Results 11 to 20 of about 264,633 (217)

Transcriptional activation and regulation of urokinase plasminogen activator inducted by LPS through MyD88 independent pathway in rat Sertoli cells

Folia Histochemica et Cytobiologica, 2021
INTRODUCTION: Urokinase plasminogen activator (uPA) is a serine protease and it also demonstrates proinflammatory properties. We thus hypothesized that uPA is involved in immunity of Sertoli cells in the rat testis.
Yan Liu, Kai Zhao, Zhe Xiong, Yuanxiao Yi, Chengliang Xiong, Donghui Huang, Hu Zhao   +6 more
doaj   +1 more source

SPECIFICITY OF IMMUNE MODULATING EFFECT OF YERSINIA PESTIS ENDOTOXIN

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Literature and own data on mechanisms of realization of lipopolysaccharide (LPS) toxic potential of Yersinia pestis in the conditions of a macroorganism are analyzed.
V. I. Tynyanova, V. P. Zyuzina, G. V. Demidova, E. P. Sokolova   +3 more
doaj   +1 more source

Antioxidative, Antiapoptotic, and Anti-Inflammatory Effects of Apamin in a Murine Model of Lipopolysaccharide-Induced Acute Kidney Injury

Molecules, 2020
Sepsis is the major cause of acute kidney injury (AKI) in severely ill patients, but only limited therapeutic options are available. During sepsis, lipopolysaccharide (LPS), an endotoxin derived from bacteria, activates signaling cascades involved in ...
Jung-Yeon Kim, Jaechan Leem, Kwan-Kyu Park   +2 more
doaj   +1 more source

Loss of YhcB results in overactive fatty acid biosynthesis

mBio
Loss of the Escherichia coli inner membrane protein YhcB results in pleomorphic cell morphology and clear growth defects. Prior work suggested that YhcB was directly involved in cell division or peptidoglycan assembly.
Hannah M. Stanley, M. Stephen Trent
doaj   +1 more source

Research Note: Poria cocos polysaccharide alleviates lipopolysaccharide-induced intestinal inflammation and barrier damage in broiler chickens

Poultry Science
: This study aimed to explore the impact of dietary supplementation of Poria cocos polysaccharide (PCP) on the lipopolysaccharide(LPS)-induced intestinal inflammation, morphology, and barrier damage in broilers.
Jinzhou Zhang, Yuting Zhang, Yuya Wang, Wenbo Hou, Dongyang Liu, Zhiguo Miao   +5 more
doaj   +1 more source

Ishige okamurae Attenuates Neuroinflammation and Cognitive Deficits in Mice Intracerebroventricularly Injected with LPS via Regulating TLR-4/MyD88-Dependent Pathways

Antioxidants, 2022
Neuroinflammation is one of the critical causes of neuronal loss and cognitive impairment. We aimed to evaluate the anti-neuroinflammatory properties of Ishige okamuae using mice intracerebroventricularly injected with lipopolysaccharides (LPS) and LPS ...
Oh-Yun Kwon, Seung-Ho Lee
doaj   +1 more source

Alpha-Mangostin Suppresses LPS-Induced Inflammation in Human Dental Pulp Cells

Applied Sciences, 2023
Xanthones are secondary metabolites isolated from the peel of mangosteen showing medicinal potencies. Alpha-mangostin (α-MG) is the most plentiful xanthone, which has been reported to possess anti-inflammatory, anti-oxidant, and anti-bacterial activities.
Yu-Seon Kim, Ji-Hyun Jang, Jeong-Tae Koh, Yun-Chan Hwang, Won-Mann Oh, Bin-Na Lee   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Protective effects of Dioscin against sepsis‐induced cardiomyopathy via regulation of toll‐like receptor 4/MyD88/p65 signal pathway

Immunity, Inflammation and Disease
Background Dioscin has many pharmacological effects; however, its role in sepsis‐induced cardiomyopathy (SIC) is unknown. Accordingly, we concentrate on elucidating the mechanism of Dioscin in SIC rat model.
Meng Zhang, Deyuan Zhi, Pei Liu, Yajun Wang, Meili Duan   +4 more
doaj   +1 more source

Chlorogenic Acid Intravesical Therapy Changes Acute Voiding Behavior of Systemic Lipopolysaccharide Inflammation-Induced Cystitis Bladder in Mice

Toxics
This study explores the potential efficacy of chlorogenic acid (CGA) in mitigating lipopolysaccharide (LPS)-induced cystitis in a mice model. C57BL/6J mice were divided into four groups: normal control (NC), LPS, LPS + low CGA, and LPS + high CGA ...
Chung-Hsin Yeh, Chellappan Praveen Rajneesh, Chun-Hou Liao, Wen-Chen You, Kuo-Chiang Chen, Yi-No Wu, Han-Sun Chiang   +6 more
doaj   +1 more source