Results 21 to 30 of about 125,833 (306)

Looking beyond endotoxin: a comparative study of pyrogen retention by ultrafilters used for the preparation of sterile dialyis fluid [PDF]

open access: yes, 2014
Sterile single-use ultrafilters are used in dialysis for the preparation of the substitution fluid given to patients undergoing dialysis treatments with high convective fluid removal.
Brodbeck, Katrin   +5 more
core   +2 more sources

Heat Sepsis Precedes Heat Toxicity in the Pathophysiology of Heat Stroke—A New Paradigm on an Ancient Disease

open access: yesAntioxidants, 2018
Heat stroke (HS) is an ancient illness dating back more than 2000 years and continues to be a health threat and to cause fatality during physical exertion, especially in military personnel, fire-fighters, athletes, and outdoor laborers.
Chin Leong Lim
doaj   +1 more source

Innate immunity, assessed by plasma NO measurements, is not suppressed during the incubation fast in eiders [PDF]

open access: yes, 2006
Immunity is hypothesized to share limited resources with other physiological functions and may mediate life history trade-offs, for example between reproduction and survival.
Adamo   +62 more
core   +3 more sources

Determination of the optimal concentration and duration of C5aR antagonist application in an inflammatory model of human dental pulp cells

open access: yesFEBS Open Bio, 2023
Deep tooth decay approaching the pulp may develop into pulpitis; to prevent this, pulp cells need to balance the rapid immune response to avoid rapid swelling of the pulp.
Junlong Hu   +10 more
doaj   +1 more source

Mesenteric Lymphatic Alterations Observed During DSS Induced Intestinal Inflammation Are Driven in a TLR4-PAMP/DAMP Discriminative Manner

open access: yesFrontiers in Immunology, 2019
Background: Inflammatory bowel disease (IBD) is characterized by both acute and chronic phase inflammation of the gastro-intestinal (GI) tract that affect a large and growing number of people worldwide with little to no effective treatments.
Matthew Stephens   +2 more
doaj   +1 more source

Metabolic Endotoxemia, Feeding Studies and the Use of the Limulus Amebocyte (LAL) Assay; Is It Fit for Purpose?

open access: yesDiagnostics, 2020
The Limulus amebocyte assay (LAL) is increasingly used to quantify metabolic endotoxemia (ME), particularly in feeding studies. However, the assay was not intended to assess plasma at levels typically seen in ME. We aimed to optimize and validate the LAL
Karma Pearce   +3 more
doaj   +1 more source

Fetal skin as a pro-inflammatory organ: Evidence from a primate model of chorioamnionitis. [PDF]

open access: yes, 2017
BackgroundIntrauterine infection is a primary cause of preterm birth and fetal injury. The pro-inflammatory role of the fetal skin in the setting of intrauterine infection remains poorly characterized. Whether or not inflammation of the fetal skin occurs
Boonkasidecha, Suppawat   +4 more
core   +3 more sources

Eupafolin ameliorates lipopolysaccharide-induced cardiomyocyte autophagy via PI3K/AKT/mTOR signaling pathway [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2019
Objective(s): Eupafolin, a major active component of Eupatorium perfoliatum L., has anti-inflammatory and anti-oxidant properties. Lipopolysaccharide (LPS) is responsible for myocardial depression.
Yan Gao, Yi Zhang, Yangyang Fan
doaj   +1 more source

Impact of Comorbidity of Bronchial Asthma and Type 2 Diabetes Mellitus on the Expression and Functional Activity of TLR2 and TLR4 Receptors

open access: yesLife, 2023
Epidemiological data indicate the active progression of various forms of diabetes mellitus in patients with bronchial asthma (BA), but little is known about the mechanisms of comorbidity formation.
Yaroslav V. Radzyukevich   +2 more
doaj   +1 more source

Irisin Regulates the Functions of Hepatic Stellate Cells [PDF]

open access: yesEndocrinology and Metabolism, 2020
Background Hepatic stellate cells (HSCs) are known to play a fundamental role in the progression of liver fibrosis. Once HSCs are activated, they are involved in proliferation, migration, and contractility which are characteristics of liver fibrogenesis.
Hanh Nguyen Dong   +4 more
doaj   +1 more source

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