Results 21 to 30 of about 82,704 (260)

Eupafolin ameliorates lipopolysaccharide-induced cardiomyocyte autophagy via PI3K/AKT/mTOR signaling pathway [PDF]

Iranian Journal of Basic Medical Sciences, 2019
Objective(s): Eupafolin, a major active component of Eupatorium perfoliatum L., has anti-inflammatory and anti-oxidant properties. Lipopolysaccharide (LPS) is responsible for myocardial depression.
Yan Gao, Yi Zhang, Yangyang Fan
doaj   +1 more source

Impact of Comorbidity of Bronchial Asthma and Type 2 Diabetes Mellitus on the Expression and Functional Activity of TLR2 and TLR4 Receptors

Life, 2023
Epidemiological data indicate the active progression of various forms of diabetes mellitus in patients with bronchial asthma (BA), but little is known about the mechanisms of comorbidity formation.
Yaroslav V. Radzyukevich, Ninel I. Kosyakova, Isabella R. Prokhorenko   +2 more
doaj   +1 more source

Irisin Regulates the Functions of Hepatic Stellate Cells [PDF]

Endocrinology and Metabolism, 2020
Background Hepatic stellate cells (HSCs) are known to play a fundamental role in the progression of liver fibrosis. Once HSCs are activated, they are involved in proliferation, migration, and contractility which are characteristics of liver fibrogenesis.
Hanh Nguyen Dong, So Young Park, Cong Thuc Le, Dae-Hee Choi, Eun-Hee Cho   +4 more
doaj   +1 more source

Lipopolysaccharide antagonists

Immunology Today, 1992
Bacterial lipopolysaccharide (LPS) is a potent and pleiotropic stimulus of immune cells. LPS has important clinical relevance because it has a direct role in the pathogenesis of Gram-negative bacterial infection. The lipid A moiety of LPS is responsible for the toxic effects of LPS.
W A, Lynn, D T, Golenbock
openaire   +2 more sources

Nutraceutical Effect of Resveratrol on the Mammary Gland: Focusing on the NF-κb /Nrf2 Signaling Pathways

Animals, 2023
The aim of this study is to evaluate the defensive role of resveratrol, which is antagonistic to the oxidative stress and inflammation that is prompted by LPS in mammary tissue of female mice. Thirty adult mice were distributed into three groups (n = 10)
Muhammad Umair Ul Hassan Malik, Nighat Hashmi, Marium Khan, Zain ul Aabdin, Rokayya Sami, Amani H. Aljahani, Rasha A. Al-Eisa, Mamdoh S. Moawadh, Naseh A. Algehainy   +8 more
doaj   +1 more source

In silico characterization and expression analysis of selected Arabidopsis receptor-like kinase genes responsive to different MAMP inducers

Biologia Plantarum, 2015
Candidate Arabidopsis thaliana S-domain receptor-like kinase (SD-RLK) (At1g11330, At1g61430, and At1g61610) and leucine-rich repeat receptor-like kinase (LRR-RLK) (At1g51850, At2g19190, and At5g45840) genes were characterized utilizing PlantPAN, AGRIS ...
S.-A. New, L. A. Piater, I. A. Dubery
doaj   +1 more source

Haptoglobin buffers lipopolysaccharides to delay activation of NFκB

Frontiers in Immunology
It has remained yet unclear which soluble factors regulate the anti-inflammatory macrophage phenotype observed in both homeostasis and tumourigenesis. We show here that haptoglobin, a major serum protein with elusive immunoregulatory properties, binds ...
Laura Zein, Laura Zein, Josina Grossmann, Josina Grossmann, Helena Swoboda, Helena Swoboda, Christina Borgel, Christina Borgel, Bernhard Wilke, Bernhard Wilke, Stephan Awe, Andrea Nist, Thorsten Stiewe, Oliver Stehling, Oliver Stehling, Sven-Andreas Freibert, Sven-Andreas Freibert, Till Adhikary, Till Adhikary, Ho-Ryun Chung   +19 more
doaj   +1 more source

Effect of Angiogenesis and Lymphangiogenesis in Diesel Exhaust Particles Inhalation in Mouse Model of LPS Induced Acute Otitis Media

Frontiers in Cellular and Infection Microbiology, 2022
Lymphangiogenesis and angiogenesis might have significant involvement in the pathogenesis of otitis media with effusion. This study investigated the effect of diesel exhaust particles (DEP) on inflammation and lymphangiogenesis in a mouse model of acute ...
Byeong-Gon Kim, Byeong-Gon Kim, Da Yeon Choi, Min-Gyoung Kim, An-Soo Jang, Myung-Whan Suh, Myung-Whan Suh, Jun Ho Lee, Jun Ho Lee, Seung Ha Oh, Seung Ha Oh, Moo Kyun Park, Moo Kyun Park   +12 more
doaj   +1 more source

Protective effects of Bacillus licheniformis on growth performance, gut barrier functions, immunity and serum metabolome in lipopolysaccharide-challenged weaned piglets

Frontiers in Immunology, 2023
Bacillus licheniformis (B. licheniformis) is a well-accepted probiotic that has many benefits on both humans and animals. This study explored the effects of B. licheniformis on growth performance, intestinal mucosal barrier functions, immunity as well as
Xiaorong Yu, Zhenglie Dai, Guangtian Cao, Zhenchuan Cui, Ruiqiang Zhang, Yinglei Xu, Yanping Wu, Caimei Yang   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source