Results 111 to 120 of about 16,928 (191)

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales, Ana Clara Lunardi Yagi, Túlio Custódio Reis, Jessica Ingrid Cazorla, Jade Rojas Villar, Marcia A. Graminha, Roxana Yesenia Pastrana Alta, Fernando Rogério Pavan   +7 more
wiley   +1 more source

Construction of LP-LNP with novel lipopeptides as adjuvants and its enhancing effects on mRNA vaccines

陆军军医大学学报
Objective To construct lipid nanoparticles (lipopeptide-lipid nanoparticle, LP-LNP) with novel lipopeptides as adjuvants, and initially explore their synergistic effect on mRNA vaccines.
CAO Jingwen, CAO Jingwen, CHI Yu, LI Guocheng   +3 more
doaj   +1 more source

Untersuchung von Anti‐Glykan‐Antikörpern und Erforschung ihres medizinischen Potenzials mithilfe synthetischer Glykane

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
Anti‐Glykan‐Antikörper spielen sowohl bei Gesundheit als auch bei Krankheit eine wesentliche Rolle. Der Zugang zu neuartigen Glykanstrukturen ermöglicht Fortschritte bei der Antikörpercharakterisierung für die Entdeckung von Biomarkern, die Antikörperentwicklung und das Impfstoffdesign.
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Short cationic lipopeptides as effective antibacterial agents: design, physicochemical properties and biological evaluation

, 2016
The spread of drug-resistant bacteria has imparted a sense of urgency in the search for new antibiotics. In an effort to develop a new generation of antibacterial agents, we have designed de novo charged lipopeptides inspired by natural antimicrobial ...
Marasini, Nirmal, Blaskovich, Mark A. T., Kavanagh, Angela M., Elliott, Alysha G., Skwarczynski, Mariusz, Azmi, Fazren, Ziora, Zyta, Cooper, Matthew A., Toth, Istvan, Ramu, Soumya   +9 more
core   +1 more source

Synthetic lipopeptides that interact with lipopolysaccharides are potent bactericidal compounds against Xylella fastidiosa

Applied and Environmental Microbiology
Novel strategies to control diseases caused by Xylella fastidiosa that affect important crops like grapevine, olive, almond, and citrus are necessary to prevent its establishment and spread in several countries. Target-oriented functional peptides toward
Pau Caravaca-Fuentes, Laura Montesinos, Jordi Lamata, Marta Planas, Lidia Feliu, Emilio Montesinos   +5 more
doaj   +1 more source

Harnessing Marine Bacterial Lipopeptides for Sustainable Disease Management in Open Sea Cage Aquaculture

Oceans
The open ocean cage aquaculture system is facing considerable challenges with disease outbreaks resulting from over-farming and the rise of resistance to antimicrobial treatment.
Sumit Kumar, Ajit Kumar, Akshatha Soratur, Ankit Sarkar, Balu Alagar Venmathi Maran   +4 more
doaj   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Different charged short lipopeptides

, 2011
Series of short peptides palmitoylated in different positions was designed, synthesized and tested for antimicrobial activities. The palmitoyl group was situated either on the alpha - amino group in position 1 or on the epsilon - amino group of lysine ...
Ježek, R.
core  

Bacterial Lipopeptides Are Effective against Pear Fire Blight

Microorganisms
Fire blight, a devastating disease caused by Erwinia amylovora, poses a significant threat to pear and apple trees in Xinjiang province, China. In an effort to combat this pathogen, we isolated 10 bacteria from various components of apple and crabapple ...
Ihsan ud Din, Lina Hu, Yuan Jiang, Jie Wei, Muhammad Afzal, Li Sun   +5 more
doaj   +1 more source

Bacillus velezensis Y6, a Potential and Efficient Biocontrol Agent in Control of Rice Sheath Blight Caused by Rhizoctonia solani

Microorganisms
Rice sheath blight is a serious disease caused by Rhizoctonia solani that reduces rice yield. Currently, there is a lack of efficient and environmentally friendly control methods. In this study, we found that Bacillus velezensis (B.
Huan Tao, Xiaoyu Li, Huazhen Huo, Yanfei Cai, Aihua Cai   +4 more
doaj   +1 more source