Results 11 to 20 of about 82,562 (259)

Effects of Lipopolysaccharide from Porphyromonas gingivalis and Escherichia coli on Gene Expression Levels of Toll-like Receptors and Inflammatory Cytokines in Human Dental Pulp Stem Cells [PDF]

Iranian Journal of Immunology, 2022
Background: Periodontal diseases originate from a group of oral inflammatory infections initiated by oral pathogens. Among these pathogens, Gram-negative bacteria such as p. gingivalis play a major role in chronic periodontitis. P.
Hanieh Mojtahedi, Nikoo Hossein-khannazer, Seyed Mahmoud Hashemi, Mina Masoudnia, Monireh Askarzadeh, Arash Khojasteh, Mandana Sattari   +6 more
doaj   +1 more source

Liquid PRF Reduces the Inflammatory Response and Osteoclastogenesis in Murine Macrophages

Frontiers in Immunology, 2021
Macrophage activation and osteoclastogenesis are hallmarks of inflammatory osteolysis and may be targeted by the local application of liquid platelet-rich fibrin (PRF).
Zahra Kargarpour, Jila Nasirzade, Layla Panahipour, Richard J. Miron, Reinhard Gruber, Reinhard Gruber   +5 more
doaj   +1 more source

Esculetin Alleviates Acute Liver Failure following Lipopolysaccharide/D-Galactosamine in Male C57BL/6 Mice [PDF]

Iranian Journal of Medical Sciences, 2021
Background: Acute liver failure (ALF) is a fatal clinical situation that rapidly leads to the loss of normal liver function. Esculetin is a natural herbal compound used for the management of various diseases such as cardiovascular and renal disorders. In
Seyed-Mahdi Mohamadi-Zarch, Tourandokht Baluchnejadmojarad, Davood Nourabadi, Samira Ramazi, Morteza Nazari-Serenjeh, Mehrdad Roghani   +5 more
doaj   +1 more source

Protective role of curcumin against lipopolysaccharide-induced inflammation and apoptosis in human neutrophil [PDF]

Anesthesia and Pain Medicine, 2020
Background Sepsis, an uncontrolled host response to infection, may be life-threatening organ injury. Neutrophils play a critical role in regulation of host immune response to infection.
Kyu Bum Cho, Cheon Hee Park, Joungmin Kim, Tran Duc Tin, Sang-Hyun Kwak   +4 more
doaj   +1 more source

Sepsis-Associated Encephalopathy: The Blood–Brain Barrier and the Sphingolipid Rheostat

Frontiers in Immunology, 2017
Sepsis is not only a significant cause of mortality worldwide but has particularly devastating effects on the central nervous system of survivors. It is therefore crucial to understand the molecular structure, physiology, and events involved in the ...
Stephen J. Kuperberg, Raj Wadgaonkar
doaj   +1 more source

Madecassoside Protects Against LPS-Induced Acute Lung Injury via Inhibiting TLR4/NF-κB Activation and Blood-Air Barrier Permeability

Frontiers in Pharmacology, 2020
Madecassoside (MA), a crucial ingredient of Centella asiatica, has been reported to exhibit a variety of bioactivities, including antipulmonary fibrosis, and antiinflammatory effects.
Lu-Yuan Peng, Hai-Tao Shi, Meng Yuan, Jing-He Li, Ke Song, Jiang-Ni Huang, Peng-Fei Yi, Hai-Qing Shen, Ben-Dong Fu   +8 more
doaj   +1 more source

Heat Sepsis Precedes Heat Toxicity in the Pathophysiology of Heat Stroke—A New Paradigm on an Ancient Disease

Antioxidants, 2018
Heat stroke (HS) is an ancient illness dating back more than 2000 years and continues to be a health threat and to cause fatality during physical exertion, especially in military personnel, fire-fighters, athletes, and outdoor laborers.
Chin Leong Lim
doaj   +1 more source

Determination of the optimal concentration and duration of C5aR antagonist application in an inflammatory model of human dental pulp cells

FEBS Open Bio, 2023
Deep tooth decay approaching the pulp may develop into pulpitis; to prevent this, pulp cells need to balance the rapid immune response to avoid rapid swelling of the pulp.
Junlong Hu, Xiaohan Tan, Xiaoling Wei, Weiping Hu, Li Gao, Xiaofang Cao, Huiying Yang, Zhuling Jiang, Ning Li, Li Teng, Mingyue Liu   +10 more
doaj   +1 more source

Mesenteric Lymphatic Alterations Observed During DSS Induced Intestinal Inflammation Are Driven in a TLR4-PAMP/DAMP Discriminative Manner

Frontiers in Immunology, 2019
Background: Inflammatory bowel disease (IBD) is characterized by both acute and chronic phase inflammation of the gastro-intestinal (GI) tract that affect a large and growing number of people worldwide with little to no effective treatments.
Matthew Stephens, Shan Liao, Pierre-Yves von der Weid   +2 more
doaj   +1 more source

Lipopolysaccharide antagonists

Immunology Today, 1992
Bacterial lipopolysaccharide (LPS) is a potent and pleiotropic stimulus of immune cells. LPS has important clinical relevance because it has a direct role in the pathogenesis of Gram-negative bacterial infection. The lipid A moiety of LPS is responsible for the toxic effects of LPS.
W A, Lynn, D T, Golenbock
openaire   +2 more sources