Results 11 to 20 of about 640,235 (385)
The Role of Lipopolysaccharide-Induced Cell Signalling in Chronic Inflammation
Chronic Stress, 2022 Lipopolysaccharide (LPS) is the main structural component of the outer membrane of most Gram-negative bacteria and has diverse immunostimulatory and procoagulant effects.
M. Page, D. Kell, E. Pretorius
semanticscholar +1 more source
Periodontitis and cardiometabolic disorders: The role of lipopolysaccharide and endotoxemia
Periodontology, 2022 Lipopolysaccharide is a virulence factor of gram‐negative bacteria with a crucial importance to the bacterial surface integrity. From the host's perspective, lipopolysaccharide plays a role in both local and systemic inflammation, activates both innate ...
P. Pussinen +6 more
semanticscholar +1 more source
Interaction between Lipopolysaccharide and Gut Microbiota in Inflammatory Bowel Diseases
International Journal of Molecular Sciences, 2021 Lipopolysaccharides (LPSs) are bacterial surface glycolipids, produced by Gram-negative bacteria. LPS is known to determine acute inflammatory reactions, particularly in the context of sepsis. However, LPS can also trigger chronic inflammation.
M. Candelli +7 more
semanticscholar +1 more source
Ferrostatin-1 alleviates lipopolysaccharide-induced cardiac dysfunction
Bioengineered, 2021 Cardiac dysfunction is a common complication of sepsis, and is attributed to severe inflammatory responses. Ferroptosis is reported to be involved in sepsis-induced cardiac inflammation.
Zheng Xiao +6 more
semanticscholar +1 more source
Metabolic endotoxemia is dictated by the type of lipopolysaccharide
bioRxiv, 2021 Lipopolysaccharides (LPS) can promote metabolic endotoxemia, which is considered inflammatory and metabolically detrimental based on Toll-like receptor (TLR)4 agonists such as Escherichia coli-derived LPS.
F. F. Anhê +4 more
semanticscholar +1 more source
Recent Advances in Lipopolysaccharide Recognition Systems
International Journal of Molecular Sciences, 2020 Lipopolysaccharide (LPS), commonly known as endotoxin, is ubiquitous and the most-studied pathogen-associated molecular pattern. A component of Gram-negative bacteria, extracellular LPS is sensed by our immune system via the toll-like receptor (TLR)-4 ...
Lalita Mazgaeen, Prajwal Gurung
semanticscholar +1 more source
Journal of Integrative Neuroscience, 2022 Background: Lipopolysaccharide (LPS) administration is one of the most commonly used methods for inducing inflammation in animal models. Several animal studies have investigated the effects of acute and chronic peripheral administration of LPS on ...
Noor Ahmed Alzahrani +4 more
doaj +1 more source
Hydrogen Repairs LPS-Induced Endothelial Progenitor Cells Injury via PI3K/AKT/eNOS Pathway
Frontiers in Pharmacology, 2022 Endotoxins and other harmful substances may cause an increase in permeability in endothelial cells (ECs) monolayers, as well as ECs shrinkage and death to induce lung damage.
Qingjie Mu +16 more
doaj +1 more source
MYC Participates In Lipopolysaccharide-Induced Sepsis Via Promoting Cell Proliferation And Inhibiting Apoptosis [PDF]
Cell Journal, 2020 Objective This study aimed to explore the potential mechanism of MYC proto-oncogene, BHLH Transcription Factor (MYC) gene, on sepsis. Materials And Methods In this experimental study, rat-derived H9C2 cardiomyocyte cells were cultured in vitro ...
Yin Li +5 more
doaj +1 more source
Frontiers in Physiology, 2022 Neuroimmune interactions between the immune system and CNS as well as peripheral organs such as the liver play a key role in the pathophysiological state of diseases.
Yosuke Yamawaki +6 more
doaj +1 more source