobacterium somerae (C. somerae), enriched by mannose supplementation under high‐fat diet conditions, convert arginine into putrescine.
Delong Meng, Zhen Zhang, Tsegay Teame, Benjamin Earl Niemann, Rui Xia, Shichang Xu, Yajie Zhao, Yalin Yang, Chao Ran, Le Luo Guan, Zhigang Zhou   +10 more
wiley   +1 more source

Neonatal overfeeding induced glucocorticoid overexposure accelerates hepatic lipogenesis in male rats [PDF]

, 2018
Fan Yang, Yanyan Dai, Cuiting Min, Xiaonan Li   +3 more
openalex   +1 more source

Nano‐plastics disrupt systemic metabolism by remodeling the bile acid–microbiota axis and driving hepatic–intestinal dysfunction

iMeta, EarlyView.
The pervasiveness of microplastic pollution poses a growing health risk, yet its long‐term metabolic consequences remain poorly defined. Here, we exposed mice to polyethylene terephthalate nanoparticle (NP) and combined histopathology, biochemistry, metabolomics, and metagenomics to resolve their interactions.
Yi Zhang, Zheng Lin, Runtong Huang, Yang Zhang, Lei Wang, Zan Fu, Chao Wang, Shuai Xiao, Heru Pramono, Kui Xu, Zhimin Xu, Yulong Yin   +11 more
wiley   +1 more source

Cutaneous Lipogenesis IV. Role of the Pentose Phosphate Pathway During Lipogenesis in Guinea Pig Ear Skin

, 1973
Victor R. Wheatley, Mutukumara Kumarisiri, Joel Brind   +2 more
openalex   +1 more source

The role of the gut microbiome in the regulation of high‐altitude adaptation

iMeta, EarlyView.
This study is the first to elucidate mechanisms of high‐altitude adaptation from the perspective of the rumen ecosystem by using indigenous yaks and Holstein cows that have lived at high altitude since birth as comparative models. Through a systematic comparison of their rumen ecology using multi‐omics approaches—including rumen metagenomics ...
Xinyu Zhang, Senlin Zhu, Michael Kreuzer, Shoukun Ji, Wei Wang, Yanliang Bi, Shengli Li   +6 more
wiley   +1 more source