Results 191 to 200 of about 24,646 (237)

Synthetic lipopeptides as novel adjuvants

Research in Immunology, 1992
Lipopeptides constitute potent novel immunoadjuvants in mice, rabbits and other species, enhancing markedly the immune response when given in mixture with antigens. Lipopeptides are non-toxic, non-pyrogenic and do not induce tissue damage when injected.
W G, Bessler, G, Jung
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Lipopeptide adjuvants in combination treatment

International Immunopharmacology, 2003
Synthetic lipopeptides derived from the N-terminus of bacterial lipoprotein constitute potent immunoadjuvants for parenteral and mucosal immunization. When combined with tetanus toxoid (TT) or gliadin as antigens, the lipopeptide N-palmitoyl-S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]-(R)-cysteinyl-seryl-(lysyl)(3)-lysine (P(3)CSK(4)) markedly enhanced the ...
Bessler, Wolfgang G., Mittenbühler, Klaus, Esche, Ulrich vor dem, Huber, Maria   +3 more
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Enrichment and Purification of Lipopeptide Biosurfactants

2010
A great many methods are available for the concentration of biosurfactants from microbiological media. The strongest known biosurfactant, surfactin, serves as a model in many studies, so is used here to illustrate the diversity in approaches to product enrichment.
Simon C, Baker, Chien-Yen, Chen
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Structure elucidation of bacterial nonribosomal lipopeptides

Organic & Biomolecular Chemistry, 2020
We provide a summary of the tools, which allow elucidate the structures of nonribosomal lipopetides.
Sebastian Götze, Pierre Stallforth
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Solid-Phase Synthesis of Octapeptin Lipopeptides

2019
Octapeptins are naturally derived cyclic lipopeptide antibiotics with activity against a range of Gram-negative pathogens, including highly resistant strains. Octapeptin C4, an exemplar of the class, was synthesized using a combination of Fmoc solid-phase peptide synthesis (SPPS) and solution-phase cyclization.
Hansford, Karl A., Ziora, Zyta M., Cooper, Matthew A., Blaskovich, Mark A. T.   +3 more
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Removal of heavy metals from aqueous solution by lipopeptides and lipopeptides modified Na-montmorillonite

Bioresource Technology, 2013
The removal of Cu(2+), Zn(2+), Cd(2+), Pb(2+) and Hg(2+) from aqueous solution by lipopeptides produced from solid-state fermentation (LPSSF) and LPSSF modified Na-montmorillonite clays (LPSSF/Na-MMT) was investigated. The results showed that the LPSSF had certain adsorption capability for the metal ions and the modification of Na-MMT with LPSSF at a ...
Zhen, Zhu, Chao, Gao, Yanliang, Wu, Lifei, Sun, Xiaolei, Huang, Wei, Ran, Qirong, Shen   +6 more
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Therapeutic Update on Glycopeptide and Lipopeptide Antibiotics

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1988
Glycopeptide antibiotics in the form of vancomycin have been available for almost 30 years. In the past, vancomycin usually was reserved as an alternative agent to treat staphylococcal and streptococcal infection in patients with a penicillin allergy or hemodialysis shunt infection. With the increasing frequency of both methicillin‐
J C, Rotschafer, M W, Garrison, K A, Rodvold   +2 more
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Synthetische Lipopeptide

2009
Lipoproteine mit der N-terminalen Struktur des Trispalmitoyl-Cysteins (Pam3Cys) finden sich in den Membranen einer Vielzahl von Bakterien. Strukturanaloge synthetische Lipopeptide sind zudem Gegenstand intensiver Forschungen bezüglich einer therapeutischen Anwendung als Adjuvantien.
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Novel dendrimeric lipopeptides with antifungal activity

Bioorganic & Medicinal Chemistry Letters, 2012
A series of new cationic lipopeptides containing branched, amphiphilic polar head derived from (Lys)Lys(Lys) dendron and C(8) or C(12) chain at C-end were designed, synthesized and characterized. Antimicrobial in vitro activity expressed as minimal inhibitory concentration (MIC) was evaluated against Gram-positive and Gram-negative bacteria and yeasts ...
Jolanta, Janiszewska, Marta, Sowińska, Aleksandra, Rajnisz, Jolanta, Solecka, Izabela, Łącka, Sławomir, Milewski, Zofia, Urbańczyk-Lipkowska   +6 more
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The Cyclic Lipopeptide Antibiotics

2017
The cyclic lipopeptides comprise a number of clinically relevant classes of antibiotics that date back from the discovery of the polymyxins in 1947 to the recent introduction of the semi-synthetic lipoglycopeptides. These natural products and natural product derivatives most often originate from soil-inhabiting and/or plant-derived producing organisms.
Laurens H. J. Kleijn, Nathaniel I. Martin   +1 more
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