Results 21 to 30 of about 519,050 (337)

Peripheral Immune Activation in Mice Elicits Unfolded Protein Responses Independent on MyD88 Pathway in the Liver but not the Hypothalamus and Hippocampus

Frontiers in Physiology, 2022
Neuroimmune interactions between the immune system and CNS as well as peripheral organs such as the liver play a key role in the pathophysiological state of diseases.
Yosuke Yamawaki, Yosuke Yamawaki, Hitomi Kimura, Susumu Nagata, Koichiro Ozawa, Toru Hosoi, Toru Hosoi   +6 more
doaj   +1 more source

Persistent systemic microbial translocation, inflammation, and intestinal damage during Clostridioides difficile infection [PDF]

, 2020
Background. Clostridioides difficile infection (CDI) might be complicated by the development of nosocomial bloodstream infection (n-BSI). Based on the hypothesis that alteration of the normal gut integrity is present during CDI, we evaluated markers of ...
Aversano, L., Battaglia, R., Bruno, G., Ciardi, M. R., Corazziari, E. S., de Angelis, M., Iera, J., Mascellino, M. T., Mastroianni, C. M., Miele, M. C., Morelli, S., Oliva, A., Venditti, M., Vullo, V.   +13 more
core   +1 more source

SPECIFICITY OF IMMUNE MODULATING EFFECT OF YERSINIA PESTIS ENDOTOXIN

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Literature and own data on mechanisms of realization of lipopolysaccharide (LPS) toxic potential of Yersinia pestis in the conditions of a macroorganism are analyzed.
V. I. Tynyanova, V. P. Zyuzina, G. V. Demidova, E. P. Sokolova   +3 more
doaj   +1 more source

Antioxidative, Antiapoptotic, and Anti-Inflammatory Effects of Apamin in a Murine Model of Lipopolysaccharide-Induced Acute Kidney Injury

Molecules, 2020
Sepsis is the major cause of acute kidney injury (AKI) in severely ill patients, but only limited therapeutic options are available. During sepsis, lipopolysaccharide (LPS), an endotoxin derived from bacteria, activates signaling cascades involved in ...
Jung-Yeon Kim, Jaechan Leem, Kwan-Kyu Park   +2 more
doaj   +1 more source

Degalactosylated Whey Protein Suppresses Inflammatory Responses Induced by Lipopolysaccharide in Mice

Frontiers in Nutrition, 2022
The effects of degalactosylated whey protein on lipopolysaccharide (LPS)-induced inflammatory responses in mice were observed in comparison with intact whey protein.
Toshio Inui, Toshio Inui, Toshio Inui, Namiko Kawamura, Riho Nakama, Akio Inui, Goro Katsuura   +6 more
doaj   +1 more source

Integrated dataset on acute phase protein response in chicken challenged with Escherichia coli lipopolysaccharide endotoxin [PDF]

, 2018
Data herein describe the quantitative changes in the plasma proteome in chickens challenged with lipopolysaccharide (LPS), a bacterial endotoxin known to stimulate the host innate immune system obtained by shotgun quantitative proteomic tandem mass tags ...
Bain, Maureen, Eckersall, Peter David, Guillemin, Nicolas, Horvatić, Anita, Kaab, Haider, Kuleš, Josipa, McKeegan, Dorothy, O'Reilly, Emily   +7 more
core   +3 more sources

Prenatal infection predisposes offspring to enhanced susceptibility to imiquimod-mediated psoriasiform dermatitis in mice

Dermatologica Sinica, 2022
Background: Infection can upregulate T helper 17 (Th17) signaling and exacerbate psoriasis. Literature has indicated that prenatal infection induces embryonic development toward Th17 signaling and is a risk factor for developing certain Th17-skewing ...
Sebastian Yu, Chia-Wen Lee, Yu-An Li, Tsung-Hsi Chen, Hsin-Su Yu   +4 more
doaj   +1 more source

Improved induced innate immune response after cART initiation in people with HIV

Frontiers in Immunology, 2022
IntroductionImpairment of the innate immune function may contribute to the increased risk of bacterial and viral infections in people with HIV (PWH).
Malene Hove-Skovsgaard, Dina Leth Møller, Annemette Hald, Jan Gerstoft, Jan Gerstoft, Jens Lundgren, Jens Lundgren, Sisse Rye Ostrowski, Sisse Rye Ostrowski, Susanne Dam Nielsen, Susanne Dam Nielsen   +10 more
doaj   +1 more source

RomA, A Periplasmic Protein Involved in the Synthesis of the Lipopolysaccharide, Tunes Down the Inflammatory Response Triggered by Brucella [PDF]

, 2018
Brucellaceae are stealthy pathogens with the ability to survive and replicate in the host in the context of a strong immune response. This capacity relies on several virulence factors that are able to modulate the immune system and in their structural ...
Altabe, Silvia Graciela, Casabuono, Adriana Cristina, Cassataro, Juliana, Couto, Alicia Susana, Czibener, Cecilia, Fulgenzi, Fabiana Rosa, Guaimas, Francisco Fernando, Pasquevich, Karina Alejandra, Spera, Juan Manuel, Ugalde, Juan Esteban, Valguarnera, Pablo Ezequiel   +10 more
core   +1 more source

Antioxidant mitoquinone ameliorates EtOH-LPS induced lung injury by inhibiting mitophagy and NLRP3 inflammasome activation

Frontiers in Immunology, 2022
Chronic ethanol abuse is a systemic disorder and a risk factor for acute respiratory distress syndrome (ARDS) and chronic obstructive pulmonary disease (COPD). However, the mechanisms involved are unknown.
Wenhua Sang, Wenhua Sang, Sha Chen, Lidan Lin, Nan Wang, Xiaoxia Kong, Jinyan Ye   +6 more
doaj   +1 more source