Results 31 to 40 of about 15,558 (228)

Genotoxicity of cationic lipopeptide nanoparticles

Toxicology Letters, 2020
The genotoxicity of cationic lipopeptide nanoparticles (cLPNPs) was evaluated in vivo and in vitro comet assay and the in vivo chromosome aberrations test. In vitro comet assay, human blood cells were exposed to cLPNPs at the concentration of 2.5, 5, 10, 20, 40 and 100 μg/mL.
Aliy K. Zhanataev, Elena A. Anisina, Alla V. Kulakova, Igor P. Shilovskiy, Artem A. Lisitsyn, Olesya O. Koloskova, Musa R. Khaitov, Andrey D. Durnev   +7 more
openaire   +3 more sources

Characterization of Lipopeptide Biosurfactants Produced by Bacillus licheniformis MB01 from Marine Sediments

Frontiers in Microbiology, 2017
Antibiotic resistance has become one of the world’s most severe problems because of the overuse of antibiotics. Antibiotic-resistant bacteria are more difficult to kill and more expensive to treat. Researchers have been studied on antibiotic alternatives
Yulin Chen, Yulin Chen, Shiliang A. Liu, Haijin Mou, Yunxiao Ma, Meng Li, Xiaoke Hu   +6 more
doaj   +1 more source

Highly Immunogenic Nanoparticles Based on a Fusion Protein Comprising the M2e of Influenza A Virus and a Lipopeptide

Viruses, 2020
The highly conserved extracellular domain of the transmembrane protein M2 (M2e) of the influenza A virus is a promising target for the development of broad-spectrum vaccines. However, M2e is a poor immunogen by itself and must be linked to an appropriate
Anna A. Zykova, Elena A. Blokhina, Roman Y. Kotlyarov, Liudmila A. Stepanova, Liudmila M. Tsybalova, Victor V. Kuprianov, Nikolai V. Ravin   +6 more
doaj   +1 more source

ANTIMICROBIAL ACTIVITY OF LIPOPEPTIDES [PDF]

Postępy Mikrobiologii - Advancements of Microbiology, 2018
Abstract The constantly growing number of multidrug-resistant bacterial strains prompts the search for alternative treatments. Synthetic peptides based on natural antimicrobial peptides, also known as antimicrobial lipopeptides, can become a promising group of “drugs” to fight multi-resistant bacteria.
Paulina Czechowicz, Joanna Nowicka
openaire   +2 more sources

Bacillus lipopeptides inhibit lipase activity and promote 3T3-L1 preadipocyte differentiation

Journal of Enzyme Inhibition and Medicinal Chemistry
Bacillus lipopeptides have been reported to display anti-obesity effects. In the present study, Lipopeptides from Bacillus velezensis FJAT-45028 that consisted of iturin, fengycin and surfactin were reported.
Meichun Chen, Deju Chen, Rongfeng Xiao, Xuefang Zheng, Bo Liu, Jieping Wang   +5 more
doaj   +1 more source

MICROBIAL SURFACTANTS. II. LIPOPEPTIDES [PDF]

Biotechnologia Acta, 2014
The classification and the chemical structure of the lipopeptides and their producers (bacteria of the genera Bacillus and Pseudomonas) are given.
T. P. Pirog, A. D. Konon, A. P. Sofilkanich   +2 more
doaj   +1 more source

Regulation of cyclic lipopeptide biosynthesis in Pseudomonas fluorescens by the ClpP protease

, 2009
Cyclic lipopeptides produced by Pseudomonas species exhibit potent surfactant and broad-spectrum antibiotic properties. Their biosynthesis is governed by large multimodular nonribosomal peptide synthetases, but little is known about the genetic ...
Bruijn, I., de, Raaijmakers, J.M., de Bruijn, I.   +2 more
core   +1 more source

Lipopeptides as tools in catalysis, supramolecular, materials and medicinal chemistry

, 2023
Lipopeptides are amphiphilic peptides in which an aliphatic chain is attached to either the C or N terminus of peptides. Their self-assembly — into micelles, vesicles, nanotubes, fibres or nanobelts — leads to applications in nanotechnology, catalysis or
Vicente-García, C., Cesar Vicente-Garcia, Colomer, Ignacio, Ignacio Colomer   +3 more
core   +1 more source

The peptide sequence of diacyl lipopeptides determines dendritic cell TLR2-mediated NK activation. [PDF]

PLoS ONE, 2010
Natural killer (NK) cells are lymphocyte effectors that are activated to control certain microbial infections and tumors. Many NK-activating and regulating receptors are involved in regulating NK cell function.
Masahiro Azuma, Ryoko Sawahata, Yuusuke Akao, Takashi Ebihara, Sayuri Yamazaki, Misako Matsumoto, Masahito Hashimoto, Koichi Fukase, Yukari Fujimoto, Tsukasa Seya   +9 more
doaj   +1 more source

Solubilization and stabilization of isolated photosystem I complex with lipopeptide detergents. [PDF]

PLoS ONE, 2013
It is difficult to maintain a target membrane protein in a soluble and functional form in aqueous solution without biological membranes. Use of surfactants can improve solubility, but it remains challenging to identify adequate surfactants that can ...
Xiaoqiang Wang, Guihong Huang, Daoyong Yu, Baosheng Ge, Jiqian Wang, Fengxi Xu, Fang Huang, Hai Xu, Jian R Lu   +8 more
doaj   +1 more source