Results 21 to 30 of about 471,242 (306)

Placental-mediated increased cytokine response to lipopolysaccharides: a potential mechanism for enhanced inflammation susceptibility of the preterm fetus. [PDF]

, 2012
BackgroundCerebral palsy is a nonprogressive motor impairment syndrome that has no effective cure. The etiology of most cases of cerebral palsy remains unknown; however, recent epidemiologic data have demonstrated an association between fetal neurologic ...
Belkacemi, Louiza, Beloosesky, Ron, Boles, Julie L, Desai, Mina, Ross, Michael G   +4 more
core   +1 more source

Correlation of Lipopolysaccharide Endotoxin Level in Cotton Dust with the Increase of TNFα Level and the Decline of Lung Function in Cotton Spinning Factory Workers [PDF]

, 2014
Lipopolysaccharide (LPS) endotoxin contained in cotton dust may cause airway inflammation and decline of lung function when inhaled, which eventually leads to respiratory symptoms.
Indahwati, L. (Leli), Keman, S. (Soedjajadi), Noviarmi, F. S. (Fadilatus)   +2 more
core   +2 more sources

Phosphodiesterase 4B is essential for lipopolysaccharide-induced CC chemokine ligand 3 production in mouse macrophages

Journal of Medical Sciences, 2015
Background: Phosphodiesterase 4 (PDE4) inhibitors negatively modulate many inflammatory responses, and some of these pharmacological effects are mediated by inhibition of PDE4B in inflammatory cells.
Ciou-Rong Lai, Huan-Chu Lo, Yi-Ling Chen, Jing-Xing Yang, Shiau-Li Ding, Hsian-He Hsu, Marco Conti, Chin-Pyng Wu, S L Catherine Jin   +8 more
doaj   +1 more source

Trapped lipopolysaccharide and LptD intermediates reveal lipopolysaccharide translocation steps across the Escherichia coli outer membrane [PDF]

, 2015
Lipopolysaccharide (LPS) is a main component of the outer membrane of Gram-negative bacteria, which is essential for the vitality of most Gram-negative bacteria and plays a critical role for drug resistance.
AX Tran, B van den Berg, C Dong, C Whitfield, CC Liu, DJ Sherman, E Freinkman, E Freinkman, EM Hearn, G Malojcic, G Zhang, H Dong, H Hong, H Liu, H Mori, JC Kauer, JC Whitney, JW Chin, KM Schultz, M Grabowicz, MA Khan, MD Suits, N Ruiz, NN Nickerson, P Sperandeo, P Sperandeo, QJ Xiang, R Villa, RE Bishop, RE Bishop, S Okuda, S Okuda, S Qiao, TS Young, Y Gu, Z Wang   +35 more
core   +1 more source

How periodontal disease may contribute to cardiovascular disease [PDF]

, 2000
No abstract ...
Kinane, D.F., Lowe, G.D.O.
core   +1 more source

Lipopolysaccharide antagonists

Immunology Today, 1992
Bacterial lipopolysaccharide (LPS) is a potent and pleiotropic stimulus of immune cells. LPS has important clinical relevance because it has a direct role in the pathogenesis of Gram-negative bacterial infection. The lipid A moiety of LPS is responsible for the toxic effects of LPS.
W A, Lynn, D T, Golenbock
openaire   +2 more sources

Nanocurcumine Ameliorates Lipopolysaccharide-induced Depressive-like Behavior in Mice [PDF]

Nanomedicine Research Journal, 2018
Objective(s): Curcumin, a plant alkaloid from Curcuma longa, possess antioxidant and anti-inflammatory properties. Recently, the antidepressant activities of curcumin were reported. Nevertheless, bioavailability of curcumin limits its therapeutic utility.
Nahid Fakhraei, Seyyedeh Elaheh Mousavi, Seyed Pouyan Pishva, Seyed Mahdi Rezayat, Fatemeh Mohammadi   +4 more
doaj   +1 more source

Microbial translocation and T cell activation are modified by direct-acting antiviral therapy in HCV-infected patients [PDF]

, 2018
BACKGROUND: Microbial translocation from the gut lumen has been involved in the pathogenesis of liver damage in hepatitis C virus (HCV) infection. AIM: To investigate the impact of direct-acting antiviral treatment on microbial translocation and T ...
Baroncelli, Silvia, DE SANTIS, Adriano, GINANNI CORRADINI, Stefano, Lattanzi, Barbara, Lupo1, Marinella, Maria Galluzzo, Clementina, Mennini, Gianluca, Merli, Manuela, Michelini, Zuleika, Palmisano, Lucia, Rossi, Massimo   +10 more
core   +1 more source

Phosphate Groups in the Lipid A Moiety Determine the Effects of LPS on Hepatic Stellate Cells: A Role for LPS-Dephosphorylating Activity in Liver Fibrosis

Cells, 2020
Alkaline phosphatase (AP) activity is highly upregulated in plasma during liver diseases. Previously, we demonstrated that AP is able to detoxify lipopolysaccharide (LPS) by dephosphorylating its lipid A moiety. Because a role of gut-derived LPS in liver
Marlies Schippers, Eduard Post, Ilse Eichhorn, Jitske Langeland, Leonie Beljaars, Madhu S. Malo, Richard A. Hodin, José Luis Millán, Yury Popov, Detlef Schuppan, Klaas Poelstra   +10 more
doaj   +1 more source

Transcriptional activation and regulation of urokinase plasminogen activator inducted by LPS through MyD88 independent pathway in rat Sertoli cells

Folia Histochemica et Cytobiologica, 2021
INTRODUCTION: Urokinase plasminogen activator (uPA) is a serine protease and it also demonstrates proinflammatory properties. We thus hypothesized that uPA is involved in immunity of Sertoli cells in the rat testis.
Yan Liu, Kai Zhao, Zhe Xiong, Yuanxiao Yi, Chengliang Xiong, Donghui Huang, Hu Zhao   +6 more
doaj   +1 more source