Trapped lipopolysaccharide and LptD intermediates reveal lipopolysaccharide translocation steps across the Escherichia coli outer membrane [PDF]
, 2015 C.D. is a recipient of the Wellcome Trust Investigator award (WT106121MA). W.W. is supported by Science and Technology Program of Guangzhou, China (201510010040).Lipopolysaccharide (LPS) is a main component of the outer membrane of Gram-negative bacteria,
Dong, H. +9 more
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Novel biphasic role of lipoxinA4 on expression of cyclooxygenase-2 in lipopolysaccharide-stimulated lung fibroblasts [PDF]
, 2011 Fibroblasts are important to host defence and immunity, can also as initiators of inflammation as well. As the endogenous "braking signal", Lipoxins can regulate anti-inflammation and the resolution of inflammation.
Gao, F. +24 more
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Structural and functional studies of bacterial outer membrane lipopolysaccharide insertion and Schmallenberg virus replication [PDF]
, 2015 Lipopolysaccharide (LPS) is an essential component of the outer membrane (OM) of Gram-negative bacteria and plays a fundamental role in protecting the bacteria from harsh environments and toxic compounds.
Dong, Haohao
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Heat shock inhibits lipopolysaccharide-induced tissue factor activity in human whole blood [PDF]
, 2007 Background During gram-negative sepsis, lipopolysaccharide (LPS) induces tissue factor expression on monocytes. The resulting disseminated intravascular coagulation leads to tissue ischemia and worsens the prognosis of septic patients.
Thielmann, Matthias +11 more
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Local lung responses following endobronchial elastase and lipopolysaccharide instillation in sheep [PDF]
, 2006 Chronic lipopolysaccharide (LPS) exposure may contribute to the pathogenesis of a number of lung diseases including COPD and emphysema. We sought to develop a large-animal model of emphysema using repeated LPS administration into sheep lung segments.
Blundell, Richard +8 more
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Lipopolysaccharide-induced activation of NF-κB non-canonical pathway requires BCL10 serine 138 and NIK phosphorylations. [PDF]
, 2010 Background and Aims: B-cell lymphoma / leukemia (BCL)-10 and reactive oxygen species mediate two pathways of NF-κB (RelA) activation by lipopolysaccharide (LPS) in human colonic epithelial cells.
Sumit Bhattacharyya (14205) +3 more
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Leptin fails to blunt the lipopolysaccharide-induced activation of the hypothalamic-pituitary-adrenal axis in rats [PDF]
, 2014 Copyright @ 2013 The authors. This work is licensed under a Creative Commons Attribution 3.0 Unported License.Obesity is a risk factor for sepsis morbidity and mortality, whereas the hypothalamic-pituitary-adrenal (HPA) axis plays a protective role in ...
Bloom, SR +5 more
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Cancer Medicine, 2018 The chronic infection of hepatitis B virus (HBV) is the most potent risk factor for the development of cirrhosis and hepatocellular carcinoma (HCC). The association of intestinal microbiota alteration with progressive liver disease has been investigated ...
Ashraf Mohamadkhani
doaj +1 more source
Effect of mevalonate, zoledronate and BCG on monocyte/macrophage phenotype
Сибирский научный медицинский журнал, 2023 Cells of innate immunity, mainly monocytes/macrophages, form a long-term nonspecific immunological memory during the initial encounter with the pathogen, the so-called trained immunity.
A. P. Lykov +5 more
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Development of a bead-based Luminex assay using lipopolysaccharide specific monoclonal antibodies to detect biological threats from Brucella species [PDF]
, 2015 Brucella, a Gram-negative bacterium, is classified as a potential bioterrorism agent mainly due to the low dose needed to cause infection and the ability to transmit the bacteria via aerosols.
Angelika Silbereisen +9 more
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