Results 231 to 240 of about 351,832 (297)

The integrated stress response kinase GCN2 prevents ZAKα-Dependent inflammatory hyperactivation in macrophages. [PDF]

J Biol Chem
Requião RD, Lima-Silva LF, Estevão P, Costa WLG, Zani NC, Vasconcelos IC, Silva ÍEP, Xu TT, Prado HMDA, Steigenberger B, Bengtson MH, Murray PJ, Moraes-Vieira PM.   +12 more
europepmc   +1 more source

Design of a Novel Diamine Biosensor to Guide the Engineering of Escherichia coli for Cadaverine Overproduction

Advanced Science, EarlyView.
A high‐throughput screening platform was established by integrating an in vivo cadaverine biosensor with a fluorescence‐activated cell sorting (FACS) system. Biosensor‐driven specific exporter tuning, pathway optimization and genome‐wide target mining were conducted to maximize cadaverine production in Escherichia coli.
Jia Feng, Getao Liu, Ding Ma, Jiaxiang Yuan, Xinyi Zhang, Weihao Wang, Chen Ma, Yang Liao, Siyuan Gao, Lei Qin, Jiao Feng, Sheng Xu, Xin Wang, Kequan Chen   +13 more
wiley   +1 more source

Evaluation of the Potential Anti-Inflammatory Effect of a New Coumarin-Quinoline Hybrid in LPS-Induced Neuroinflammation. [PDF]

Pharmaceuticals (Basel)
Shehata OHM, Abdelaziz E, Ali H, Elmongy EI, Binsuwaidan R, Ibrahim WM, El-Gamasy S, Tantawy El Sayed IE.   +7 more
europepmc   +1 more source

Matrix Rigidity Mechanoprimes Microglia for Inflammation Through Cytoskeletal‐to‐Nuclear Signaling and 3D Spatio‐Epigenomic Remodeling

Advanced Science, EarlyView.
Pathological tissue rigidity mechanoprimes microglia by enhancing actin cytoskeleton–nucleus coupling and chromatin opening at rigidity‐responsive cis‐regulatory elements (mechanoCREs). Subsequent NF‐κB/p65 signaling converges on this permissive regulatory state to amplify inflammatory gene expression and microglial activation.
Yu Xuan Meng, Jaegeon Joo, Yu Meng Li, Cheng Ji Li, Ali Taghizadeh, Seung Jae Shin, Buuvee Bayarkhangai, Tae‐Woo Ha, Sak Lee, Jaewoo Chung, Bo‐Eun Yoon, Hye Sung Kim, Inkyung Jung, Jung‐Hwan Lee, Kam W. Leong, Hae‐Won Kim   +15 more
wiley   +1 more source

Effect of longevity genotype on acute phase response to a lipopolysaccharide challenge in dairy goats. [PDF]

PLoS One
Ithurbide M, Rupp R, Fassier T, Friggens NC, Foucras G.   +4 more
europepmc   +1 more source

Beyond Probiotics: Postbiotics for Healthy Aquaculture

Advanced Science, EarlyView.
This critical review assesses limitations of probiotics and proposes postbiotics, preparations of inanimate microorganisms and their metabolites, as a more stable, controlled, and biosafe formulation. Postbiotics offer significant advantages during industrial aquafeed production and storage. However, their practical implementation is currently hindered
Michael Leonidas Chikindas, Delin Xu, Igor V. Popov, Kayque Ordonho Carneiro, Nilufar Arashovna Elova, Gullola Amirovna Bekmurodova, Dildora Amindjanovna Amirsaidova, Astghik Pepoyan, Shakhlo Mirjamalovna Miralimova, Oleg V. Mitrokhin, Liubov S. Sichel, John Tagg, Svetoslav Dimitrov Todorov   +12 more
wiley   +1 more source

Network-Based Analysis for the Quantification of Brain and Body Immune Axes with Total-Body PET Imaging. [PDF]

J Nucl Med
Maccioni L, Knyzeliene A, Alcaide-Corral CJ, Reid VJM, Morgan TEF, Henry MC, Sutherland A, Veronese M, Tavares AAS.   +8 more
europepmc   +1 more source

Association Between Preoperative Mechanical Bowel Preparation and Postoperative Cognitive Dysfunction in Patients Undergoing Colorectal Surgery: A Pilot Randomized Controlled Trial. [PDF]

Ther Clin Risk Manag
Ülgey A, Talih G, Talih T, Sener EF, Ozsoy S, Şimşek OK, Sönmez E, Dana H.   +7 more
europepmc   +1 more source