Results 251 to 260 of about 640,235 (385)

Megasphaera Elesdenii Dysregulates Colon Epithelial Homeostasis, Aggravates Colitis‐Associated Tumorigenesis

open access: yesAdvanced Science, EarlyView.
A fecal microbial meta‐analysis reveals that Megasphaera is highly abundant in the Asian population with IBD and CRC. M. elsdenii reshapes colonic immunity by triggering DC cell‐mediated Th1 and Th17 inflammation. M. elsdenii and M. elsdenii‐enriched microbiota exacerbate colonic inflammation and tumorigenesis in AOM/DSS mice.
Xinxin Hou   +9 more
wiley   +1 more source

MicroRNA‐Enriched Plant‐Derived Exosomes Alleviate Colitis by Modulating Systemic Immunity, Metabolic Homeostasis, and Gut Microbiota

open access: yesAdvanced Science, EarlyView.
Herbal medicine, with its multicomponent and multitarget potential, is often studied primarily for traditional forms, especially phytochemicals. Currently, ulcerative colitis lacks natural, low‐toxicity therapies, yet emerging research highlights plant‐derived exosomes as a promising option.
Ruipeng Shi   +9 more
wiley   +1 more source

2-((3-(chloromethyl) benzoyl) oxy) benzoic acid suppresses NF-κB expression in the kidneys and lungs of LPS-Induced BALB/C mice. [PDF]

open access: yesJ Adv Pharm Technol Res
Foe K   +13 more
europepmc   +1 more source

Src Reduces Neutrophil Extracellular Traps Generation and Resolves Acute Organ Damage

open access: yesAdvanced Science, EarlyView.
Src reduces neutrophil extracellular traps (NETs) generation and resolves acute organ damage. Src directly activates RAF1 by regulating phosphorylation at the Ser 621 site and mediates the RAF/MEK/ERK pathway, thereby affecting the intracellular ROS production. Alternatively, Src activates the RAF1/MEK/ERK pathway by mediating PKC phosphorylation.
Guotao Lu   +18 more
wiley   +1 more source

Does lipopolysaccharide-mediated inflammation have a role in OA?

open access: yesNature Reviews Rheumatology, 2016
Zeyu Huang, V. Kraus
semanticscholar   +1 more source

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